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Dihydrocoumarin

Dihydrocoumarin Structure
Dihydrocoumarin structure
CAS No.
119-84-6
Chemical Name:
Dihydrocoumarin
Synonyms
3,4-DIHYDROCOUMARIN;CHROMAN-2-ONE;HYDROCOUMARIN;3,4-DIHYDRO-2H-1-BENZOPYRAN-2-ONE;2H-1-Benzopyran-2-one, 3,4-dihydro-;MELILOTIN;3,4-Dihydro-1-benzopyran-2-one;Tonkamel;FEMA 2381;MELILOTOL
CBNumber:
CB4413174
Molecular Formula:
C9H8O2
Molecular Weight:
148.16
MDL Number:
MFCD00006881
MOL File:
119-84-6.mol
Last updated:2025-12-02 14:41:18
Product description Number Pack Size Price
Dihydrocoumarin ≥99%, FCC, FG W238104 1 unit $53.48
Dihydrocoumarin ≥99%, FCC, FG W238104 1 unit $53.48
Dihydrocoumarin ≥99%, FCC, FG W238104 1kg $79.32
Dihydrocoumarin ≥99%, FCC, FG W238104 5kg $223
Dihydrocoumarin ≥99%, FCC, FG W238104 10Kg $371
More product size
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Dihydrocoumarin Properties

Melting point 24-25 °C (lit.)
Boiling point 272 °C (lit.)
Density 1.169 g/mL at 25 °C (lit.)
vapor pressure 13.6kPa at 20℃
refractive index n20/D 1.556(lit.)
FEMA 2381 | DIHYDROCOUMARIN
Flash point >230 °F
storage temp. Sealed in dry,2-8°C
solubility Chloroform, Methanol (Sparingly)
form Solid
Specific Gravity 1.169
color Colourless to Off-White
Odor at 10.00 % in dipropylene glycol. sweet tonka coumarinic coconut herbal cinnamon balsamic
Odor Type tonka
biological source synthetic
Water Solubility insoluble
JECFA Number 1171
BRN 4584
LogP 1.82 at 25℃
Toxicology and Carcinogenesis Toxicology and Carcinogenesis Studies of 3,4-Dihydrocoumarin (CASRN 119-84-6) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
Substances Added to Food (formerly EAFUS) DIHYDROCOUMARIN
CAS DataBase Reference 119-84-6(CAS DataBase Reference)
EWG's Food Scores 4-7
FDA UNII NM5K1Y1BT2
NIST Chemistry Reference 2H-1-Benzopyran-2-one, 3,4-dihydro-(119-84-6)
EPA Substance Registry System 3,4-Dihydrocoumarin (119-84-6)
UNSPSC Code 12352200
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P261-P264-P270-P280-P301+P312-P302+P352
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  MW5775000
TSCA  Yes
HS Code  29322980
Hazardous Substances Data 119-84-6(Hazardous Substances Data)
Toxicity The acute oral LD50 value in rats was reported as 1.65 g/kg (1.47-1.83 g/ kg) (Moreno, 1972a). The acute dermal LD50 value in rabbits was reported as > 5 g/kg (Moreno, 1972b).
NFPA 704
1
2 0

Dihydrocoumarin price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W238104 Dihydrocoumarin ≥99%, FCC, FG 119-84-6 1 unit $53.48 2025-07-31 Buy
Sigma-Aldrich W238104 Dihydrocoumarin ≥99%, FCC, FG 119-84-6 1 unit $53.48 2025-07-31 Buy
Sigma-Aldrich W238104 Dihydrocoumarin ≥99%, FCC, FG 119-84-6 1kg $79.32 2025-07-31 Buy
Sigma-Aldrich W238104 Dihydrocoumarin ≥99%, FCC, FG 119-84-6 5kg $223 2025-07-31 Buy
Sigma-Aldrich W238104 Dihydrocoumarin ≥99%, FCC, FG 119-84-6 10Kg $371 2025-07-31 Buy
Product number Packaging Price Buy
W238104 1 unit $53.48 Buy
W238104 1 unit $53.48 Buy
W238104 1kg $79.32 Buy
W238104 5kg $223 Buy
W238104 10Kg $371 Buy

Dihydrocoumarin Chemical Properties,Uses,Production

Description

With a sweet, creamy, and herbal, fragrance, with a slightly burnt taste, dihydrocoumarin (DHC) is used as a flavoring agent in food, tobacco, soap, and perfume, etc. Its exotic flavor is well suited for caramel, nuts, dairy, vanilla, tropical fruit, and alcohol. It is a eukaryotic metabolite found in tonka beans grown in northern South America, from which it was isolated as early as the 1820s, as well as sweet clover. Other uses include as an organic solvent and pharmaceutical intermediary. It has been shown to influence the epigenetic process of human cells in vitro.

