Chinese Japanese Germany


Description References
Chemical Name:
Zefei;Gemcel;GemLip;LY-18011;Folfugem;NSC 613327;GeMcitabin;Gamcitabine;GeMictabine;GEMCITABINE
Molecular Formula:
Formula Weight:
MOL File:

Gemcitabine Properties

Melting point:
168,64 C
365 +425.36°; D +71.51°
CAS DataBase Reference
95058-81-4(CAS DataBase Reference)


Hazard Codes  Xn,Xi
Risk Statements  21-36/38-46-62-63
Safety Statements  25-26-36/37-53
Hazardous Substances Data 95058-81-4(Hazardous Substances Data)
Toxicity LD10 i.v. in rats: 200 mg/m2 (Abbruzzese)

Gemcitabine price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 11690 Gemcitabine ≥98% 95058-81-4 10mg $40 2017-11-08 Buy
Cayman Chemical 11690 Gemcitabine ≥98% 95058-81-4 25mg $71 2017-11-08 Buy
Cayman Chemical 11690 Gemcitabine ≥98% 95058-81-4 50mg $135 2017-11-08 Buy
Cayman Chemical 11690 Gemcitabine ≥98% 95058-81-4 100mg $240 2017-11-08 Buy

Gemcitabine Chemical Properties,Uses,Production


Gemcitabine (2’,2’-difluorodeoxycytidine; dFdCyd) is a novel deoxycytidine analogue with both structural and metabolic similarities to cytarabine. It has a broad spectrum of antitumor activity in preclinical murine leukemia and solid tumor models. This drug requires intracellular phosphorylation that results in the accumulation of difluorodeoxycytidine triphosphate (dFdCTP). The dFdCTP competes with deoxycytidine triphosphate (dCTP) for incorporation into DNA, which in turn inhibits DNA synthesis and terminates DNA chain elongation. In addition, this drug reduces intracellular deoxynucleoside triphosphate pools, presumably through the inhibition of ribonucleotide reductase.
Gemcitabine is used alone or with other treatments/medications to treat certain types of cancer (including breast cancer, non-small cell lung cancer, ovarian cancer, pancreatic cancer, bladder cancer, bone cancer, Ewing’s sarcoma, mesenchymal chondrosarcoma osteosarcoma, dedifferentiated chondrosarcoma, head and neck cancers-cancer of the nasopharynx, hepatobiliary cancers including gallbladder cancer, Hodgkin lymphoma, kidney cancer, malignant pleural mesothelioma, non Hodgkin lymphoma, non-melanoma skin cancer – dermatofibrosarcoma protuberans (DFSP), occult primary, small cell lung cancer, soft tissue sarcoma, testicular cancer, thymic malignancies, uterine malignancies). It is a chemotherapy drug that works by slowing or stopping the growth of cancer cells. One commercial product of gemcitabine is Gemzar, which is supplied in a sterile form for intravenous use only.


[1] H. A. Burris, M. J. Moore, J. Andersen, M. R. Green, M. L. Rothenberg, M. R. Modiano, M. C. Cripps, R. K. Portenoy, A. M. Storniolo, P. Tarassoff, R. Nelson, F. A. Dorr, C. D. Stephens, D. D. Von Hoff (1997) Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial, 15, 2403-2413


Gemcitabine(Gemzar) belongs to the group of medicines called antimetabolites. It is used alone or in combination with other medicines to treat cancer of the breast, ovary, pancreas, and lung. Gemcitabine interferes with the growth of cancer cells, which a

Gemcitabine Preparation Products And Raw materials

Raw materials

Preparation Products

Gemcitabine Suppliers

Global( 295)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Lianyungang happen teng technology co., LTD
15950718863 CHINA 304 58
Frapp's ChemicalNFTZ Co., Ltd.
+86 (576) 8169-6106
+86 (576) 8169-6105 China 887 50
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 China 19954 60
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 CHINA 3218 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 22144 58
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497 CHINA 1529 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20803 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 CHINA 1374 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32765 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070; CHINA 3015 60

95058-81-4(Gemcitabine)Related Search:

  • 2'-Deoxy-2',2'-difluro cytidine Hydrochloride
  • C9H11F2N3O4
  • 2'-Deoxy-2',2'-difluoro-D-cytidine
  • 2',2'-Difluorodeoxycytidine
  • Cytidine, 2'-deoxy-2',2'-difluoro-
  • gemicitabine
  • NSC 613327
  • gencitabine base
  • 2',2'-Difluorodeoxycytidine (Gemcitabine base)
  • API
  • LY-18011
  • 3-Deoxy-2,2-difluoro-D-ribofuranose-3,5-dibenzoate
  • Gecitabine base
  • Antineoplastic drug, difluorine nucleoside analog
  • Folfugem
  • Gamcitabine
  • Gemcel
  • GemLip
  • Zefei
  • 4-amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one (Gemcitabine base)
  • GeMcitabine T8
  • GeMcitabine API
  • 122111-11-9 D-erythro-pentofuranose
  • GeMictabine
  • dFdC, dFdCyd, LY-188011
  • Antineoplastic
  • GeMcitabin
  • 2'-Deoxy-2',2'-difluorocytidine, >=99%
  • Inhibitors
  • Gemcitabine free base
  • 1-(4-Amino-2-oxo-1H-pyrimidin-1-yl)-2-deoxy-2,2-difluoro-beta-D-ribofuranose
  • 2'-Deoxy-2',2'-difluro cytidine
  • 4-amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
  • 95058-81-4
Copyright 2017 © ChemicalBook. All rights reserved