ChemicalBook >> CAS DataBase List >>3-Ethynylaniline

3-Ethynylaniline

3-Ethynylaniline structure

CAS No.: 54060-30-9

Chemical Name:: 3-Ethynylaniline

Synonyms: 3-ETHYNYLANILINE;3-ETHYNYL-PHENYLAMINE;3-EthynylbenzaMine;M-AMINOPHENYL ACETYLENE;SOLI-006;3-Ethynyl;Erlotinib-8;Erlotinib INT;3-Ethynlaniline;m-Ethnylaniline

CBNumber:: CB4417819

Molecular Formula:: C8H7N

Molecular Weight:: 117.15

MDL Number:: MFCD00014779

MOL File:: 54060-30-9.mol

MSDS File:: SDS

Last updated:2024-04-16 16:23:18

Request For Quotation

3-Ethynylaniline Properties

Melting point	27°C
Boiling point	92-93 °C (2 mmHg)
Density	1.04
refractive index	1.614-1.616
Flash point	138 °F
storage temp.	2-8°C
solubility	Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly)
form	Liquid
pka	3.67±0.10(Predicted)
color	Clear yellow to brown
Specific Gravity	1.12
Water Solubility	Insoluble in water.
BRN	2935417
Stability	Light Sensitive
InChIKey	NNKQLUVBPJEUOR-UHFFFAOYSA-N
CAS DataBase Reference	54060-30-9(CAS DataBase Reference)
FDA UNII	DU8GFZ5KGE
NIST Chemistry Reference	M-aminophenylacetylene(54060-30-9)
EPA Substance Registry System	Benzenamine, 3-ethynyl- (54060-30-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS07

Signal word

Warning

Hazard statements

H226-H315-H319-H335

Precautionary statements

P210-P302+P352-P305+P351+P338

Hazard Codes

Xi,F

Risk Statements

36/37/38

Safety Statements

26-36-37/39-36/37

RIDADR

UN 1993 3/PG 3

WGK Germany

TSCA

Yes

HazardClass

PackingGroup

Ⅲ

HS Code

29214990

NFPA 704

	2
1		0

3-Ethynylaniline price More Price(43)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	498289	3-Ethynylaniline ≥98%	54060-30-9	5g	$61.2	2024-03-01	Buy
TCI Chemical	A1122	3-Ethynylaniline >98.0%(GC)	54060-30-9	10g	$105	2021-12-16	Buy
TCI Chemical	A1122	3-Ethynylaniline >98.0%(GC)	54060-30-9	25g	$193	2024-03-01	Buy
Alfa Aesar	L20124	3-Aminophenylacetylene, 98%	54060-30-9	5g	$71.65	2024-03-01	Buy
Alfa Aesar	L20124	3-Aminophenylacetylene, 98%	54060-30-9	25g	$223.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
498289	5g	$61.2	Buy
A1122	10g	$105	Buy
A1122	25g	$193	Buy
L20124	5g	$71.65	Buy
L20124	25g	$223.65	Buy

3-Ethynylaniline Chemical Properties,Uses,Production

Chemical Properties

Clear yellowish to brown liquid

Uses

3-Aminophenylacetylene is used as a pharmaceutical intermediate.

Uses

Reagent in the preparation of a labelled metabolite of Erlotinib (E625000).

Application

3-Ethynylaniline may be used in the synthesis of the following benzoxazine monomers: bis{4-[3-(3-ethynylphenyl)(2H,4Hbenzo[3,4-e]1,3-oxazin-6-yloxy)]phenyl}phenylphosphino-1-one, [3-(3-ethynylphenyl)(2H,4Hbenzo[3,4-e]1,3-oxazaperhydroin-6-yl)][3-(3-ethynylphenyl)(2H,4H-benzo[3,4-e]1,3-oxazin-6-yl)]phenylphosphino-1-one, and bis[3-(3-ethynylphenyl)(2H,4Hbenzo[3,4-e]1,3-oxazin-6-yl)oxy]phenylphosphino-1-one.
It may be used: To synthesize succin(m-ethynyl)dianilide and sebaco(m-ethynyl)dianilide. As a reagent in the multi-step synthesis of erlotinib hydrochloride. To prepare 3-(3-ethynylphenyl)-6-methyl-2H, 4H-benzo[e]1,3-oxazine. To prepare 3-[3-(4-acetylamino-benzyl)-[1,2,4]oxadiazol-5- yl]-N-(3-ethynyl-phenyl)-propionamide.

General Description

3-Ethynylaniline is a terminal alkyne that can be prepared by the reduction of 3-ethylnylnitrobenzene.

