ChemicalBook >> CAS DataBase List >>(R)-ADX-47273

(R)-ADX-47273

CAS No.
851881-59-9
Chemical Name:
(R)-ADX-47273
Synonyms
(R)-ADX-47273;Inhibitor,inhibit,mGluR,(R)ADX47273,(R) ADX 47273,Metabotropic glutamate receptors;(4-Fluorophenyl)[(3R)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]methanone;Methanone, (4-fluorophenyl)[(3R)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-
CBNumber:
CB44797012
Molecular Formula:
C20H17F2N3O2
Molecular Weight:
369.36
MDL Number:
MOL File:
851881-59-9.mol
Last updated:2023-05-21 10:59:17

(R)-ADX-47273 Properties

storage temp. Store at -20°C
solubility Soluble in DMSO

(R)-ADX-47273 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0047681 (R)-ADX-47273 99.25% 851881-59-9 5mg $140 2021-12-16 Buy
Biosynth Carbosynth BA166488 (R)-ADX 47273 851881-59-9 10mg $145 2021-12-16 Buy
ChemScene CS-0047681 (R)-ADX-47273 99.25% 851881-59-9 10mg $240 2021-12-16 Buy
AK Scientific 6718CS (4-Fluorophenyl)-[(3R)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl]methanone 851881-59-9 10mg $245 2021-12-16 Buy
Biosynth Carbosynth BA166488 (R)-ADX 47273 851881-59-9 50mg $507.5 2021-12-16 Buy
Product number Packaging Price Buy
CS-0047681 5mg $140 Buy
BA166488 10mg $145 Buy
CS-0047681 10mg $240 Buy
6718CS 10mg $245 Buy
BA166488 50mg $507.5 Buy

(R)-ADX-47273 Chemical Properties,Uses,Production

Description

(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation . mGluR5|168 nM (EC50)

(R)-ADX-47273 (ADX-47273 (5)) is a potent mGluR5 positive allosteric modulator with an EC50 for potentiation of 168 nM and a 9-fold shift of the glutamate response curve at 1 μM[1].

References

[1]. Engers DW, et al. Synthesis, SAR and unanticipated pharmacological profiles of analogues of the mGluR5 ago-potentiator ADX-47273. ChemMedChem. 2009 Apr;4(4):505-11.

(R)-ADX-47273 Preparation Products And Raw materials

Raw materials

Preparation Products

(R)-ADX-47273 Suppliers

Global( 17)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11681 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686 sales@rechemscience.com China 2982 58
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720 chaolaichem@foxmail.com China 7565 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9730 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Jingmo (Xiamen) Biotechnology Co., Ltd 13621943973 13515979683 sales@jamxmpharmatech.com China 1079 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5132 58
(R)-ADX-47273 (4-Fluorophenyl)[(3R)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]methanone Methanone, (4-fluorophenyl)[(3R)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]- Inhibitor,inhibit,mGluR,(R)ADX47273,(R) ADX 47273,Metabotropic glutamate receptors 851881-59-9