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Cynaroside

Cynaroside structure

CAS No.: 5373-11-5

Chemical Name:: Cynaroside

Synonyms: LUTEOLIN-7-O-GLUCOSIDE;luteoloside;PETUNIDIN;LUTEOLIN-7-GLUCOSIDE;Galuteolin;cinaroside;glucoluteolin;Luteolin 7-O-β-D-glucopyranoside;4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(.beta.-D-glucopyranosyloxy)-5-hydroxy-;CYNAROSIDE

CBNumber:: CB4369516

Molecular Formula:: C21H20O11

Molecular Weight:: 448.38

MDL Number:: MFCD06799436

MOL File:: 5373-11-5.mol

Last updated:2023-11-15 22:22:56

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Cynaroside Properties

Melting point	256～258℃
storage temp.	Sealed in dry,2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
Boiling point	838.1±65.0 °C(Predicted)
Density	1.713±0.06 g/cm3(Predicted)
pka	6.10±0.40(Predicted)
color	Yellow to Very Dark Yellow
Stability	Hygroscopic
InChIKey	PEFNSGRTCBGNAN-QNDFHXLGSA-N
LogP	-0.090 (est)
CAS DataBase Reference	5373-11-5(CAS DataBase Reference)
FDA UNII	98J6XDS46I

SAFETY

Risk and Safety Statements

Hazard Codes	Xi
Safety Statements	24/25
WGK Germany	3
RTECS	DJ3009400
HS Code	29389090

Cynaroside price More Price(44)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	1370837	Luteolin 7-O-Glucoside United States Pharmacopeia (USP) Reference Standard	5373-11-5	30mg	$692	2024-03-01	Buy
Sigma-Aldrich	03600585	Luteolin 7-glucoside primary pharmaceutical reference standard	5373-11-5	10mg	$475	2024-03-01	Buy
Cayman Chemical	25141	Luteoloside ≥98%	5373-11-5	5mg	$93	2024-03-01	Buy
Cayman Chemical	25141	Luteoloside ≥98%	5373-11-5	10mg	$130	2024-03-01	Buy
Sigma-Aldrich	74284	Luteolin 7-O-β-D-glucoside ≥98.0% (HPLC)	5373-11-5	10mg	$536	2024-03-01	Buy

Product number	Packaging	Price	Buy
1370837	30mg	$692	Buy
03600585	10mg	$475	Buy
25141	5mg	$93	Buy
25141	10mg	$130	Buy
74284	10mg	$536	Buy

Cynaroside Chemical Properties,Uses,Production

Effects

Luteolin has a strong bactericidal effect on the respiratory tract, and it is the main active ingredient in the treatment of bronchitis in Qinglan, a unique medicinal material in Xinjiang. Lowers the role of cholesterol in atherosclerosis and enhances capillary relaxation.

Description

Luteolin-7-O-glucoside is a flavonoid that has been found in many Chinese herbs with diverse biological activities. It reduces lactate dehydrogenase (LDH) and caspase-3 activities and production of reactive oxygen species (ROS) and increases cell viability and 14-3-3η protein levels in H9C2 cardiomyocytes after anoxia/reoxygenation injury. Luteoloside blocks 3C protease activity (IC₅₀ = 0.36 mM) and reduces the cytopathic effect of enterovirus 71 in rhabdomyosarcoma cells (EC₅₀ = 0.43 mM). It inhibits the growth of hepatocellular carcinoma (HCC) cells in vitro via reduction in ROS accumulation, caspase-1 activity, and expression of the NLRP3 inflammasome and reduces the number of lung metastases in an SMMC-7721 HCC mouse xenograft model when administered at a dose of 2 mg/kg. Luteoloside also reduces acanthosis and expression of epidermal differentiation markers in a mouse model of psoriasis induced by imiquimod .

Chemical Properties

Off-white powder

Uses

Luteolin 7-Glucoside is a strong antioxidant ant radical scavenger. Used in cancer prevention.