3-Ethynylaniline synthesis

Synthesis of 3-Ethynylaniline from 4-(3-AMINOPHENYL)-2-METHYL-3-BUTYN-2-OL

3-Ethynylaniline Preparation Products And Raw materials

Raw materials

Stannous chloride dihydrate Hydrazinium hydroxide solution Ethanol Iron chloride hexahydrate 3-NITROPHENYLACETYLENE

Activated carbon

1of2

Preparation Products

Erlotinib (3aR,6aR)-N-(4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)-1-methylhexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxamide 3-Vinylaniline Benzenamine, 3-ethynyl-N-methyl- (9CI) 3-(2H-1,2,3-triazol-4-yl)aniline

3-Ethynylaniline Suppliers

Global( 607)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Neostar United (Changzhou) Industrial Co., Ltd.	+86-519-519-85557386	marketing1@neostarunited.com	China	8349	58
Wuhan Mayue Longteng Technology Development Co., Ltd.	+undefined15171477138	helen.yan@lantu-tech.com	China	287	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12457	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7613	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
Anqing Chico Pharmaceutical Co., Ltd.	15380796838	chloewu@chicopharm.cn	CHINA	341	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58

Supplier	Advantage
Neostar United (Changzhou) Industrial Co., Ltd.	58
Wuhan Mayue Longteng Technology Development Co., Ltd.	58
Hebei Mojin Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
Anqing Chico Pharmaceutical Co., Ltd.	58
career henan chemical co	58

View Lastest Price from 3-Ethynylaniline manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-16	3-Ethynylaniline 54060-30-9	US $5.00-0.10 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2023-12-14	3-Aminophenylacetylene 54060-30-9	US $0.00-0.00 / kg	1kg	98%(HPLC)	2000kg/Year	Nanjing Fred Technology Co., Ltd
2023-09-06	3-Aminophenylacetylene 54060-30-9	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd

3-Ethynylaniline
54060-30-9
US $5.00-0.10 / KG
99%
Henan Fengda Chemical Co., Ltd

3-Aminophenylacetylene
54060-30-9
US $0.00-0.00 / kg
98%(HPLC)
Nanjing Fred Technology Co., Ltd

3-Aminophenylacetylene
54060-30-9
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

3-Ethynylaniline Spectrum

3-Aminophenylacetylene(54060-30-9)MS 3-Aminophenylacetylene(54060-30-9)IR1

54060-30-9(3-Ethynylaniline)Related Search:

4-Aminobenzoic acid 2-BENZOYLACETANILIDE Aniline Methyl anthranilate Diphenylamine

3-Aminobenzenesulfonamide Sulfanilic acid Metanilic acid Acetylene Sulfanilamide

p-Anisidine 2-Aminobenzaldehyde Diphenylacetylene Phenylacetylene N,N-Dimethylaniline

Benzidine EMERALDINE BASE POLYANILINE 6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone

1of4

M-ETHYNYLANILINE 3-AMINOPHENYLACETYLENE 3-ETHYNYLBENZENEAMINE Benzenamine, 3-ethynyl- 3-ethynyl-benzenamin (3-Ethynylphenyl)aMine-d4 (M-AMinophenyl)acetylene-d4 1-AMino-3-ethynylbenzene-d4 3-AMino-1-ethynylbenzene-d4 3-Ethynylaniline-d4 3-EthynylbenzenaMine-d4 M-Ethynylaniline-d4 Erlotinib INT Erlotinib iMpurity F Erlotinib Impurity (3-Ethynylailine) 3-Ethynyl aniline or (3-aMinophenylacetylene) 3-AMinophenylacetylene(3-Ethynylaniline) 3-Ethynylailine Hydrochloride 2 RE-EXPORT OF 3-ETHYNYLANILINE 3-Ethynyl aniline (3-aminophenylacetylene) 3-AMINOPHENYLACETYLEN 3-Aminophenylacetylene98% Benzenamine, 3-ethynyl- (9CI) 3-AMINOPHENYLACETYLENE 99+% 3-Ethynyl 3-ethynylbenzenamine 3-Ethynlaniline 1-Amino-3-ethynylbenzene 1-Ethynyl-3-aminobenzene m-Ethnylaniline 3-Ethynylaniline ,98% 3-AMinophenylacetylene, 98% 25GR 3-AMinophenylacetylene, 98% 5GR 3-Ethynylaniline HC 3-Acetylenylaniline-d4 3-AMino-1-ethynylbenzene 3-aminophenylacetylene M-ETHYNYLANILINE SOLI-006 Erlotinib Impurity 42 Erlotinib Hydrochloride Impurity P Erlotinib Hydrochloride iMpurity 29 Erlotinib-8 3-Ethynylaniline > 3- Acetylene phenylamine Erlotinib Impurity 47 (3-Ethynylailine) High quality 3-Aminophenylacetylene 3-AMINOPHENYLACETYLENE (M-APA)54060-30-9 3-Aminophenylacetylene ISO 9001：2015 REACH 3-Ethynylaniline (Erlotinib Impurity) Erlotinib impurities408 Azilsartan medoxomil impurity250 M-AMINOPHENYL ACETYLENE 3-ETHYNYL-PHENYLAMINE 3-ETHYNYLANILINE 3-EthynylbenzaMine 54060-30-9 Reagents for Conducting Polymer Research Acid Anhydrides, etc. (Reagents for Conducting Polymer Research)