2-Amino-6-fluoropyridine
- CAS No.
- 1597-32-6
- Chemical Name:
- 2-Amino-6-fluoropyridine
- Synonyms
- 6-Fluoropyridin-2-amine;6-FLUORO-PYRIDIN-2-YLAMINE;EOS-60628;6-Fluoro-2-pyridinamine;2-Fluoro-6-aminopyridine;2-AMINO-6-FLUOROPYRIDINE;2-Pyridinamine, 6-fluoro-;2-AMino-6-fluoropyriMidine;2-Amino-6-fluoropyridine >2-Amino-6-fluoropyridine 98%
- CBNumber:
- CB4438746
- Molecular Formula:
- C5H5FN2
- Molecular Weight:
- 112.11
- MDL Number:
- MFCD04114200
- MOL File:
- 1597-32-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-Amino-6-fluoropyridine 98% | 725064 | 1g | $46.8 |
| 2-Amino-6-fluoropyridine 98% | 725064 | 5g | $173 |
| 2-Amino-6-fluoropyridine >98.0%(GC)(T) | A2879 | 1g | $37 |
| 2-Amino-6-fluoropyridine >98.0%(GC)(T) | A2879 | 5g | $118 |
| 6-Fluoropyridin-2-amine | F596293 | 500mg | $65 |
| More product size | |||
| Melting point | 59-61°C |
|---|---|
| Boiling point | 225.0±20.0 °C(Predicted) |
| Density | 1.257±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 2.26±0.24(Predicted) |
| color | White to Almost white |
| InChI | InChI=1S/C5H5FN2/c6-4-2-1-3-5(7)8-4/h1-3H,(H2,7,8) |
| InChIKey | UZALKVXCOUSWSL-UHFFFAOYSA-N |
| SMILES | C1(N)=NC(F)=CC=C1 |
| CAS DataBase Reference | 1597-32-6(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H318-H335 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1 | |||||||||
| HS Code | 2933399990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2-Amino-6-fluoropyridine price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 725064 | 2-Amino-6-fluoropyridine 98% | 1597-32-6 | 1g | $46.8 | 2023-06-20 | Buy |
| Sigma-Aldrich | 725064 | 2-Amino-6-fluoropyridine 98% | 1597-32-6 | 5g | $173 | 2023-06-20 | Buy |
| TCI Chemical | A2879 | 2-Amino-6-fluoropyridine >98.0%(GC)(T) | 1597-32-6 | 1g | $37 | 2026-04-30 | Buy |
| TCI Chemical | A2879 | 2-Amino-6-fluoropyridine >98.0%(GC)(T) | 1597-32-6 | 5g | $118 | 2026-04-30 | Buy |
| TRC | F596293 | 6-Fluoropyridin-2-amine | 1597-32-6 | 500mg | $65 | 2021-12-16 | Buy |
2-Amino-6-fluoropyridine Chemical Properties,Uses,Production
Description
2-Amino-6-fluoropyridine is an organic intermediate that can be prepared via the nucleophilic substitution reaction of 2,6-difluoropyridine with ammonia.
Uses
2-Amino-6-fluoropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Synthesis
1513-65-1
1597-32-6
The general procedure for the synthesis of 2-amino-6-fluoropyridine from 2,6-difluoropyridine was as follows: 2,6-difluoropyridine (50 g, 434 mmol) was dissolved in ammonium hydroxide solution (200 mL, 28.0-30.0%) in a steel tube and the reaction was heated for 15 hr at 105 °C. Upon completion of the reaction, the mixture was cooled in an ice bath and the precipitate was subsequently collected by filtration. The precipitate was washed with cold water and dried to give 6-fluoro-2-pyridinamine (45.8 g, 94% yield) as a white solid. The structure of the product was confirmed by 1H-NMR (CDCl3): δ 7.53 (m, 1H), 6.36 (dd, 1H), 6.26 (dd, 1H), 4.56 (s, 2H).
References
[1] Patent: WO2006/76131, 2006, A2. Location in patent: Page/Page column 39-40
[2] Patent: WO2007/27999, 2007, A2. Location in patent: Page/Page column 35
[3] Patent: WO2006/36816, 2006, A2. Location in patent: Page/Page column 59-60
[4] Patent: WO2006/26703, 2006, A2. Location in patent: Page/Page column 64-65
[5] Patent: WO2007/87549, 2007, A2. Location in patent: Page/Page column 44; 59
2-Amino-6-fluoropyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Dongfan Chem. Co., Ltd. | 021-34500607 13391355195 | sales@dfanchem.com | CHINA | 61 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| Chembon Pharmaceutical Co., Ltd. | +86-28-8425-2981 | CHINA | 722 | 55 | |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10404 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
View Lastest Price from 2-Amino-6-fluoropyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-25 | 2-Amino-6-fluoropyridine
1597-32-6
|
US $1.10 / g | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-01-10 | 2-Amino-6-fluoropyridine
1597-32-6
|
US $7.00 / KG | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 2-Amino-6-fluoropyridine
1597-32-6
- US $1.10 / g
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
-
- 2-Amino-6-fluoropyridine
1597-32-6
- US $7.00 / KG
- 99%
- Career Henan Chemical Co
