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GSK4028

GSK4028 structure

CAS No.: 2079886-19-2

Chemical Name:: GSK4028

Synonyms: GSK4028;3(2H)-Pyridazinone, 4-bromo-2-methyl-5-[[(3S,5S)-1-methyl-5-phenyl-3-piperidinyl]amino]-

CBNumber:: CB44797067

Molecular Formula:: C17H21BrN4O

Molecular Weight:: 377.28

MDL Number:

MOL File:: 2079886-19-2.mol

Last updated:2023-05-21 10:59:17

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GSK4028 Properties

Boiling point	450.3±55.0 °C(Predicted)
Density	1.45±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
pka	9.58±0.10(Predicted)

GSK4028 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0058953	GSK4028 98.11%	2079886-19-2	5mg	$550	2021-12-16	Buy
ChemScene	CS-0058953	GSK4028 98.11%	2079886-19-2	10mg	$850	2021-12-16	Buy
ChemScene	CS-0058953	GSK4028 98.11%	2079886-19-2	25mg	$1750	2021-12-16	Buy
ChemScene	CS-0058953	GSK4028 98.11%	2079886-19-2	50mg	$2750	2021-12-16	Buy
ChemScene	CS-0058953	GSK4028 98.11%	2079886-19-2	100mg	$3950	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-0058953	5mg	$550	Buy
CS-0058953	10mg	$850	Buy
CS-0058953	25mg	$1750	Buy
CS-0058953	50mg	$2750	Buy
CS-0058953	100mg	$3950	Buy

GSK4028 Chemical Properties,Uses,Production

Description

GSK4028 is the enantiomeric negative control of GSK4027, which is a PCAF/GCN5 bromodomain chemical probe, the pIC50 of GSK4028 is 4.9 in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay.

GSK4028 is the enantiomeric negative control of GSK4027, which is a PCAF/GCN5 bromodomain chemical probe, the pIC50 of GSK4028 is 4.9. GSK4028 also demonstrates potency toward BRD4 BD1 and BRD9 inTR-FRET assay with pIC50s of <4.3 and 4.5±0.13, respectively[1].

References

[1]. Humphreys PG, et al. Discovery of a Potent, Cell Penetrant, and Selective p300/CBP-Associated Factor (PCAF)/General Control Nonderepressible 5 (GCN5) Bromodomain Chemical Probe. J Med Chem. 2017 Jan 26;60(2):695-709.

GSK4028 Preparation Products And Raw materials

Raw materials

Preparation Products

GSK4028 Suppliers

Global( 9)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Fan De(Beijing) Biotechnology Co., Ltd.	15911056312	liming@bio-fount.com	China	9730	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Shanghai hongqu biomedical technology co. LTD	88888888888	hongquchem@qq.com	China	5132	58
Kaifeng Mingren Pharmaceutical Co.,LTD	0371-65741762	sales@hasunny.com	China	2380	58
InvivoChem	13549236410	sales@invivochem.cn	China	6712	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
InvivoChem	58
Aladdin Scientific	58
Fan De(Beijing) Biotechnology Co., Ltd.	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
Shanghai hongqu biomedical technology co. LTD	58
Kaifeng Mingren Pharmaceutical Co.,LTD	58
InvivoChem	58

GSK4028 3(2H)-Pyridazinone, 4-bromo-2-methyl-5-[[(3S,5S)-1-methyl-5-phenyl-3-piperidinyl]amino]- 2079886-19-2