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Levosulpiride

Levosulpiride Structure
Levosulpiride structure
CAS No.
23672-07-3
Chemical Name:
Levosulpiride
Synonyms
Levosulpride;l-Form;rv-12309;Levopride;levopraid;l-Sulpirid;levosupride;l-Sulpiride;LEVOSULPIRIDE;(S)-(-)-Sulpir
CBNumber:
CB4422019
Molecular Formula:
C15H23N3O4S
Molecular Weight:
341.43
MDL Number:
MFCD00055220
MOL File:
23672-07-3.mol
MSDS File:
SDS
Last updated:2024-04-17 18:50:11
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Levosulpiride Properties

Melting point 183-186 °C(lit.)
Density 1.236±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMF (Slightly), DMSO (Slightly), Methanol (Slightly)
pka 9.98±0.60(Predicted)
color White to Off-White
Merck 14,8989
InChIKey BGRJTUBHPOOWDU-NSHDSACASA-N
CAS DataBase Reference 23672-07-3(CAS DataBase Reference)
FDA UNII JTG7R315LK
ATC code N05AL07

SAFETY

Risk and Safety Statements

RIDADR  3077
WGK Germany  3
RTECS  BZ3400100
HS Code  29350090
Toxicity LD50 oral in rabbit: > 1500mg/kg
NFPA 704
0
1 0

Levosulpiride price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S7771 (S)-(?)-Sulpiride ≥98% (titration) 23672-07-3 5g $96.1 2024-03-01 Buy
Sigma-Aldrich 34002 (S)-(−)-Sulpiride VETRANAL?, analytical standard 23672-07-3 100mg $145 2024-03-01 Buy
Sigma-Aldrich 5.05626 (S)-Sulpiride - CAS 23672-07-3 - Calbiochem 23672-07-3 100mg $82.2 2022-05-15 Buy
TCI Chemical I0821 (S)-(-)-Sulpiride >98.0%(HPLC)(T) 23672-07-3 5g $108 2024-03-01 Buy
TCI Chemical I0821 (S)-(-)-Sulpiride >98.0%(HPLC)(T) 23672-07-3 25g $271 2024-03-01 Buy
Product number Packaging Price Buy
S7771 5g $96.1 Buy
34002 100mg $145 Buy
5.05626 100mg $82.2 Buy
I0821 5g $108 Buy
I0821 25g $271 Buy

Levosulpiride Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

(S)-(?)-Sulpiride was used to study the effect of dopamine D2 receptor function on activation of KCNQ potassium channels10 and on depression-like behavior in ovariectomized female rats.11

Uses

dopamine receptor antagonists

Uses

Dopamine D2 and D3-receptor antagonist. Antipsychotic; antidepressant; antiemetic.

Definition

ChEBI: An optically active form of sulpiride having (S)-configuration. The active enantiomer of the racemic drug sulpiride. Selective D2-like dopamine antagonist (Ki values are ~ 0.015. ~ 0.013, 1, ~ 45 and ~ 77 muM at D2, D3, D4, 1 and D5 receptors respectively).

General Description

(S)-(?)-Sulpiride is a levorotatory enantiomer of sulpiride, which shows greater central antidopaminergic activity, antiemetic and antidyspeptic effects. It is also used as a therapeutic drug for the treatment of depression and somatoform disorders.

Biological Activity

Active enantiomer. Selective D 2 -like dopamine antagonist (K i values are ~ 0.015. ~ 0.013, 1, ~ 45 and ~ 77 μ M at D 2 , D 3 , D 4 , D 1 and D 5 receptors respectively).

Biochem/physiol Actions

(S)-(?)-Sulpiride or Levosulpiride blocks the inhibitory enteric D2 receptors (neuronal and muscular). It has prokinetic activity and is effective in the treatment of functional dyspepsia and gastroparesis in insulin-dependent diabetes mellitus patients.7,8 Since dopamine controls human sexual function, (S)-(?)-Sulpiride is reportedly effective in treatment of erectile dysfunctions.9

storage

Room temperature

Levosulpiride Preparation Products And Raw materials

Raw materials

Lithium tert-butoxide Ethanol Aminosulfonate Sulpiride (S)-2-(Aminomethyl)-1-ethylpyrrolidine
2-(Aminomethyl)-1-ethylpyrrolidine L-Proline Lithium Aluminum Hydride Sodium hydroxide L(+)-Tartaric acid
Methyl benzoate

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Preparation Products

Levosulpiride Suppliers

Global( 423)Suppliers
Supplier Tel Email Country ProdList Advantage
Hong Kong Excellence Biotechnology Co., Ltd. 		+86-86-18838029171 +8618126314766 ada@sh-teruiop.com China 893 58
Sigma Audley 		+86-18336680971 +86-18126314766 nova@sh-teruiop.com China 525 58
Shanghai Aosiris new Material Technology Co., LTD 		86-15139564871 +8615139564871 wrjmoon2000@163.com China 354 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Xi'an Kono chem co., Ltd., 		029-86107037 13289246953 info@konochemical.com China 2995 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 47465 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
SIMAGCHEM CORP 		+86-13806087780 sale@simagchem.com China 17367 58
Supplier Advantage
Hong Kong Excellence Biotechnology Co., Ltd. 		58
Sigma Audley 		58
Shanghai Aosiris new Material Technology Co., LTD 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Xi'an Kono chem co., Ltd., 		58
Hubei xin bonus chemical co. LTD 		58
Chongqing Chemdad Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
SIMAGCHEM CORP 		58

