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2-Benzofurancarboxylic acid ethyl ester

CAS No.
3199-61-9
Chemical Name:
2-Benzofurancarboxylic acid ethyl ester
Synonyms
Ethyl CouMarilate;RARECHEM AL BI 0556;Ethyl 2-benzofurancarboxylate;ethyl benzofuran-2-carboxylate;Ethyl 1-benzofuran-2-carboxylate;Ethyl benzo[b]furan-2-carboxylate;Ethyl benzo[b]furan-2-carboxylate 97%;BENZOFURAN-2-CARBOXLIC ACID ETHYL ESTER;BENZOFURAN-2-CARBOXYLIC ACID ETHYL ESTER;2-BENZOFURANCARBOXYLIC ACID, ETHYL ESTER
CBNumber:
CB4414494
Molecular Formula:
C11H10O3
Molecular Weight:
190.2
MDL Number:
MFCD03094950
MOL File:
3199-61-9.mol
MSDS File:
SDS
Last updated:2022-12-30 16:20:48

2-Benzofurancarboxylic acid ethyl ester Properties

Melting point 166-170℃
Boiling point 105°/0.1mm
Density 1.1656
refractive index 1.5640 (estimate)
Flash point >110℃
storage temp. 2-8°C
CAS DataBase Reference 3199-61-9(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P305+P351+P338
Hazard Codes  T
WGK Germany  3
HazardClass  IRRITANT
HS Code  2932190090

2-Benzofurancarboxylic acid ethyl ester price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 763632 Ethyl benzofuran-2-carboxylate 97% 3199-61-9 1g $30.2 2023-06-20 Buy
TRC E904900 EthylCoumarilate 3199-61-9 2.5g $160 2021-12-16 Buy
SynQuest Laboratories 2H23-1-X1 Ethylbenzo[b]furan-2-carboxylate 97% 3199-61-9 1g $108 2021-12-16 Buy
Biosynth Carbosynth FB33202 Benzofuran-2-carboxylic acid ethyl ester 3199-61-9 500mg $130 2021-12-16 Buy
AK Scientific N531 Benzofuran-2-carboxylicacidethylester 3199-61-9 10g $134 2021-12-16 Buy
Product number Packaging Price Buy
763632 1g $30.2 Buy
E904900 2.5g $160 Buy
2H23-1-X1 1g $108 Buy
FB33202 500mg $130 Buy
N531 10g $134 Buy

2-Benzofurancarboxylic acid ethyl ester Chemical Properties,Uses,Production

Uses

Ethyl Coumarilate has been used as a reactant for the preparation of benzofuropyridines that have a high affinity for the α2-adrenoceptor.

Preparation

Synthesis of ethyl benzofuran-2-carboxylate: Salicylaldehyde (20.0 mL, 0.164 mol) and diethyl bromomalonate (40.0 mL, 0.168 mol) in ethyl methyl ketone (40.0 mL, 0.555 mol) was treated with anhydrous potassium carbonate (20.0 g,0.869 mol). The reaction mixture was refluxed for 18 h on steam bath. Ethyl methyl ketone was distilled off under reduced pressure and the residue formed was dissolved in 400 mL of water and cooled in an ice-bath. It was acidified with dil H2SO4. The product formed was extracted with 25 mL portion of solvent ether twice and the extract was washed with sodium bicarbonate solution. It was dried over calcium chloride. Solvent was removed and the residue ethyl benzofuran-2-carboxylate was dried.

Synthesis Reference(s)

Tetrahedron Letters, 27, p. 6315, 1986 DOI: 10.1016/S0040-4039(00)87796-5

2-Benzofurancarboxylic acid ethyl ester Preparation Products And Raw materials

Global( 103)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29827 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196 sale04@alfachem.cn China 12337 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com CHINA 52867 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 50002 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 132020 58
Mainchem Co., Ltd. +86-0592-6210733 sale@mainchem.com China 32360 55
Chemwill Asia Co.,Ltd. 86-21-51086038 chemwill_asia@126.com CHINA 23931 58

View Lastest Price from 2-Benzofurancarboxylic acid ethyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Benzofurancarboxylic acid ethyl ester pictures 2020-01-10 2-Benzofurancarboxylic acid ethyl ester
3199-61-9
US $7.00 / KG 1KG 99% 100KG Career Henan Chemical Co
BENZOFURAN-2-CARBOXYLIC ACID ETHYL ESTER BENZOFURAN-2-CARBOXLIC ACID ETHYL ESTER Ethyl benzo[b]furan-2-carboxylate 97% RARECHEM AL BI 0556 2-BENZOFURANCARBOXYLIC ACID, ETHYL ESTER ethyl benzofuran-2-carboxylate Ethyl 2-benzofurancarboxylate 2-(Ethoxycarbonyl)benzo[b]furan, Ethyl 1-benzofuran-2-carboxylate Ethyl CouMarilate Ethyl 1-benzofuran-2-carboxylate 1-isobenzofurancarboxylic acid ethyl ester Ethyl benzo[b]furan-2-carboxylate 3199-61-9 Miscellaneous