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SPHINGOMYELINASE

CAS No.
9031-54-3
Chemical Name:
SPHINGOMYELINASE
Synonyms
EC 3.1.4.12;SPHINGOMYELINASE;Sphingomyelinase C;SPHINGOMYELIN PHOSPHODIESTERASE;sphingomyelinase from human placenta;SPHINGOMYELINASE FROM BACILLUS CEREUS;SPHINGOMYELINASE FROM STREPTOMYCES SP.;SPHINGOMYELIN CHOLINE PHOSPHOHYDROLASE;SPHINGOMYELINASE, STAPHYLOCOCCUS AUREUS;Native Bacillus cereus Sphingomyelinase
CBNumber:
CB4393078
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD00132362
MOL File:
Mol file
Last updated:2023-04-23 13:52:06

SPHINGOMYELINASE Properties

storage temp. 2-8°C
form lyophilized powder
FDA UNII RK0B27SV1J

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P261-P272-P280-P302+P352-P333+P313-P362+P364
Hazard Codes  B
Safety Statements  23-24/25
WGK Germany  3

SPHINGOMYELINASE price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S9396 Sphingomyelinase from Bacillus cereus buffered aqueous glycerol solution, ≥100?units/mg protein (Lowry) 9031-54-3 25units $227 2024-03-01 Buy
Sigma-Aldrich S9396 Sphingomyelinase from Bacillus cereus buffered aqueous glycerol solution, ≥100?units/mg protein (Lowry) 9031-54-3 50units $383 2024-03-01 Buy
Sigma-Aldrich S8633 Sphingomyelinase from Staphylococcus aureus buffered aqueous glycerol solution, 100-300?units/mg protein (Lowry) 9031-54-3 25units $215 2024-03-01 Buy
Sigma-Aldrich S8633 Sphingomyelinase from Staphylococcus aureus buffered aqueous glycerol solution, 100-300?units/mg protein (Lowry) 9031-54-3 50units $365 2024-03-01 Buy
Sigma-Aldrich S7651 Sphingomyelinase from Bacillus cereus lyophilized powder, ≥100?units/mg protein 9031-54-3 10units $37.32 2024-03-01 Buy
Product number Packaging Price Buy
S9396 25units $227 Buy
S9396 50units $383 Buy
S8633 25units $215 Buy
S8633 50units $365 Buy
S7651 10units $37.32 Buy

SPHINGOMYELINASE Chemical Properties,Uses,Production

Uses

sphingomyelinase is a fluid that can enhance the skin’s moistureretention properties.

Uses

Sphingomyelinase from Staphylococcus aureus has been used to:

  • induce neurotoxicity in rat cortical cultures to study the protective effects of minocycline
  • determine the concentration of sphingomyelin from serum samples
  • enhance sphingomyelinase activity to study PARK9-mediated exosome biogenesis

Uses

Sphingomyelinase from Bacillus cereus has been used:

  • in the measurement of membrane capacitance in brain slices
  • for testing and confirming its silkworm-killing activity
  • in enzyme activity assay and for elucidating its effect on hydrolysis of sphingomyelin in complex lipid mixtures

General Description

Sphingomyelinase from Bacillus cereus (Bc-Smase) is a Mg2+-containing metalloenzyme. Bacillus cereus sphingomyelinase induces hemolysis of sheep erythrocytes.

Biochem/physiol Actions

Initiates the formation of sphingomyelin-based second messengers. Activates MAPK (mitogen-activated protein kinase) and SAPKs (stress-activated protein kinases); generates ceramide from sphingomyelin.

SPHINGOMYELINASE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 24)Suppliers
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Creative Enzymes
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Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
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Shanghai Guchen Biotechnology Co., LTD 021-34675735 19147740836 1986399151@qq.com China 9849 58
EC 3.1.4.12 SPHINGOMYELINASE SPHINGOMYELINASE, STAPHYLOCOCCUS AUREUS SPHINGOMYELIN CHOLINE PHOSPHOHYDROLASE SPHINGOMYELIN PHOSPHODIESTERASE sphingomyelinase from human placenta Sphingomyelinase C SPHINGOMYELINASE FROM STAPHYLOCOCCUS*AUR EUS SPHINGOMYELINASE (SPHINGOMYELIN PHOSPHOD IESTERASE) SPHINGOMYELINASE FROM BACILLUS CEREUS SPHINGOMYELINASE FROM STREPTOMYCES SP. Sphingomyelin choline phosphohydrolase, Sphingomyelin phosphodiesterase Native Sphingomyelinase from Streptomyces sp. Native Bacillus cereus Sphingomyelinase Native Staphylococcus aureus Sphingomyelinase Sphingomyelinase from Bacillus cereus lyophilized powder, >=100 units/mg protein Sphingomyelinase from Bacillus cereus buffered aqueous glycerol solution, >=100 units/mg protein (Lowry) 9031-54-3 Lipid Metabolism Metabolomics General Metabolic Enzymes Biochemicals and Reagents Application Index BioChemical Cell Dissociation Cell Dissociation and Cell Lysis Enzymes, Inhibitors, and Substrates