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OUABAIN OCTAHYDRATE

OUABAIN OCTAHYDRATE
OUABAIN OCTAHYDRATE structure
CAS No.
11018-89-6
Chemical Name:
OUABAIN OCTAHYDRATE
Synonyms
OUABAIN 8H2O;OUABAIN 8H20;G-Strophantin;STROPHANTHIN G;OUABAIN HYDRATE;OUBAIN OCTAHYDRATE;OUABAIN OCTAHYDRATE;(-)-OUABAIN OCTAHYDRATE;Ouabain octahydrate,96%;Ouabain octahydrate 96%
CBNumber:
CB4469924
Molecular Formula:
C29H60O20
Formula Weight:
728.77
MOL File:
11018-89-6.mol

OUABAIN OCTAHYDRATE Properties

Melting point:
260 °C
storage temp. 
+2C to +8C
solubility 
H2O: 10 mg/mL cold
form 
powder
color 
white
optical activity
[α]25/D 31 to 32.5° in H2O(lit.)
Water Solubility 
Soluble in water.
Sensitive 
Light Sensitive
BRN 
101712
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  T
Risk Statements  23/25-33
Safety Statements  45
RIDADR  UN 1544 6.1/PG 1
WGK Germany  3
RTECS  RN3850000
8
HazardClass  6.1(b)
PackingGroup  III
HS Code  29389090
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger P264, P270, P301+P310, P321, P330,P405, P501
H330 Fatal if inhaled Acute toxicity,inhalation Category 1, 2 Danger P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P311 Call a POISON CENTER or doctor/physician.
P320 Specific treatment is urgent (see … on this label).
P330 Rinse mouth.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.

OUABAIN OCTAHYDRATE price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 4995 Ouabain, Octahydrate 11018-89-6 1gm $119 2018-11-20 Buy
Sigma-Aldrich O3125 Ouabain octahydrate ≥95% (HPLC), powder 11018-89-6 1g $130 2018-11-13 Buy
Alfa Aesar J60724 Ouabain octahydrate, 95% 11018-89-6 1g $280 2018-11-13 Buy
Sigma-Aldrich O3125 Ouabain octahydrate ≥95% (HPLC), powder 11018-89-6 5g $519 2018-11-13 Buy
Sigma-Aldrich O3125 Ouabain octahydrate ≥95% (HPLC), powder 11018-89-6 25g $1710 2018-11-13 Buy

OUABAIN OCTAHYDRATE Chemical Properties,Uses,Production

Chemical Properties

white to off-white crystalline powder

Chemical Properties

Ouabain is a white crystalline solid.

Uses

A cardiac glycoside that inhibits Na(+)/K(+) ATPase. It regulates transcription of MDR (increase, Pgp) and MRP (increase MRP1 and decrease CFTR, cyctic fibrosis transport receptor or cAMP-activated Cl- channel) genes, also alters localization of MRP1.

Uses

antiarrhythmic, cardiotonic, hypertensive, Na/K ATPase inhibitor

Uses

5HT2 receptor antagonist

Potential Exposure

Ouabain, similar to digitoxin, is used to produce rapid digitalization in acute congestive heart failure. Also recommended in treatment of atrial or nodal paroxysmal tachycardia and atrial flutter; enzyme inhibitor.

Shipping

UN1544 Alkaloids, solid, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Purification Methods

It crystallises from water as the octahydrate. Dry it at 130o. It decomposes at 190o when dry. Store it in the dark as it is light sensitive, but it is stable in air. Its solubility (g/100mL) in H2O is 1.3 (~25o), 20 (~100o), and in EtOH it is 1.0 (~25o) and 12.5 (~78o). It is highly TOXIC as it is an inhibitor of cation transport and of Na+ and K+ ATPase. [Beilstein 18/5 V 625.]

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.).

OUABAIN OCTAHYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products


OUABAIN OCTAHYDRATE Suppliers

Global( 74)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) sh@meryer.com China 40275 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 / 800-988-0390
021-67121385 Sales-CN@TCIchemicals.com China 24560 81
Nanjing Chemlin Chemical Co., Ltd 025-83697070
+86-25-83453306 sales@chemlin.com.cn China 19981 64
Chemsky(shanghai)International Co.,Ltd. 021-50135380
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Spectrum Chemical Manufacturing Corp. 021-67601398,18616765336,QQ:3003443155
021-57711696 mkt@spectrumchina.net China 9690 60
Chengdu Ai Keda Chemical Technology Co., Ltd. 4008-755-333 ; 028-86676798 ; 028-86757656
028-86757656 aikeshiji@163.com China 9759 55
Thermo Fisher Scientific 800-810-5118
+86-10-84193589 cnchemical@thermofisher.com China 17448 75
Beijing innoChem Science & Technology Co.,Ltd. 400-810-7969 010-59572699
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