ChemicalBook >> CAS DataBase List >>Abacavir

Abacavir

Abacavir structure

CAS No.: 783292-37-5

Chemical Name:: Abacavir

Synonyms: Trans -Abacavir;(Abacavir EP Impurity D);Abacavir Impurity 4(Abacavir EP Impurity D);[(1R,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-enyl]methanol;2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R,4R)-rel-;(1R,?4R)?-?rel-4-?[2-Amino-?6-?(cyclopropylamino)?-?9H-?purin-?9-?yl]?-?2-?cyclopentene-?1-?methanol

CBNumber:: CB44656074

Molecular Formula:: C14H18N6O

Molecular Weight:: 286.33

MDL Number:

MOL File:: 783292-37-5.mol

Last updated:2022-12-21 16:56:50

Request For Quotation

Abacavir Properties

Boiling point	636.0±65.0 °C(Predicted)
Density	1.70±0.1 g/cm3(Predicted)
pka	14.86±0.10(Predicted)
FDA UNII	0903H757IU

Abacavir Chemical Properties,Uses,Production

Uses

(1R,?4R)?-?rel-4-?[2-Amino-?6-?(cyclopropylamino)?-?9H-?purin-?9-?yl]?-?2-?cyclopentene-?1-?methanol (Abacavir EP Impurity D) is an impurity of Abacavir A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

Abacavir Preparation Products And Raw materials

Raw materials

Preparation Products

Abacavir Suppliers

Global( 14)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	55717	58
Guangzhou Dreampharm Biotechnology Co., Ltd.	17825480238	3008233717@qq.com	China	9844	12
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.	020-89854820	sales@jzpharma.cn	China	1072	58
Jinan blalong chemical co. LTD	2710913286@.com	1513643261@qq.com	China	14253	58
Guangzhou Juntang Technology Co., Ltd	020-36607679 13502246435	sales@dmstandards.com	China	10951	58
Foshan Treasure Biotechnology Co., Ltd	0757-85921206 18520245316	2329783215@qq.com	China	12664	58
Shenzhen Roark Pharma-Tec Co., Ltd.	13128912434	2880126944@qq.com	China	2580	58

Supplier	Advantage
Standardpharm Co. Ltd.	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	58
Guangzhou Dreampharm Biotechnology Co., Ltd.	12
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.	58
Jinan blalong chemical co. LTD	58
Guangzhou Juntang Technology Co., Ltd	58
Foshan Treasure Biotechnology Co., Ltd	58
Shenzhen Roark Pharma-Tec Co., Ltd.	58

783292-37-5(Abacavir)Related Search:

Lamivudine Abacavir Carboxylate Abacavir-d4 Abacavir Abacavir 5’-Phosphate

2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R-cis)- trans-Abacavir Hydrochloride Abacavir 2,6-Diaminopurine 6-aminocarbovir

(1R,3S)-3-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]cyclopentaneMethanol (1S–4R)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol hydrochloride Abacavir Related CoMpound D Abacavir 2-Amino-6-cyclopropylamino-9H-purine

Abacavir sulfate

1of4

Abacavir Impurity 4(Abacavir EP Impurity D) (Abacavir EP Impurity D) (1R,?4R)?-?rel-4-?[2-Amino-?6-?(cyclopropylamino)?-?9H-?purin-?9-?yl]?-?2-?cyclopentene-?1-?methanol [(1R,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-enyl]methanol 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R,4R)-rel- Trans -Abacavir 783292-37-5