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Ethyl 4,4-difluoro-3-oxobutanoate

Ethyl 4,4-difluoro-3-oxobutanoate structure

CAS No.: 352-24-9

Chemical Name:: Ethyl 4,4-difluoro-3-oxobutanoate

Synonyms: ETHYL 4,4-DIFLUOROACETOACETATE;ETHYL 4,4-DIFLUORO-3-OXOBUTYRATE;AKOS B016254;AKOS MSC-0700;ART-CHEM-BB B016254;Ethyl 4,4-difluoroc;Difluoro aceto acetat;4-difluoro-3-oxobutanoate;4,4-difluoro-3-oxobutanoate;Ethyl 4,4-difluorocetoacetate

CBNumber:: CB4359962

Molecular Formula:: C6H8F2O3

Molecular Weight:: 166.12

MDL Number:: MFCD00039277

MOL File:: 352-24-9.mol

Last updated:2023-11-10 16:48:32

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Ethyl 4,4-difluoro-3-oxobutanoate Properties

Melting point	-46°C(lit.)
Boiling point	162 °C
Density	1,61 g/cm³
refractive index	1.407
Flash point	68℃
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	clear liquid
pka	8.61±0.46(Predicted)
color	Colorless to Almost colorless
InChIKey	CBDPWKVOPADMJC-UHFFFAOYSA-N
CAS DataBase Reference	352-24-9(CAS DataBase Reference)
EPA Substance Registry System	Ethyl 4,4-difluoroacetoacetate (352-24-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS07

Signal word

Warning

Hazard statements

H315-H319-H226

Precautionary statements

P305+P351+P338-P210-P280a-P303+P361+P353-P501a

Hazard Codes

F,Xi

Risk Statements

10-36/37/38-36/38

Safety Statements

26-36/37/39

RIDADR

1993

WGK Germany

Hazard Note

Flammable

TSCA

Yes

HazardClass

IRRITANT, FLAMMABLE

HS Code

2918300090

NFPA 704

	2
2		0

Ethyl 4,4-difluoro-3-oxobutanoate price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	E1018	Ethyl 4,4-Difluoroacetoacetate >96.0%(GC)	352-24-9	5g	$30	2021-12-16	Buy
TCI Chemical	E1018	Ethyl 4,4-Difluoroacetoacetate >96.0%(GC)	352-24-9	25g	$90	2024-03-01	Buy
TRC	E678440	Ethyl 4,4-Difluoroacetoacetate	352-24-9	10g	$165	2021-12-16	Buy
TRC	E678440	Ethyl 4,4-Difluoroacetoacetate	352-24-9	100g	$745	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0026027	ETHYL 4,4-DIFLUOROACETOACETATE 95.00%	352-24-9	5G	$782.76	2021-12-16	Buy

Product number	Packaging	Price	Buy
E1018	5g	$30	Buy
E1018	25g	$90	Buy
E678440	10g	$165	Buy
E678440	100g	$745	Buy
HCH0026027	5G	$782.76	Buy

Ethyl 4,4-difluoro-3-oxobutanoate Chemical Properties,Uses,Production

Uses

Ethyl 4,4-Difluoroacetoacetate is an intermediate used for the synthesis of pharmaceuticals such as potassium channel activators and β-alanine derived GABA-T antagonists.

Uses

Ethyl 4,4-difluoro-3-oxobutanoate is an intermediate used for the synthesis of pharmaceuticals such as potassium channel activators and β-alanine derived GABA-T antagonists.

Ethyl 4,4-difluoro-3-oxobutanoate synthesis

Synthesis of Ethyl 4,4-difluoro-3-oxobutanoate from Ethyl difluoroacetate and Ethyl acetate

Ethyl 4,4-difluoro-3-oxobutanoate Preparation Products And Raw materials

Raw materials

Preparation Products

4,4-Difluoro-3-hydroxy-butyric acid ethyl ester Ethyl5-(aminomethyl)-2-(difluoromethyl)pyridine-4-carboxylate

Ethyl 4,4-difluoro-3-oxobutanoate Suppliers

Global( 356)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Zibo Shiji Zhonglian Medical Technology Co., Ltd.	15069388126 15069388126	sales@sjzlpharm.com	China	61	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1807	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +86-18949832763	info@tnjchem.com	China	2989	55
Zjartschem	+86-571-8723 8903 jocelynpan@zjarts.com	jocelynpan@zjarts.com	CHINA	993	58

Supplier	Advantage
Zibo Shiji Zhonglian Medical Technology Co., Ltd.	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Time Chemicals CO., Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
Hefei TNJ Chemical Industry Co.,Ltd.	55
Zjartschem	58

View Lastest Price from Ethyl 4,4-difluoro-3-oxobutanoate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-01-02	Ethyl 4,4-difluoro-3-oxobutanoate 352-24-9	US $85.00-850.00 / kg	10kg	0.99	20tons	Zibo Hangyu Biotechnology Development Co., Ltd
2023-09-06	Ethyl 4,4-difluoro-3-oxobutanoate 352-24-9	US $0.00-0.00 / KG	1KG	99%	500000kg	Hebei Guanlang Biotechnology Co., Ltd.
2023-06-16	Ethyl 4,4-difluoro-3-oxobutanoate 352-24-9	US $1.00 / KG	25KG	99.0%	1000KG/th	Zibo Shiji Zhonglian Medical Technology Co., Ltd.

