Doxifluridine | 3094-09-5

Doxifluridine Properties

Melting point	188-192 °C(lit.)
alpha	D25 +18.4° (c = 0.419 in water)
Density	1.3751 (estimate)
refractive index	20 ° (C=1, H2O)
storage temp.	Inert atmosphere,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	7.4(at 25℃)
color	White
Merck	14,3437
CAS DataBase Reference	3094-09-5(CAS DataBase Reference)
FDA UNII	V1JK16Y2JP
NCI Drug Dictionary	doxifluridine

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H317

Precautionary statements

P261-P272-P280-P302+P352+P333+P313+P363-P501

Hazard Codes

Xi

Risk Statements

36/37/38

Safety Statements

26-36-24/25

WGK Germany

2

RTECS

YU7526000

Hazard Note

Irritant

HazardClass

IRRITANT, IRRITANT-HARMFUL

HS Code

29349990

Toxicity

LD50 (14 day) in mice or rats (mg/kg): >1000 i.v.: >2000 s.c.; in male, female mice, male, female rats (mg/kg): >5000, >5000, 3471, 3390 orally (Shimizu)

NFPA 704

	0
1		0

Doxifluridine price More Price(60)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	F8791	5-Fluoro-5′-deoxyuridine	3094-09-5	25MG	$86.6	2023-06-20	Buy
Sigma-Aldrich	Y0001644	Capecitabine impurity B European Pharmacopoeia (EP) Reference Standard	3094-09-5	Y0001644	$218	2023-06-20	Buy
Sigma-Aldrich	F8791	5-Fluoro-5′-deoxyuridine	3094-09-5	100MG	$267	2023-06-20	Buy
Sigma-Aldrich	F8791	5-Fluoro-5′-deoxyuridine	3094-09-5	250MG	$466	2023-06-20	Buy
Sigma-Aldrich	PHR2850	5′-deoxy-5-fluorouridine certified reference material, pharmaceutical secondary standard	3094-09-5	50MG	$452	2022-05-15	Buy

Product number	Packaging	Price	Buy
F8791	25MG	$86.6	Buy
Y0001644	Y0001644	$218	Buy
F8791	100MG	$267	Buy
F8791	250MG	$466	Buy
PHR2850	50MG	$452	Buy

Doxifluridine Chemical Properties,Uses,Production

Description

Doxifluridine is a prodrug derivative of 5-fluorouracil (5-FU). As an antineoplastic it is more potent than 5-FU in the treatment of breast, stomach, colon and rectal cancers.

Chemical Properties

White Solid

Originator

Hoffmann-LaRoche (USA)

Uses

antineoplastic, pyrimidine antimetabolite

Uses

A prodrug of 5-Flurouridine. A fluorinated pyrimidine nucleoside with cytostatic activity

Uses

An antitumor agent efficient in tumors, cell lines or in fibroblasts tranformed by H-ras or trk oncogenes. A metabolite of Capecitabine

Uses

5’-Deoxy-5-fluorouridine is a metabolite of the chemotherapeutic agent Capecitabine (C175650). 5’-Deoxy-5-fluorouridine is an antitumor agent efficient in tumors, cell lines or in fibroblasts tranformed by H-ras or trk oncogenes.

Definition

ChEBI: A pyrimidine 5'-deoxyribonucleoside that is 5-fluorouridine in which the hydroxy group at the 5' position is replaced by a hydrogen. It is an oral prodrug of the antineoplastic agent 5-fluorouracil. Designed to circumvent the rapid degradation of 5-fluoro racil by dihydropyrimidine dehydrogenase in the gut wall, it is converted into 5-fluorouracil in the presence of pyrimidine nucleoside phosphorylase.

brand name

Furtulon

Biochem/physiol Actions

Doxifluridine is an antitumor agent efficient in tumors, cell lines or in fibroblasts transformed by H-ras or trk oncogenes. Possesses anticachectic activity which is independent of its antiproliferative activity.

Doxifluridine Preparation Products And Raw materials

Raw materials

Palladium carbon fine chemical catalyzer p-Toluenesulfonic acid monohydrate Ethyl acetate Triphenylantimony Iodomethane

2,2-Dimethoxypropane

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Preparation Products

Doxifluridine Suppliers

Global( 344)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9353	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Shanghai Arbor Chemical Co., Ltd.	021-60451682	act@arborchemical.com	CHINA	906	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
career henan chemical co	58
Shanghai Arbor Chemical Co., Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58
Accela ChemBio Inc.	58
Hubei xin bonus chemical co. LTD	58
Standardpharm Co. Ltd.	58
Chongqing Chemdad Co., Ltd	58

View Lastest Price from Doxifluridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2022-05-14	Doxifluridine 3094-09-5	US $1.10 / g	1g	99.9% Min	100 Tons	Dideu Industries Group Limited
2022-02-25	Doxifluridine 3094-09-5	US $19.00 / KG	1KG	99%	100tons	Hong Kong Tiansheng New Material Trading Co., Ltd
2021-09-29	5-Fluoro-5′-deoxyuridine 3094-09-5	US $0.00 / g	1g	≥98.0%	10kg/month	WUHAN FORTUNA CHEMICAL CO., LTD

