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4-THIOURACIL

4-THIOURACIL structure

CAS No.: 591-28-6

Chemical Name:: 4-THIOURACIL

Synonyms: KC 135;4-thiouracyl;4-THIOURACIL;4-Thiouracil97%;Uracil, 4-thio-;4-Thiouracil 97%;4-Thiouracil ,98%;4-mercaptopyrimidin-2-ol;4-Thioxo-1H-pyrimidin-2-one;2-HYDROXY-4-MERCAPTOPYRIMIDINE

CBNumber:: CB4469328

Molecular Formula:: C4H4N2OS

Molecular Weight:: 128.15

MDL Number:: MFCD00090842

MOL File:: 591-28-6.mol

MSDS File:: SDS

Last updated:2023-05-21 10:59:17

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4-THIOURACIL Properties

Melting point	295 °C (dec.) (lit.)
Density	1.368 (estimate)
refractive index	1.7000 (estimate)
storage temp.	Store at -20°C
solubility	1 M NaOH: soluble50mg/mL
form	Powder
pka	5.38±0.20(Predicted)
color	Yellow
CAS DataBase Reference	591-28-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302+H312+H332

Precautionary statements

P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312

Hazard Codes

Risk Statements

20/21/22

Safety Statements

WGK Germany

HS Code

29335990

NFPA 704

	1
2		0

4-THIOURACIL price More Price(15)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	440736	4-Thiouracil 97%	591-28-6	1g	$105	2024-03-01	Buy
TCI Chemical	T2757	4-Thiouracil >97.0%(HPLC)(T)	591-28-6	1g	$137	2024-03-01	Buy
Alfa Aesar	H61919	4-Thiouracil, 97%	591-28-6	1g	$80.65	2024-03-01	Buy
Alfa Aesar	H61919	4-Thiouracil, 97%	591-28-6	250mg	$29.1	2023-06-20	Buy
Cayman Chemical	16952	4-Thiouracil ≥98%	591-28-6	1g	$88	2024-03-01	Buy

Product number	Packaging	Price	Buy
440736	1g	$105	Buy
T2757	1g	$137	Buy
H61919	1g	$80.65	Buy
H61919	250mg	$29.1	Buy
16952	1g	$88	Buy

4-THIOURACIL Chemical Properties,Uses,Production

Description

4-Thiouracil is a site-specific, photoactivatable probe used to detect RNA structures and nucleic acid-nucleic acid contacts. It absorbs ultraviolet light >300 nm and, in the presence of oxygen, acts as an energy donor to produce singlet oxygen by triplet-triplet energy transfer. The highly reactive oxygen species then reacts readily with 4-thiouracil, leading to the production of uracil and uracil-6-sulfonate, which is fluorescent at a wavelength of ~390 nm. 4-Thiouracil is used as a T. gondii uracil phosphoribosyltransferase substrate to produce 4-thiouridine monophosphate, which can ultimately be incorporated into RNA.

Chemical Properties

yellow powder

Uses

4-Thiouracil is suitable reagent employed in Schneider′s media for the embryos during RNA extraction. It may be employed as reagent for the Northwestern blotting technique.

Uses

4-Thiouracil is a derivative of Uracil (U801000), which is a nitrogenous base in RNA nucleic acid. 4-Thiouracil is used for tagging in cell type-specific RNA isolation from intact complex tissues.

Synthesis Reference(s)

Synthesis, p. 256, 1987 DOI: 10.1055/s-1987-27906

4-THIOURACIL Preparation Products And Raw materials

Raw materials

Ammonium hydroxide Ethanol Phosphorus oxychloride 2-Thiouracil Benzene

Hydrochloric acid Ethylene glycol Acetic acid Sodium hydroxide Sodium hydrosulfide

Magnesium sulfate Iodomethane Carbon

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Preparation Products

4-THIOURACIL Suppliers

Global( 132)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4242	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-18789408387	1057@dideu.com	China	3487	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	CHINA	52867	58
Hunan Jibang Biological Technology Co., LTD	+8613776644403	sales02@kingboomtech.com	China	1806	58

Supplier	Advantage
career henan chemical co	58
Changzhou Ansciep Chemical Co., Ltd.	58
Hubei xin bonus chemical co. LTD	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Shaanxi Dideu Medichem Co. Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Hunan Jibang Biological Technology Co., LTD	58

View Lastest Price from 4-THIOURACIL manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-05-15	4-Thiouracil 591-28-6	US $1.00 / KG	1KG	99%	20T	Shaanxi Dideu Medichem Co. Ltd
	2019-07-06	4-THIOURACIL 591-28-6	US $1.00 / kg	1kg	98%	200kg	Career Henan Chemical Co

4-Thiouracil
591-28-6
US $1.00 / KG
99%
Shaanxi Dideu Medichem Co. Ltd

4-THIOURACIL
591-28-6
US $1.00 / kg
98%
Career Henan Chemical Co

4-THIOURACIL Spectrum

4-THIOURACIL(591-28-6)IR

591-28-6(4-THIOURACIL)Related Search:

4-THIOURACIL 6-AZA-2-THIOURACIL 6-PHENYL-2-THIOURACIL,6-Phenyl-2-thiouracil(4-) 6-AMINO-5-NITROSO-2-THIOURACIL AMMONIUM SALT 6-AMINO-2-THIOURACIL HYDRATE,6-AMINO-2-THIOURACIL MONOHYDRATE

5-METHYL-2-THIOURACIL 5-ETHYL-2-THIOURACIL 6-(TRIFLUOROMETHYL)-2-THIOURACIL DITHIOURACIL 6-BENZYL-2-THIOURACIL

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ETHYL 2-THIOURACIL-5-CARBOXYLATE,5-CARBETHOXY-2-THIOURACIL CRYSTALLINE,5-carboethoxy-2-thiouracil 2-Thiouracil, 6-methyl-,4-METHYL-2-THIOURACIL 98%,6-METHYL-2-THIOURACIL,6-METHYL-2-THIOURACIL,REAGENT 5-BROMO-2-METHOXY-4-(METHYLTHIO)PYRIMIDINE

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4-Thiouracil97% 4-Thiouracil 97% 2(1H)-Pyrimidinone, 3,4-dihydro-4-thioxo- (9CI) 4-Thiouracil ,98% 4-Thioxo-1H-pyrimidin-2-one 2-HYDROXY-4-MERCAPTOPYRIMIDINE / 4-THIOURACIL 4-thiouracyl 4-sulfanylidene-1,2,3,4-tetrahydropyriMidin-2-one 2-Hydroxy-4-mercaptopyrimidine 3,4-Dihydro-4-thioxo-2(1H)-pyrimidinone 4-thioxo-3,4-dihydropyriMidin-2(1H)-one 4-mercaptopyrimidin-2-ol 2(1H)-Pyrimidinone, 3,4-dihydro-4-thioxo- KC 135 Uracil, 4-thio- 4-THIOURACIL 2-HYDROXY-4-MERCAPTOPYRIMIDINE 3,4-Dihydro-4-thioxo-2(1H)-pyrimidinone 4-sulfanylidene-1H-pyrimidin-2-one 2-hydroxypyrimidine-4(3H)-thione 591-28-6 C4H4N2OS Building Blocks Heterocyclic Building Blocks Pyrimidines PYRIMIDINE