3-HYDROXYFLAVONE
- CAS No.
- 577-85-5
- Chemical Name:
- 3-HYDROXYFLAVONE
- Synonyms
- FLAVONOL;3-HF;3-FLAVONOL;FLAVON-3-OL;AURORA 20058;3-hydroxy-flavon;3-HYDROXYFLAVONE;HYDROXYFLAVONE, 3-;TIMTEC-BB SBB000767;Flavone, 3-hydroxy-
- CBNumber:
- CB4414838
- Molecular Formula:
- C15H10O3
- Molecular Weight:
- 238.24
- MDL Number:
- MFCD00006832
- MOL File:
- 577-85-5.mol
- MSDS File:
- SDS
| Melting point | 171-172 °C (lit.) |
|---|---|
| Boiling point | 320.83°C (rough estimate) |
| Density | 1.2653 (rough estimate) |
| refractive index | 1.5740 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO: 1 mg/ml |
| form | powder to crystal |
| pka | 8.80±0.20(Predicted) |
| color | White to Yellow to Green |
| Water Solubility | Insoluble in water. Soluble in N,N-DMF and ethanol. |
| BRN | 15789 |
| InChIKey | HVQAJTFOCKOKIN-UHFFFAOYSA-N |
| LogP | 3.477 (est) |
| CAS DataBase Reference | 577-85-5(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | ZTG9LSS5QH |
| EPA Substance Registry System | 4H-1-Benzopyran-4-one, 3-hydroxy-2-phenyl- (577-85-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LK8650000 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29322090 | |||||||||
| NFPA 704 |
|
3-HYDROXYFLAVONE price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H4280 | 3-Hydroxyflavone ≥98% | 577-85-5 | 5g | $124 | 2024-03-01 | Buy |
| TCI Chemical | H0379 | 3-Hydroxyflavone >98.0%(HPLC)(T) | 577-85-5 | 1g | $40 | 2024-03-01 | Buy |
| TCI Chemical | H0379 | 3-Hydroxyflavone >98.0%(HPLC)(T) | 577-85-5 | 10g | $192 | 2024-03-01 | Buy |
| Alfa Aesar | A18110 | 3-Hydroxyflavone, 98+% | 577-85-5 | 1g | $30.65 | 2024-03-01 | Buy |
| Alfa Aesar | A18110 | 3-Hydroxyflavone, 98+% | 577-85-5 | 5g | $109 | 2024-03-01 | Buy |
3-HYDROXYFLAVONE Chemical Properties,Uses,Production
Chemical Properties
yellow fluffy powder
Uses
3-Hydroxyflavone is a reactant involved in studies of photochemically-induced dioxygenase-type CO-release reactivity; phase-transfer protection and deprotection of hydroxychromones; and O-methylation with di-Me carbonate. As a reactant it is involved in the synthesis of biologically active molecules including 2-chloropyridine derivatives for studies of antitumor agents and telomerase inhibitors; dihydrochromenopyrazines and chromenoquinoxalines. It is also involved in studies of its electrochemical properties using voltammetric methodologies.
Uses
Reactant involved in:• ;Studies of photochemically-induced dioxygenase-type CO-release reactivity1• ;Phase-transfer protection and deprotection of hydroxychromones2• ;O-methylation with di-Me carbonate3Reactant involved in the synthesis of biologically active molecules including:• ;2-Chloropyridine derivatives for studies of antitumor agents and telomerase inhibitors4• ;Dihydrochromenopyrazines and chromenoquinoxalines5Involved in studies of its electrochemical properties using voltammetric methodologies6
Definition
ChEBI: A monohydroxyflavone that is the 3-hydroxy derivative of flavone.
Synthesis Reference(s)
Tetrahedron Letters, 25, p. 5561, 1984 DOI: 10.1016/S0040-4039(01)81626-9
Purification Methods
Recrystallise it from MeOH (m 169.5-170o), EtOH, aqueous EtOH (m 167o) or hexane. It has also been purified by repeated sublimation under high vacuum, and dried at high vacuum pumping for at least one hour [Bruker & Kelly J Phys Chem 91 2856 1987]. [Beilstein 17 H 527, 17 I 268, 17 II 498, 17 III/IV 6428.]
3-HYDROXYFLAVONE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81148696 +8615536356810 | 1047@dideu.com | China | 3408 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12468 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12382 | 58 |
| GLR Innovations | +91 9891111994 | info@glrgroup.in | India | 4542 | 58 |
View Lastest Price from 3-HYDROXYFLAVONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-07-08 | 3-HYDROXYFLAVONE
577-85-5
|
US $8890.00 / KG | 1KG | 98.0% | 1T | Shaanxi Dideu Medichem Co. Ltd | |
 |
2019-07-06 | 3-HYDROXYFLAVONE
577-85-5
|
US $1.00 / kg | 1g | 99% | 100KG | Career Henan Chemical Co |
-
- 3-HYDROXYFLAVONE
577-85-5
- US $8890.00 / KG
- 98.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 3-HYDROXYFLAVONE
577-85-5
- US $1.00 / kg
- 99%
- Career Henan Chemical Co