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1,4-Butanediol

1,4-Butanediol
1,4-Butanediol structure
CAS No.
110-63-4
Chemical Name:
1,4-Butanediol
Synonyms
BDO;sucolb;1,4-BD;diol14b;Sucol B;Diol 14B;Dabco BDO;Butanediol;agrisynthb1d;4-Butanediol
CBNumber:
CB4452184
Molecular Formula:
C4H10O2
Formula Weight:
90.12
MOL File:
110-63-4.mol

1,4-Butanediol Properties

Melting point:
20 °C
Boiling point:
230 °C(lit.)
Density 
1.017 g/mL at 25 °C(lit.)
vapor density 
3.1 (vs air)
vapor pressure 
<0.1 hPa (20 °C)
refractive index 
n20/D 1.445(lit.)
Flash point:
135 °C
storage temp. 
2-8°C
PH
7-8 (500g/l, H2O, 20℃)
explosive limit
1.95-18.3%(V)
Water Solubility 
Miscible
Sensitive 
Hygroscopic
BRN 
1633445
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents, mineral acids, acid chlorides, acid anhydrides.
InChIKey
WERYXYBDKMZEQL-UHFFFAOYSA-N
CAS DataBase Reference
110-63-4(CAS DataBase Reference)
NIST Chemistry Reference
1,4-Butanediol(110-63-4)
EPA Substance Registry System
1,4-Butanediol(110-63-4)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H336-H302
Precautionary statements  P264-P270-P301+P312a-P330-P501a-P261-P301+P312+P330
Hazard Codes  Xn
Risk Statements  22-67
Safety Statements  36-23-24/25
WGK Germany  1
RTECS  EK0525000
Autoignition Temperature 698 °F
TSCA  Yes
HS Code  29053980
Toxicity LD50 orally in Rabbit: 1525 mg/kg LD50 dermal Rabbit > 2000 mg/kg

NFPA 704

Diamond Hazard Value Description
1
0
Health  
Flammability   1 Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia)
Instability   0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
Special  

(NFPA, 2010)

1,4-Butanediol price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 240559 1,4-Butanediol ≥99% 110-63-4 2g $24.9 2018-11-20 Buy
Sigma-Aldrich 240559 1,4-Butanediol ≥99% 110-63-4 100g $74 2018-11-20 Buy
Alfa Aesar L03491 1,4-Butanediol, 99% 110-63-4 1000g $32.1 2018-11-15 Buy
Alfa Aesar L03491 1,4-Butanediol, 99% 110-63-4 250g $21.2 2018-11-15 Buy
Sigma-Aldrich 493732 1,4-Butanediol 99% 110-63-4 1l $32.1 2018-11-20 Buy

1,4-Butanediol Chemical Properties,Uses,Production

Chemical Properties

1,4-butanediol (1,4-BD) is a colorless, viscous liquid derived from butane by placement of alcohol groups at each end of its molecular chain and is one of four stable isomers of butanediol.the hydroxyl function of each end group of the Butanediol reacts with different mono- and bifunctional reagents: for example with dicarboxylic acids to polyesters, with diisocyanates to polyurethanes, or with phosgene to polycarbonates. 1.4-Butanediol (BDO) is a high-quality intermediate. BDO and its derivatives are widely used for producing plastics, solvents, electronic chemicals and elastic fibers. Additionally BDO is also a building block for the synthesis of polyesterpolyols and polyetherpolyols. BASF is the most significant producer of 1,4-Butanediol and its derivatives worldwide.

Uses

  1. Butanediol and its derivatives is used in a broad spectrum of applications in the chemical industry; amongst others in the manufacturing of technical plastics, polyurethanes, solvents, electronic chemicals and elastic fibres.
  2. 1,4-Butanediol is used in the synthesis of epothilones, a new class of cancer drugs. Also used in the stereoselective synthesis of (-)-Brevisamide.
  3. 1,4-Butanediol's largest use is within tetrahydrofuran (THF) production, used to make polytetramethylene ether glycol, which goes mainly into spandex fibers, urethane elastomers, and copolyester ethers.
  4. It is commonly used as a solvent in the chemical industry to manufacture gamma-butyrolactone and elastic fibers like spandex.
  5. It is used as a cross-linking agent for thermoplastic urethanes, polyester plasticizers, paints and coatings.
  6. It undergoes dehydration in the presence of phosphoric acid yielded teterahydrofuran, which is an important solvent used for various applications.
  7. It acts an intermediate and is used to manufacture polytetramethylene ether glycol (PTMEG), polybutylene terephthalate (PBT) and polyurethane (PU).
  8. It finds application as an industrial cleaner and a glue remover.
  9. 1,4-butanediol is also used as a plasticiser (e.g. in polyesters and cellulosics), as a carrier solvent in printing ink, a cleaning agent, an adhesive (in leather, plastics, polyester laminates and polyurethane footwear), in agricultural and veterinary chemicals and in coatings (in paints, varnishes and films).