Definition

ChEBI: A glycosyloxyflavone that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.

Cynaroside Preparation Products And Raw materials

Raw materials

Preparation Products

Cynaroside Suppliers

Global( 264)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3424	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	sales@dolonchem.com	CHINA	2972	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Chengdu GLP biotechnology Co Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58
Hubei xin bonus chemical co. LTD	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58

View Lastest Price from Cynaroside manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-09	Cynaroside 5373-11-5	US $0.00 / g	10g	98%	2	Changsha Staherb Natural Ingredients Co., Ltd.
2023-11-15	Cynaroside 5373-11-5	US $30.00-10.00 / kg	1kg	0.99	10 tons	Hebei Yanxi Chemical Co., Ltd.
2023-09-06	Cynaroside 5373-11-5	US $0.00-0.00 / KG	1KG	99%	500000kg	Hebei Guanlang Biotechnology Co., Ltd.

Cynaroside
5373-11-5
US $0.00 / g
98%
Changsha Staherb Natural Ingredients Co., Ltd.

Cynaroside
5373-11-5
US $30.00-10.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

Cynaroside
5373-11-5
US $0.00-0.00 / KG
99%
Hebei Guanlang Biotechnology Co., Ltd.

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Diosmin petunidin-3-O-glu,PETUNIDIN3-O-GLUCOSIDE ALPHA-BOSWELLIC ACID QUERCETIN-7-O-GLUCOSIDE LUTEOLIN-7,3'-DI-O-DIGLUCURONIDE

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LUTEOLIN-7-O-GLUCOSIDE 98+% luteolin7-o-glucopyranoside CYNAROSIDE LUTEOLIN-7-O-GLUCOSIDE WITH HPLC 7-β-D-Glucosylluteolin Nephrocizin Nephrocizine Luteoloside，Cynaroside，Galuteolin，Glucoluteolin Luteolin 7-β-D-glucopyranoside Luteolin 7-b-glucoside lCynaroside Daphneflavonoloside Flavopurposide LUTEOLIN-7-GLUCOSIDE hplc 2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one Luteolin 7-O-D-glucoside LUTEOLIN-7-O-GLUCOSIDE(P) Luteolin 7-beta-glucoside Luteolin-7-O-D-glucopyranoside, froM Gentiana Macrophylla Cynaroside Luteolin 7-O-D-glucoside 4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-7-(b-D-glucopyranosyloxy)-5-hydroxy- luteolin 7-O-beta-D-glucoside 2-(3,4-dihydroxyphenyl)-7-(beta-d-glucopyranosyloxy)-5-hydroxy-4h-1-benzopyr 4h-1-benzopyran-4-one,2-(3,4-dihydroxyphenyl)-7-(beta-d-glucopyranosyloxy)-5-h 7-glucoluteolin 7-glucosylluteolin luteolin7-monoglucoside Luteolin-7-O-D-glucopyranoside, 98%, from Gentiana macrophylla 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-5-hydroxy- GLUCOLUTEOLIN; LUTEOLOSIDE; CINAROSIDE; LUTEOLIN 7-GLUCOSIDE;LUTEOLIN 7-O-Β-D-GLUCOSIDE Luteolin-7-O-β-D-glucopyranoside, 98%, from Gentiana macrophylla Pall. 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one luteolin7-O-β-D-glucoside Cynaroside USP/EP/BP 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(.beta.-D-glucopyranosyloxy)-5-hydroxy- luteoloside LUTEOLIN-7-GLUCOSIDE LUTEOLIN-7-O-GLUCOSIDE Luteolin 7-O-β-D-glucopyranoside Galuteolin PETUNIDIN cinaroside glucoluteolin Luteolin 7-β-D-Glucopyranoside Cynaroside (Luteolin 7-glucoside) Luteoloside (Cynaroside) Luteoloside Luteolin 7-glucoside 5373-11-5 5375-11-5 1268-79-8 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Cofactor Tetra-substituted Flavones