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4-(2-Aminoethyl)morpholine

CAS No.
2038-03-1
Chemical Name:
4-(2-Aminoethyl)morpholine
Synonyms
2-morpholinoethan-1-amine;Morpholinoethylamine;4-MORPHOLINEETHANAMINE;2-morpholin-4-ylethanamine;2-(4-Morpholinyl)ethanamine;2-(4-Morpholinyl)ethylamine;RARECHEM AL BW 0412;LM11A 31 Impurity 1;2-Morpholinoethylami;LABOTEST-BB LT02100621
CBNumber:
CB4409865
Molecular Formula:
C6H14N2O
Molecular Weight:
130.19
MDL Number:
MFCD00006182
MOL File:
2038-03-1.mol
MSDS File:
SDS
Last updated:2023-05-25 10:25:48

4-(2-Aminoethyl)morpholine Properties

Melting point 24 °C
Boiling point 205 °C(lit.)
Density 0.992 g/mL at 25 °C(lit.)
refractive index n20/D 1.476(lit.)
Flash point 347 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Chloroform, Methanol
form Liquid After Melting
pka pK1: 4.06(+2);pK2: 9.15(+1) (25°C)
color Clear colorless to pale yellow
Water Solubility soluble
Sensitive Air Sensitive
BRN 104378
Stability Air Sensitive
InChIKey RWIVICVCHVMHMU-UHFFFAOYSA-N
CAS DataBase Reference 2038-03-1(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII T92F2H779P
NIST Chemistry Reference 4-Morpholineethanamine(2038-03-1)
EPA Substance Registry System 4-Morpholineethanamine (2038-03-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H314-H317
Precautionary statements  P260-P270-P280-P301+P312-P303+P361+P353-P305+P351+P338
Hazard Codes  C,T
Risk Statements  22-34-43-24-40-23/24/25
Safety Statements  26-36/37/39-45-22
RIDADR  UN 2735 8/PG 2
WGK Germany  2
RTECS  QD7350000
Hazard Note  Toxic
TSCA  Yes
HazardClass  8
PackingGroup  III
HS Code  29349990
Toxicity guinea pig,LD50,skin,300uL/kg (0.3mL/kg),Journal of Industrial Hygiene and Toxicology. Vol. 26, Pg. 269, 1944.
NFPA 704
2
0

4-(2-Aminoethyl)morpholine price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A55004 4-(2-Aminoethyl)morpholine 99% 2038-03-1 5G $54.5 2024-03-01 Buy
Sigma-Aldrich A55004 4-(2-Aminoethyl)morpholine 99% 2038-03-1 25G $85.7 2024-03-01 Buy
Sigma-Aldrich A55004 4-(2-Aminoethyl)morpholine 99% 2038-03-1 100G $191 2024-03-01 Buy
TCI Chemical A0883 4-(2-Aminoethyl)morpholine >98.0%(GC)(T) 2038-03-1 25g $34 2024-03-01 Buy
TCI Chemical A0883 4-(2-Aminoethyl)morpholine >98.0%(GC)(T) 2038-03-1 100g $93 2024-03-01 Buy
Product number Packaging Price Buy
A55004 5G $54.5 Buy
A55004 25G $85.7 Buy
A55004 100G $191 Buy
A0883 25g $34 Buy
A0883 100g $93 Buy

4-(2-Aminoethyl)morpholine Chemical Properties,Uses,Production

Chemical Properties

clear colorless to pale yellow liq. after melting

Uses

4-(2-Aminoethyl)morpholine is widely used in biomedical applications as this moiety serves as an important lysosome-targeting group. Some of its applications include:

  • Synthesis of the lysosome-targetable fluorescent probe for hydrogen sulfide imaging in living cells.
  • Synthesis of 1,8-naphthalimide conjugated Troger′s bases as deoxyribonucleic acid (DNA) targeting fluorescent probe.
  • Synthesis of intramolecular charge transfer-photoinduced electron transfer-fluorescence resonance energy transfer (ICT-PET-FRET) fluorescent probe for monitoring pH changes in living cells.
  • It is also used as a precursor to synthesize a variety of antimicrobial agents.

Uses

4-(2-Aminoethyl)morpholine is used as a ligand and reacts with nickel(II) nitrite to form trans-bis[4-(2-aminoethyl)morpholine]dinitronickel(II).

Definition

ChEBI: 4-2-Aminoethyl-morpholine is a member of morpholines.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 34, p. 1805, 1991 DOI: 10.1021/jm00110a008

Global( 233)Suppliers
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View Lastest Price from 4-(2-Aminoethyl)morpholine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(2-Aminoethyl)morpholine pictures 2019-07-06 4-(2-Aminoethyl)morpholine
2038-03-1
US $1.00 / kg 1kg 98% 100KG Career Henan Chemical Co
RARECHEM AL BW 0412 N-AMINOETHYL MORPHOLINE N-(2-AMINOETHYL)MORPHOLINE 1-Amino-2-morpholinoethane 4-(2-aminoethyl)-morpholin beta-Aminoaethyl-morpholin beta-Morpholinoethylamine Morpholine, 4-(2-aminoethyl)- N-(beta-Aminoethyl)morpholine N-2-Aminoethylmorfolin LABOTEST-BB LT02100621 4-(2-AMINOETHYL)MORPHOLINE 2-MORPHOLINOETHYLAMINE 2-MORPHOLIN-4-YL-ETHYLAMINE 2-(4-MORPHOLINO)ETHYLAMINE 4-Morpholineethaneamine 2-(4-MORPHOLINO)ETHYLAMINE 97% 4-(2-Aminoethyl)morpholine, 98+% 2-(4-Morpholino)ethylamine, 98+% 2-Morpholinoethylami 4-Morpholineethylamine 4-(2-AMinoethyl)Morpholine, 99% 100GR 4-(2-Aminoethyl)morpholine ,99% Morpholine-4-ethanamine 2-(N-Morpholino)ethylaMine 4-(2-Aminoethyl)morpholine > LM11A 31 Impurity 1 2-(4-Morpholinyl)ethanamine 2-(4-Morpholinyl)ethylamine Morpholinoethylamine 4-MORPHOLINEETHANAMINE 2-morpholinoethan-1-amine 2-morpholin-4-ylethanamine 4-Morpholineethanamine (9CI, ACI) 2038-03-1 2038-3-1 203-83-1 AMINE Building Blocks Heterocyclic Building Blocks Morpholines Building Blocks Chemical Synthesis Heterocyclic Building Blocks Morpholines/Thiomorpholines Building Blocks Heterocyclic Building Blocks Morpholines