View Lastest Price from Levosulpiride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Levosulpiride pictures 2024-04-23 Levosulpiride
23672-07-3
 US $100.00 / kg 1kg 99.9% 20tons Hong Kong Excellence Biotechnology Co., Ltd.
Levosulpiride pictures 2024-04-17 Levosulpiride
23672-07-3
 US $3.00-1.00 / kg 1kg 99.9% 10 tons Shanghai Aosiris new Material Technology Co., LTD
Levosulpiride pictures 2024-03-16 Levosulpiride
23672-07-3
 US $35.00-25.00 / kg 1kg 99.8% 200tons/year Sigma Audley
  • Levosulpiride pictures
  • Levosulpiride
    23672-07-3
  • US $100.00 / kg
  • 99.9%
  • Hong Kong Excellence Biotechnology Co., Ltd.
  • Levosulpiride pictures
  • Levosulpiride
    23672-07-3
  • US $3.00-1.00 / kg
  • 99.9%
  • Shanghai Aosiris new Material Technology Co., LTD

Levosulpiride Spectrum

Levosulpiride(23672-07-3)1HNMRLevosulpiride(23672-07-3)IR

23672-07-3(Levosulpiride)Related Search:

METSULFURON METHYL Bensulfuron methyl Amisulpride Thiophanate-methyl Methyl acetate
Chlorantraniliprole Methyl acrylate Benzamide Kresoxim-methyl Methylparaben
Calcium levofolinate Levomilnacipran Levothyroxine sodium L(+)-Tartaric acid Methyl
L(-)-Carvone Levodopa L(-)-Carnitine hydrochloride

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(s)-(-)-n-((1-ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide (s)-(-)-o-anisamid Levosulpiride, (S)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide S-(-)-Sulpiride，Levobren，Levopraid (s)-(-)-n-((1-ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide 5-(aminosulfonyl)-n-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-benzamid ( s-(-)-benzamid rv-12309 s-(-)-n-(1-ethyl-2-pyrrolidinomethyl)-2-methoxy-5-sulfamoylebenzamide s-(-)-sulpiride (S)--5-Aminosulfonyl-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxybenzamide levosupride (S)-(-)-5-(Aminoulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide Levopride 5-(AMinosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]Methyl]-2-Methoxy-benzaMide 5-(AMinosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]Methyl]-2-benzaMide l-Sulpirid (S)-N-[(1-Ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide Levosulpiride (S)-(-)-5-(aMinosulfonyl)-N-[(1-ethyl-2-pyrrolinyl)Methyl] Levosulpiride (Irritable Bowel SyndroMe) (S)-(-)-Sulpir (S)-(-)-SULPIRIDE (S)-(-)-5-AMINOSULFONYL-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-METHOXYBENZAMIDE 5-(aminosulfonyl)-n-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-benzamid( levopraid rv-12309 s-(-)-n-(1-ethyl-2-pyrrolidinomethyl)-2-methoxy-5-sulfamoylebenzamide (-)-5-AMINOSULFONYL-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-METHOXY-BENZAMIDE (S)-(-)-Sulpiride, Vetranal S(-)-SULPIRIDE DOPAMINE D1 ANTAGONIS LEVOSULPIRIDE/LEVOSULPRIDE Benzamide, 5-(aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy-, (S)- Benzamide, 5-(aminosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-methoxy- (9CI) l-Sulpiride (S)-5-AMINOSULFONYL-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-METHOXYBENZAMIDE (-)-N-1-[ETHYLPYRROLIDIN-2-YLMETHYL]-2-METHOXY-5-SULFAMOYLBENZAMIDE LEVOSULPIRIDE l-Form (S)-N-[(1-Ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide China (S)-(-)-Sulpiride (S)-(-)-Sulpiride, 98%, a selective antagonist for D2 dopamine receptor LEVOSULPIRIDE (RV-12309) Left-handed sulpiride (S)-(-)-Sulpiride> Benzamide, 5-(aminosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-methoxy- Levosulpiride USP/EP/BP L-Sulpiride Impurity LevosulpirideQ: What is Levosulpiride Q: What is the CAS Number of Levosulpiride Q: What is the storage condition of Levosulpiride Q: What are the applications of Levosulpiride LevosulprideQ: What is Levosulpride Q: What is the CAS Number of Levosulpride Levosulpride Lform of Sulpiride Levosulpiride (S)-(-)-Sulpiride Caprylic Acid Impurity 36 LEVOSULPRIDE 60% SR PELLETS 23672-07-3 C15H23N3O4O4 Analytical Standards Analytical Chromatography Product Catalog Alphabetic SN - SZ Dopamine receptor API