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AROTINOLOL

AROTINOLOL structure

CAS No.: 68377-92-4

Chemical Name:: AROTINOLOL

Synonyms: Arot-API;Arotinolo;NSC 317940;Arottnolol;AROTINOLOL;Arotinolol (Almarl);Arotinolol free base;AROTINOLOL USP/EP/BP;5-(2-((3-(tert-Butylamino);Arotinolol Solution, 100ppm

CBNumber:: CB4486237

Molecular Formula:: C15H21N3O2S3

Molecular Weight:: 371.54

MDL Number:: MFCD00865895

MOL File:: 68377-92-4.mol

MSDS File:: SDS

Last updated:2023-05-18 11:31:19

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AROTINOLOL Properties

Melting point	148-149°
Boiling point	599.8±60.0 °C(Predicted)
Density	1.35
storage temp.	2-8°C(protect from light)
solubility	DMSO (Slightly), Methanol (Slightly)
pka	13.71±0.20(Predicted)
form	Solid
color	Off-White to Pale Yellow
FDA UNII	394E3P3B99

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

AROTINOLOL price More Price(19)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	A771500	Arotinolol	68377-92-4	100mg	$185	2021-12-16	Buy
Biosynth Carbosynth	FA41108	Arotinolol	68377-92-4	25mg	$200	2021-12-16	Buy
ChemScene	CS-0102757	Arotinolol 98.18%	68377-92-4	5mg	$90	2021-12-16	Buy
AK Scientific	K136	Arotinolol	68377-92-4	5mg	$95	2021-12-16	Buy
ChemScene	CS-0102757	Arotinolol 98.18%	68377-92-4	10mg	$150	2021-12-16	Buy

Product number	Packaging	Price	Buy
A771500	100mg	$185	Buy
FA41108	25mg	$200	Buy
CS-0102757	5mg	$90	Buy
K136	5mg	$95	Buy
CS-0102757	10mg	$150	Buy

AROTINOLOL Chemical Properties,Uses,Production

Originator

Arotinolol,ZYF Pharm

Uses

Arotinolol is both and alpha- and beta-adrenoceptor antagonist and is used to treat essential tremors and hypertension.

Definition

ChEBI: Arotinolol is a member of thiophenes and an aromatic amide.

Manufacturing Process

To a solution of 2-mercapto-4-(5'-carbamoyl-2'-thiophenyl)thiazole, 3.2 g in 20 ml of 0.3 % aqueous sodium hydroxide solution, 1-chloro-3-tbutylaminopropanol, 12.64 g in 20 ml of methanol was added, while the temperature was maintained at 20°C.
The reaction solution was stirred at room temperature for 4 h, and then condensed to a half volume in vacuo. The residual solution, added with 100 ml of water, was extracted with chloroform. The chloroform extract was washed with water, dried over anhydrous magnesium sulfate and evaporated in vacuo to give 4.8 g of 2-(3'-t-butylamino-2'-hydroxypropylthio)-4-(5'-carbamoyl-2'- thiophenyl)thiazole, as crystals, melting point 234°-235.5°C (dec., recrystallized from methanol/water).
In practice it is usually used as hydrochloride.

Therapeutic Function

Beta-adrenergic blocker

AROTINOLOL Preparation Products And Raw materials

Raw materials

Sodium hydroxide

Preparation Products

AROTINOLOL Suppliers

Global( 83)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9320	58
Shijiazhuang Gantuo Biotechnology Co., Ltd	+8613373514458	gantuo02@cngantuo.com	China	218	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29220	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418684 +8618949823763	sales@tnjchem.com	China	25363	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24738	58
ZHEJIANG JIUZHOU CHEM CO., LTD	+86-0576225566889 +86-13454675544	admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com	China	20000	58
Hebei Miaoyin Technology Co.,Ltd	+86-17367732028 +86-17367732028	kathy@hbyinsheng.com	China	3582	58

Supplier	Advantage
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58
Shaanxi Dideu Medichem Co. Ltd	58
Shijiazhuang Gantuo Biotechnology Co., Ltd	58
Dideu Industries Group Limited	58
InvivoChem	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
LEAP CHEM CO., LTD.	58
ZHEJIANG JIUZHOU CHEM CO., LTD	58
Hebei Miaoyin Technology Co.,Ltd	58

View Lastest Price from AROTINOLOL manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-06-26	Arotinolol 68377-92-4	US $200.00 / kg	1kg	99%	1000kg/Month	Hebei Mingeng Biotechnology Co., Ltd
2023-04-11	Arotinolol 68377-92-4	US $100.00 / KG	25KG	99%	1000 Kilogram/Kilograms per Week	Shijiazhuang Gantuo Biotechnology Co., Ltd
2021-08-12	AROTINOLOL USP/EP/BP 68377-92-4	US $1.10 / g	1g	99.9%	100 Tons min	Dideu Industries Group Limited

Arotinolol
68377-92-4
US $200.00 / kg
99%
Hebei Mingeng Biotechnology Co., Ltd

Arotinolol
68377-92-4
US $100.00 / KG
99%
Shijiazhuang Gantuo Biotechnology Co., Ltd

AROTINOLOL USP/EP/BP
68377-92-4
US $1.10 / g
99.9%
Dideu Industries Group Limited

68377-92-4(AROTINOLOL)Related Search:

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(-)-R-Arotinolol S-Arotinolol HCl R-Arotinolol HCl

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AROTINOLOL Arottnolol 2-(3-tert-Butylamino-2-hydroxypropylthio)-4-(5-carbamoyl-2-thienyl)thiazole 2-Thiophenecarboxamide, 5-[2-[[3-[(1,1-dimethylethyl)amino]-2-hydroxypropyl]thio]-4-thiazolyl]- 2-Thiophenecarboxamide, 5-[2-[[3-[(1,1-dimethylethyl)amino]-2-hydroxypropyl]thio]-4-thiazolyl]-, (+-)- NSC 317940 5-[2-[[3-(tert-butylamino)-2-hydroxy-propyl]thio]thiazol-4-yl]thiophene-2-carboxamide 5-[2-[3-(tert-butylamino)-2-hydroxy-propyl]sulfanyl-1,3-thiazol-4-yl]thiophene-2-carboxamide 5-[2-[3-(tert-butylamino)-2-hydroxypropyl]sulfanyl-1,3-thiazol-4-yl]thiophene-2-carboxamide 5-(2-((3-(tert-Butylamino) Arotinolo Arotinolol Solution, 1000ppm Arotinolol Solution, 100ppm Arotinolol free base AROTINOLOL USP/EP/BP Arotinolol (Almarl) Arot-API 68377-92-4 C15H21N3O2S3