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Doxifluridine

Doxifluridine
Doxifluridine structure
CAS No.
3094-09-5
Chemical Name:
Doxifluridine
Synonyms
5'DFURD;5'-DFUR;flutron;AMC 0101;furtulon;5-F-5‘-dU;RO-21-9738;5-cl-5'-dU;Doxifluidine;DOXIFLURIDINE
CBNumber:
CB4461786
Molecular Formula:
C9H11FN2O5
Formula Weight:
246.19
MOL File:
3094-09-5.mol

Doxifluridine Properties

Melting point:
188-192 °C(lit.)
alpha 
D25 +18.4° (c = 0.419 in water)
Density 
1.3751 (estimate)
refractive index 
20 ° (C=1, H2O)
storage temp. 
-20°C Freezer
pka
7.4(at 25℃)
Merck 
14,3437
CAS DataBase Reference
3094-09-5(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P261-P272-P280-P302+P352+P333+P313+P363-P501
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-24/25
WGK Germany  2
RTECS  YU7526000
Hazard Note  Irritant
HazardClass  IRRITANT, IRRITANT-HARMFUL
HS Code  29349990
Toxicity LD50 (14 day) in mice or rats (mg/kg): >1000 i.v.: >2000 s.c.; in male, female mice, male, female rats (mg/kg): >5000, >5000, 3471, 3390 orally (Shimizu)

Doxifluridine price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D3579 5'-Deoxy-5-fluorouridine >98.0%(HPLC)(T) 3094-09-5 1g $106 2018-11-22 Buy
TCI Chemical D3579 5'-Deoxy-5-fluorouridine >98.0%(HPLC)(T) 3094-09-5 5g $320 2018-11-22 Buy
Cayman Chemical 10253 Doxifluridine ≥98% 3094-09-5 50mg $49 2018-11-13 Buy
Cayman Chemical 10253 Doxifluridine ≥98% 3094-09-5 100mg $93 2018-11-13 Buy
Cayman Chemical 10253 Doxifluridine ≥98% 3094-09-5 500mg $368 2018-11-19 Buy

Doxifluridine Chemical Properties,Uses,Production

Description

Doxifluridine is a prodrug derivative of 5-fluorouracil (5-FU). As an antineoplastic it is more potent than 5-FU in the treatment of breast, stomach, colon and rectal cancers.

Chemical Properties

White Solid

Originator

Hoffmann-LaRoche (USA)

Uses

A prodrug of 5-Flurouridine. A fluorinated pyrimidine nucleoside with cytostatic activity

Uses

An antitumor agent efficient in tumors, cell lines or in fibroblasts tranformed by H-ras or trk oncogenes. A metabolite of Capecitabine

Uses

5’-Deoxy-5-fluorouridine is a metabolite of the chemotherapeutic agent Capecitabine (C175650). 5’-Deoxy-5-fluorouridine is an antitumor agent efficient in tumors, cell lines or in fibroblasts tranformed by H-ras or trk oncogenes.

Uses

antineoplastic, pyrimidine antimetabolite

Definition

ChEBI: A pyrimidine 5'-deoxyribonucleoside that is 5-fluorouridine in which the hydroxy group at the 5' position is replaced by a hydrogen. It is an oral prodrug of the antineoplastic agent 5-fluorouracil. Designed to circumvent the rapid degradation of 5-fluoro racil by dihydropyrimidine dehydrogenase in the gut wall, it is converted into 5-fluorouracil in the presence of pyrimidine nucleoside phosphorylase.

brand name

Furtulon

Doxifluridine Preparation Products And Raw materials

Raw materials

Preparation Products


Doxifluridine Suppliers

Global( 246)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19918 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21676 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
+86-571-56059825 fandachem@gmail.com CHINA 2887 55
PI & PI BIOTECH INC.
020-81716320
020-81716319 Sales@pipitech.com CHINA 2543 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30001 58
Shanghai Arbor Chemical Co., Ltd.
021-60451682
021-60451683 act@arborchemical.com CHINA 906 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58
Accela ChemBio Inc.
(+1)-858-699-3322
(+1)-858-876-1948 info@accelachem.com United States 12231 58

View Lastest Price from Doxifluridine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-21 Doxifluridine
3094-09-5
US $7.00 / kg 1kg 99% 100kg career henan chemical co

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