Ethyl 4,4-difluoro-3-oxobutanoate
352-24-9
US $85.00-850.00 / kg
0.99
Zibo Hangyu Biotechnology Development Co., Ltd

Ethyl 4,4-difluoro-3-oxobutanoate
352-24-9
US $0.00-0.00 / KG
99%
Hebei Guanlang Biotechnology Co., Ltd.

Ethyl 4,4-difluoro-3-oxobutanoate
352-24-9
US $1.00 / KG
99.0%
Zibo Shiji Zhonglian Medical Technology Co., Ltd.

Ethyl 4,4-difluoro-3-oxobutanoate Spectrum

Ethyl 4,4-difluoro-3-oxobutanoate(352-24-9)FT-IR

352-24-9(Ethyl 4,4-difluoro-3-oxobutanoate)Related Search:

Ethyl 2-chloro-4,4,4-trifluoroacetoacetate Ethyl 2-(ethoxymethylene)-4,4,4-trifluoroacetoacetate ETHYL PENTAFLUOROPROPIONYLACETATE Ethyl 4,4-difluoro-3-oxobutanoate Ethyl 4,4,4-trifluoroacetoacetate

ETHYL HEPTAFLUOROBUTYRYLACETATE ETHYL 2-METHYL-4,4,4-TRIFLUOROACETOACETATE ISOPROPYL 4,4,4-TRIFLUOROACETOACETATE ETHYL 2,2-DIFLUOROACETOACETATE Ethyl acetoacetate

ETHYL 4,4,4-TRIFLUORO-2-(TRIPHENYLPHOSPHORANYLIDENE)ACETOACETATE 4,4,4-TRIFLUORO-ACETOACETIC ACID TERT-BUTYL ESTER 4,4,4-TRIFLUORO-2-HYDROXYLIMINO-3-OXOBUTYRIC ACID ETHYL ESTER ETHYL 4,4,4-TRIFLUORO-2-METHOXY-3-OXOBUTYRATE ETHYL 3-([2-ACETYL-5-(TERT-BUTYL)-3-THIENYL]AMINO)-2-(2,2,2-TRIFLUOROACETYL)ACRYLATE

METHYL 4-([2-(ETHOXYCARBONYL)-4,4,4-TRIFLUORO-3-OXOBUT-1-ENYL]AMINO)THIOPHENE-3-CARBOXYLATE METHYL 2-([2-(ETHOXYCARBONYL)-4,4,4-TRIFLUORO-3-OXOBUT-1-ENYL]AMINO)BENZOATE METHYL 2-([2-(ETHOXYCARBONYL)-4,4,4-TRIFLUORO-3-OXOBUT-1-ENYL]AMINO)THIOPHENE-3-CARBOXYLATE

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AKOS MSC-0700 AKOS B016254 ART-CHEM-BB B016254 Difluoro aceto acetat Ethyl 4,4-difluoro-3-oxobutyrate 90% Ethyl4,4-difluoro-3-oxobutyrate90% 4,4-Difluoroacetoacetic acid ethyl ester Ethyl 4,4-difluoro-3-oxobutanoate 4,4-Difluoro-3-oxo butyric acid ethyl ester Ethyl 4,4-difluoro-3-oxobutanoate 90% 3-Oxo-4,4-difluorobutanoic acid ethyl ester 3-Oxo-4,4-difluorobutyric acid ethyl ester 4-difluoro-3-oxobutanoate Butanoic acid,4,4-difluoro-3-oxo-, ethyl ester Ethyl 4,4-difluoro-3-oxobutyrate, Ethyl 4,4-difluoro-3-oxobutanoate Ethyl 4,4-difluorocetoacetate SynonyMs Ethyl 4,4-difluoro-3-oxobutanoate 4,4-difluoro-ethyl acetoacetate Ethyl 4,4-difluorocetoacetate 4,4-Difluoro-3-oxobutanoic acid ethyl ester Ethyl 4,4-difluoro-3-ketobutyrate Ethyl 4,4-difluoroc 4,4-difluoro-3-oxobutanoate Ethyl-4 4-difluoroacetoacetate- >98% -purity (Pack 100GM X 3 Nos) Ethyl4,4-Difluoroacetoacetate> TIANFU CHEM---Ethyl 4,4-difluoro-3-oxobutanoate ETHYL 4,4-DIFLUORO-3-OXOBUTYRATE ETHYL 4,4-DIFLUOROACETOACETATE Butanoic acid, 4,4-difluoro-3-oxo-, ethyl ester (9CI, ACI) 4,4-difluoro-3-oxo-Butanoic acid ethyl ester (9CI ACI) 352-24-9 top