Uses

butylene glycol is a solvent with good antimicrobial action. It enhances the preservative activity of parabens. Butylene glycol also serves as a humectant and viscosity controller, and to mask odor.

Uses

1,4-Butanediol is used to produce polybutyleneterephthalate, a thermoplastic polyester;and in making tetrahydrofuran, butyrolactones,and polymeric plasticizers.

Production Methods

Methods of manufacturing:
The most prevalent 1,4-BD production route worldwide is BASF's Reppe process, which reacts acetylene and formaldehyde. Acetylene reacts with two equivalents of formaldehyde to form 1,4-butynediol, also known as but-2-yne- 1,4-diol. Hydrogenation of 1,4-butynediol gives 1,4-butanediol. 1,4-BD is also made on a large industrial scale by continuous hydrogenation of the 2-butyne- 1,4-diol over modified nickel catalysts. The one-stage flow process is carried out at 80 - 160 deg C and 300 bar.
Mitsubishi uses a three-step process:
(1) the catalytic reaction of butadiene and acetic acid yields 1,4-diacetoxy-2-butene;
(2) subsequent hydrogenation gives 1,4-diacetoxybutane; and
(3) hydrolysis leads to 1,4-butanediol.

General Description

Odorless colorless liquid or solid (depending upon temperature).

Air & Water Reactions

Highly flammable. 1,4-Butanediol is hygroscopic. Water soluble.

Reactivity Profile

1,4-Butanediol is heat and light sensitive. 1,4-Butanediol reacts with acid chlorides, acid anhydrides and chloroformates; reacts with oxidizing agents and reducing agents. 1,4-Butanediol is incompatible with isocyanates and acids; also incompatible with peroxides, perchloric acid, sulfuric acid, hypochlorous acid, nitric acid, caustics, acetaldehyde, nitrogen peroxide and chlorine.

Hazard

Toxic by ingestion.

Health Hazard

The acute toxic effects are mild. 1,4-Butanediolis less toxic than its unsaturate analogs,butenediol and the butynediol. The oralLD50 value in white rats and guinea pigsis ~2 mL/kg. The toxic symptoms fromingestion may include excitement, depressionof the central nervous system, nausea, anddrowsiness.

Health Hazard

Ingestion of large amounts needed to produce any symptoms.

Fire Hazard

Nonflammable liquid, flash point (open cup) 121°C.

Safety Profile

A human poison by an unspecified route. Moderately toxic byingestion and intraperitoneal routes. Human systemic effects: altered sleep time. Combustible when exposed to heat or flame. To fight fire, use alcohol foam, mist, foam, CO2, dry chemical. Incompatible with oxidizing materials. When heated to decomposition it emits acrid smoke and fumes.

Purification Methods

Distil the glycol and store it over Linde type 4A molecular sieves, or crystallise it twice from anhydrous diethyl ether/acetone, and redistil it. It has been recrystallised from the melt and doubly distilled in vacuo in the presence of Na2SO4. [Beilstein 1 IV 2515.]

1,4-Butanediol Preparation Products And Raw materials

Raw materials

Preparation Products


1,4-Butanediol Suppliers

Global( 327)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1861 55
Hebei Guanlang Biotechnology Co., Ltd.
+8619930501651
breeduan@crovellbio.com CHINA 2314 58
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
+86-571-56059825 fandachem@gmail.com CHINA 2884 55
Tianjin Zhongxin Chemtech Co., Ltd.
022-89880739
022-66880086 sales@tjzxchem.com CHINA 575 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30001 58
Hebei Ruishun Trade Co.,LTD
17052563120
Mike@rsbiology.com CHINA 302 58

View Lastest Price from 1,4-Butanediol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-10-11 1,4-Butanediol +8619930501651
110-63-4
US $2.00 / KG 1KG 99.9% 10 mt Hebei Guanlang Biotechnology Co., Ltd.
2019-04-14 1,4-Butanediol
110-63-4
US $1.00-1.00 / g 10Kg/Bag 99% 80000 Kilogram/Kilograms per Month Cangzhou Wanyou New Material Technology Co.,Ltd
2018-12-16 1,4-Butanediol
110-63-4
US $7.00 / kg 1kg 99% 100kg career henan chemical co

1,4-Butanediol Spectrum


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