Sources

http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16151
http://www.bojensen.net/EssentialOilsEng/EssentialOils29/EssentialOils29.htm#Tonka
https://books.google.kg/books?id=pUEqBgAAQBAJ&pg=PA427&lpg=PA427&dq=dihydrocoumarin+uses&source=bl&ots=HTZrffvsXu&sig=GPGKqrMRXQaRJ-qgHk7aULeBmGw&hl=en&sa=X&redir_esc=y#v=onepage&q=dihydrocoumarin%20uses&f=false
https://products.symrise.com/aroma-molecules/product-search/dihydrocoumarin/action/pdf/
http://www.lookchem.com/3-4-Dihydrocoumarin/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1315280/

Chemical Properties

Dihydrocoumarin has an odor similar to coumarin at room temperature or reminiscent of nitrobenzene at higher temperature. It has a burning taste.

Chemical Properties

Dihydrocoumarin forms colorless crystals (mp 24°C) with a sweet, herbal odor. Dihydrocoumarin is prepared by hydrogenation of coumarin, for example, in the presence of a Raney nickel catalyst. Another process employs the vapor-phase dehydrogenation of hexahydrocoumarin in the presence of Pd or Pt-Al2O3 catalysts . Hexahydrocoumarin is prepared by cyanoethylation of cyclohexanone and hydrolysis of the nitrile group, followed by ring closure to the lactone.

Occurrence

Reported found in Melilotus officinalis, from which it may be extracted by water distillation.

Uses

Hydrocoumarin can be used as a reagent to prepare splitomicin analogs as inhibitors of Sir2.

Uses

Dihydrocoumarin may be used as an analytical reference standard for the determination of the analyte in guaco extracts and pharmaceutical preparations, and various plant extracts by chromatography-based techniques and capillary electrophoresis.

Definition

ChEBI: A chromanone that is the 3,4-dihydro derivative of coumarin.

Preparation

Dihydrocoumarin is synthesized by reduction of coumarin under pressure in the presence of nickel at 160 to 200°C or in the presence of Pd-BaSO4 in alcoholic solution.

Synthesis Reference(s)

Tetrahedron Letters, 37, p. 4555, 1996 DOI: 10.1016/0040-4039(96)00902-1

General Description

Viscous, almost colorless liquid, solidifying in the cold, melting at 23° C. Sp. Gr. 1.19. B.P. 272° C. Slightly soluble in water, soluble in alcohol, miscible with oils.
Sweet-herbaceous, nutlike, haylike odor, usually described as "coumannic" or "tobacco-like".

Air & Water Reactions

Solutions of the chemical in water are stable for less than two hours. Insoluble in water.

Reactivity Profile

Hydrocoumarin is a lactone (behaves as an ester). Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. Hydrocoumarin may hydrolyze under alkaline or acidic conditions.

Fire Hazard

Hydrocoumarin is combustible.

Biochem/physiol Actions

Taste at 10 ppm

Dihydrocoumarin synthesis

83-33-0
119-84-6
Synthesis of Dihydrocoumarin from 1-Indanone

Dihydrocoumarin Preparation Products And Raw materials

Raw materials

Coumarin trans-Cinnamic acid 2-(3-HYDROXY-PROPYL)-PHENOL 3-Phenylpropionic acid

Preparation Products

2H-1-Benzopyran-2-one, 3,4-dihydro-7-hydroxy-4-(1-naphthalenyl)- 4-METHOXY-1-INDANONE 3-(2-METHOXY-PHENYL)-PROPIONALDEHYDE 2H-1-Benzopyran-6-sulfonyl chloride, 3,4-dihydro-2-oxo-

Dihydrocoumarin Suppliers

Global( 530)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8768 58
Nanjing Deda New Material Technology Co., Ltd 		+8613223293093 bella@njdeda.com China 80 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325 sales1@chuanghaibio.com China 5249 58
Hebei Fengjia New Material Co., Ltd 		+86-0311-87836622 +86-18712993135 sales01@tairunfaz.com China 8051 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615531151365 mina@chuanghaibio.com China 18126 58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		+8613343047651 admin@zlchemi.com China 3692 58
Shandong Deshang Chemical Co., Ltd. 		+86-0531-8875-2665 +8613153039501 info@deshangchem.com China 661 58
JINING XINHE CHEMICAL CO., LTD 		+8615318402391 sales@xinhepharma.com China 809 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21614 55
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3619 58
Supplier Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		58
Nanjing Deda New Material Technology Co., Ltd 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Hebei Fengjia New Material Co., Ltd 		58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		58
Shandong Deshang Chemical Co., Ltd. 		58
JINING XINHE CHEMICAL CO., LTD 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Zheyan Biotech Co., Ltd. 		58