Doxifluridine
3094-09-5
US $1.10 / g
99.9% Min
Dideu Industries Group Limited

Doxifluridine
3094-09-5
US $19.00 / KG
99%
Hong Kong Tiansheng New Material Trading Co., Ltd

5-Fluoro-5′-deoxyuridine
3094-09-5
US $0.00 / g
≥98.0%
WUHAN FORTUNA CHEMICAL CO., LTD

Doxifluridine Spectrum

Doxifluridine(3094-09-5)¹HNMR

3094-09-5(Doxifluridine)Related Search:

5-Fluorouridine Chenodeoxycholic acid 1-beta-D-Arabinofuranosyluracil Ursodeoxycholic acid 5-Fluorouracil

DL-PHENYLEPHRINE HYDROCHLORIDE Trifluridine Floxuridine 3'-O-(5'-Deoxy-α-D-ribofuranosyl) Capecitabine 5'-Deoxy-5-fluorocytidine

2'-O-(5'-Deoxy-β-D-ribofuranosyl) Capecitabine 5'-deoxy-5-fluore-N-[(pentoyloxy)carbonyl]cytidine 2',3'-diacetate CAPECITABINE related substance USP 5'-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine alpha-Capecitabine

2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine 5'-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine uridine diphosphate glucose {= UDP-glucose}

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1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyl-oxolan-2-yl]-5-fluoro-pyrimidine-2,4-dione 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoropyrimidine-2,4-dione 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyl-tetrahydrofuran-2-yl]-5-fluoro-pyrimidine-2,4-quinone Capecitabine Related Compound B (20 mg) (5'-deoxy-5-fluorouridine) 5μdFUrd, Doxifluridine 5μdFUrd, 5-Fluoro-5μ-deoxyuridine 5’-Deoxy-5-fluomuridine 2,4(1H,3H)-Pyrimidinedione, 1-(5-deoxy-b-D-ribofuranosyl)-5-fluoro- 5Urd, 5-Fluoro-5deoxyuridine URIDINE,5''-DEOXY-5-FLUORO 1-[(2s,3s,4r,5s)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl]-5-fluoropyrimidine-2,4(1h,3h)-dione flutron furtulon Doxifluridine 3094-9-5 1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil 5’dUrd, 5-Fluoro-5’-deoxyuridine, 5’-DFUR, Doxifluridine 5'-dFUrd Doxifluridine 1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil Doxifluridine(Ro 21-9738) CAPECITABINE related substance USP B RO-21-9738 (+)-5-FLUORO-5'-DEOXYURIDINE 5-FLUORO-5'-DEOXYURIDINE 5'-DEOXY-5-FLUOROURIDINE 5'-DEOXYFLUOROURIDINE 5'-DFUR 5'DFURD DOXIFLURIDINE MURINE RECOMBINANT Doxifluridine (furtulon) DOXIFLUIRDINE 5'-Deoxy-fluorouridine(DFUR)/Doxifluridine (+)-5-FLUORO-5'-DEOXYURIDINE 97% 5-FLURO-5’-DEOXYURIDINE 5Deoxy-5-fluorouridine, 5DFUR, 5dFUrd, Ro-21-9738 Doxifluidine DOXIFLURIDINE(SUBJECTTOPATENTFREE) (+)-5-Fluoro-5'-deoxyuridine98% 5-Fluorodesoxyuridine Uridine, 5'-deoxy-5-fluoro- (8CI, 9CI) 5-FLUORO-5''-DEOXYURIDINE / DOXIFLURIDINE / 5''-DEOXY-FLUOROURIDINE (+)-Doxifluridine, (+)-1-(beta-D-5'-Deoxyribofuranosyl)-5-fluorouracil 5-F-5‘-dU 5'-DFUR-13C5 (5'-Deoxy-5-fluorouridine, Doxifluridine-13C5) AMC 0101 5-cl-5'-dU Doxifluridine, >=98.5% Capecitabine USP RC B Doxifluridine Doxifluridine 5’-deoxy-5-fluoro-uridin Doxifluridine/5-Fluoro-5′-deoxyuridine Capecitabine Impurity 16（Capecitabine EP Impurity B） 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyl-2-oxolanyl]-5-fluoropyrimidine-2,4-dione Capecitabine Impurity B 5'-Deoxy-5-fluorouridine> Capecitabine EP Impurity B (5'-DFUR, Doxifluridine) 5’-deoxy-5-fluorouridine, Doxifluridine 5'-DFUR Doxifluridine USP/EP/BP Capecitabine EP Impurity B/ Capecitabine Related Compund B (Doxifluridine/ Deoxy-5-fluorouridine)