ANTI-GLUTAMINE SYNTHETASE
- CAS No.
- Chemical Name:
- ANTI-GLUTAMINE SYNTHETASE
- Synonyms
- glul;Anti-GS;Anti-FPC;Anti-GLNS;Anti-BTPS2;Anti-DP2.5;ANTI-GLUTAMINE SYNTHETASE;Anti-adenomatosis polyposis coli;ANTI-GLUTAMINE SYNTHETASE, SHEEP;Anti-GS antibody produced in rabbit
- CBNumber:
- CB4448673
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01322097
- MOL File:
- Mol file
ANTI-GLUTAMINE SYNTHETASE price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | WH0002752M1 | Monoclonal Anti-GLUL antibody produced in mouse clone 2B12, purified immunoglobulin, buffered aqueous solution | 50μg | $524 | 2024-03-01 | Buy | |
| Sigma-Aldrich | WH0000324M1 | Monoclonal Anti-APC antibody produced in mouse clone 3E2, purified immunoglobulin, buffered aqueous solution | 100μg | $524 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB5700213 | Anti-GLUL antibody produced in rabbit | 100μL | $405 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA007316 | Anti-GLUL antibody produced in rabbit Ab1, Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 25μL | $294 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA007571 | Anti-GLUL antibody produced in rabbit Ab2, Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $547 | 2024-03-01 | Buy |
ANTI-GLUTAMINE SYNTHETASE Chemical Properties,Uses,Production
Uses
Anti-Glutamine Synthetase antibody has been used for the detection and localization of GS by immunoblotting and immunohistochemistry.
General Description
Anti-Glutamine Synthetase is produced in rabbit using a synthetic peptide corresponding to the C-terminus of mouse glutamine synthetase (GS) conjugated to keyhole limpet hemocyanin (KLH) as immunogen. This sequence is identical in human, bovine, rat, hamster and pig GS, and highly conserved in chicken GS. GS is found in mammals as an octamer of identical 45 kDa subunits. It is localized in glial cells of various species. It is present in the brain primarily in astrocytes and in the retina in Muller glial cells that support neurons using glutamate as a neurotransmitter. GS is found in several brain regions including hippocampus, cerebral cortex, neostriatum and cerebellar granular layer, corresponding to sites with high glutamate receptor density.
Biochem/physiol Actions
GLUL (glutamate-ammonia ligase) gene encodes an ATP-dependent enzyme that catalyzes the synthesis of glutamine from glutamate and ammonia (nitrogen source). It is a member of the glutamine synthetase family. It is an essential enzyme in glutamine neogenesis. It functions in detoxification of ammonia and glutamate, acid-base homeostasis, cell signaling, and cell proliferation. It has a role in proliferation of fetal skin fibroblasts. Defects in this gene are associated with congenital glutamine deficiency. Overexpression of this gene has been observed in some primary liver cancer samples.
ANTI-GLUTAMINE SYNTHETASE Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-GLUTAMINE SYNTHETASE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 15926423062 | 422450190@qq.com | China | 10132 | 58 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 58 |