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View Lastest Price from Dihydrocoumarin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Dihydrocoumarin pictures 2025-12-02 Dihydrocoumarin
119-84-6
 US $29.00 / mL 98.46% 10g TargetMol Chemicals Inc.
Cinnamic acid pictures 2025-11-27 Cinnamic acid
119-84-6
 US $10.00 / KG 1KG 99% 5tons Hebei Chuanghai Biotechnology Co., Ltd
Dihydrocoumarin pictures 2025-06-27 Dihydrocoumarin
119-84-6
 US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
  • Cinnamic acid pictures
  • Cinnamic acid
    119-84-6
  • US $10.00 / KG
  • 99%
  • Hebei Chuanghai Biotechnology Co., Ltd
  • Dihydrocoumarin pictures
  • Dihydrocoumarin
    119-84-6
  • US $0.00-0.00 / KG
  • 99%
  • Hebei Chuanghai Biotechnology Co., Ltd

Dihydrocoumarin Spectrum

Cinnamic acid(119-84-6)MSCinnamic acid(119-84-6)1HNMRCinnamic acid(119-84-6)13CNMRCinnamic acid(119-84-6)IR1Cinnamic acid(119-84-6)Raman

119-84-6(Dihydrocoumarin)Related Search:

Nickel Potassium cinnamate Ethanol Sodium bicarbonate URANIUM
Barium hydroxide Metronidazole Dihydrocoumarin 4-HYDROXY MEPHENYTOIN 3-Phenylpropionic acid
Vanillin 6,7-DIMETHOXY-4-METHYL-CHROMAN-2-ONE 3-[(Z)-ANILINOMETHYLIDENE]-2H-CHROMENE-2,4-DIONE 3-[(Z)-(3-CHLOROANILINO)METHYLIDENE]-2H-CHROMENE-2,4-DIONE 3-(2,6-DICHLOROPHENYL)-3A,9B-DIHYDRO-4H-CHROMENO[3,4-D]ISOXAZOL-4-ONE
4-(4-CHLOROPHENYL)-5,7-DIHYDROXY-2-CHROMANONE 3-((Z)-[4-(TRIFLUOROMETHYL)ANILINO]METHYLIDENE)-2H-CHROMENE-2,4-DIONE Hydrocoumarin, 6-acetamido-3-(1-pyrrolidinylcarbonyl)-

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AKOS 222-08 Hydrocoumarin,6-methyl-4phenyl-3,4dihydro-6-methyl-4-phenyl-2h-benzopyran-2-one Dihydrocoumarin 1g [119-84-6] Dihydrocoumarin,3,4-Dihydro-1-benzopyran-2-one, Benzodihydropyrone, Hydrocoumarin DIHYDROCOUMARIN,3,4-(RG) 3,4-dihydrobenzopyran-2-one DIHYDROCOUMARIN FOR SYNTHESIS DihydrocouMarin 99% 2-Chromanone 2-oxo-chroma 3,4-dihydro-2h-1-benzopyran-2-on 3,4-dihydro-coumari 3,4-Dihydroxycoumarin Benzopyranone, dihydro- Chroman, 2-oxo- Coumarin, 3,4-dihydro- Hydrocinnamic acid, o-hydroxy-, delta-lactone 1,2-BENZODIHYDROPYRONE BENZODIHYDROPYRONE DIHYDROBENZENOPYRONE DIHYDROBENZOPYRONE DIHYDROCOUMARIN DIHYDROCOUMARIN,3,4- FEMA 2381 MELILOTINE MELILOTOL meliloticlactone NCI-C55890 o-hydroxy-hydrocinnamicacidelta-lactone oxochroman USAF do-12 usafdo-12 3,4-Dihydroqoumarin 2H-1-BENZOPYRAN-2-ONE,3,4-D 8-Azabicyclo[3.2.1]octan-3-one, 8-(phenylmethyl)- 4H-1-Benzopyran-2(3H)-one Dihydrocoumarin,99% 3,4-Dihydro-1-benzopyran-2-one, Benzodihydropyrone, Hydrocoumarin Tonkamel DIHYDROCOUMARIN 99+% FCC Two hydrogen 3,4-Dihydrocoumarin > Dihydrocoumarin@1000 μg/mL in Acetone Cinnamic acid USP/EP/BP Meliotine Coumarin, 3, 4-Dihydro- 3, 4-Dyhydrocoumarin CAS 119-84-6 3,4-dihydrochromen-2-one 3,4-Dihydro-1-benzopyran-2-one 3,4-DIHYDRO-2H-1-BENZOPYRAN-2-ONE 3,4-DIHYDROCOUMARIN CHROMAN-2-ONE HYDROCOUMARIN MELILOTIN 2H-1-Benzopyran-2-one, 3,4-dihydro- ihydrocoumarin Dihydrocoumarin, 10 mM in DMSO Natural dihydrocoumarin 119-84-6 Heterocyclic Building Blocks