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MKC8866

MKC8866 structure

CAS No.: 1338934-59-0

Chemical Name:: MKC8866

Synonyms: 181697;MKC8866;MKC8866;MKC-8866;IRE-1α inhibitor 1;IRE1 RNase inhibitor 8866;IRE1 RNase inhibitor 8866 (MKC8866;Inositol requiring enzyme 1,inhibit,MKC-8866,IRE1,MKC8866,Inhibitor,MKC 8866;7-hydroxy-6-methoxy-4-methyl-3-(2-morpholino-2-oxoethyl)-2-oxo-2H-chromene-8-carbaldehyde;2H-1-Benzopyran-8-carboxaldehyde, 7-hydroxy-6-methoxy-4-methyl-3-[2-(4-morpholinyl)-2-oxoethyl]-2-oxo-

CBNumber:: CB44796671

Molecular Formula:: C18H19NO7

Molecular Weight:: 361.35

MDL Number:

MOL File:: 1338934-59-0.mol

Last updated:2023-09-20 16:43:00

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MKC8866 Properties

Boiling point	620.0±55.0 °C(Predicted)
Density	1.373±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO:16.67(Max Conc. mg/mL);46.13(Max Conc. mM)
form	A solid
pka	6.20±0.20(Predicted)
FDA UNII	1NZ0YBP9HB

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P280-P305+P351+P338

MKC8866 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Axon Medchem	Axon3223	MKC8866 99%	1338934-59-0	5mg	$115.5	2021-12-16	Buy
Axon Medchem	Axon3223	MKC8866 99%	1338934-59-0	25mg	$401.5	2021-12-16	Buy
ChemScene	CS-0026810	MKC8866 99.87%	1338934-59-0	5mg	$550	2021-12-16	Buy
Axon Medchem	Axon3223	MKC8866 99%	1338934-59-0	2x25mg	$616	2021-12-16	Buy
ChemScene	CS-0026810	MKC8866 99.87%	1338934-59-0	10mg	$850	2021-12-16	Buy

Product number	Packaging	Price	Buy
Axon3223	5mg	$115.5	Buy
Axon3223	25mg	$401.5	Buy
CS-0026810	5mg	$550	Buy
Axon3223	2x25mg	$616	Buy
CS-0026810	10mg	$850	Buy

MKC8866 Chemical Properties,Uses,Production

Biological Activity

MKC8866 (IRE1-IN-8866) is a salicylaldehyde analog, a specific IRE1α RNase inhibitor with IC50 of 0.29 μM against human IRE1α in vitro.

target

Target	Value
hIRE1α (Cell-free assay)	0.29 μM

MKC8866 Preparation Products And Raw materials

Raw materials

Preparation Products

MKC8866 Suppliers

Global( 39)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
ChemShuttle, Inc.	0510-83588313-802 18800520310;	sales@chemshuttle.com	China	3062	62
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4121	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	3444	55
ShangHai Biochempartner Co.,Ltd	17754423994 17754423994	2853530910@QQ.com	China	8011	62
Shanghai Rechem science Co., Ltd.	21-31433387 15618786686	sales@rechemscience.com	China	2981	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Aladdin Scientific	58
ChemShuttle, Inc.	62
Shanghai Lollane Biological Technology Co.,Ltd.	55
Shanghai EFE Biological Technology Co., Ltd.	58
Tianjin Kailiqi Biotechnology Co., Ltd.	55
ShangHai Biochempartner Co.,Ltd	62
Shanghai Rechem science Co., Ltd.	58

MKC8866 Spectrum

MKC8866(1338934-59-0)¹HNMR

1338934-59-0(MKC8866)Related Search:

MKC9989 GSK2656157 7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine MKC3946 ISRIB

MKC8866 2H-1-Benzopyran-8-carboxaldehyde, 7-hydroxy-6-methoxy-4-methyl-3-[2-(4-morpholinyl)-2-oxoethyl]-2-oxo- IRE1 RNase inhibitor 8866 (MKC8866 7-hydroxy-6-methoxy-4-methyl-3-(2-morpholino-2-oxoethyl)-2-oxo-2H-chromene-8-carbaldehyde MKC8866;MKC-8866 181697 IRE1 RNase inhibitor 8866 Inositol requiring enzyme 1,inhibit,MKC-8866,IRE1,MKC8866,Inhibitor,MKC 8866 IRE-1α inhibitor 1 1338934-59-0