DIMETHYL 4-HYDROXYPHTHALATE
- CAS No.
- 22479-95-4
- Chemical Name:
- DIMETHYL 4-HYDROXYPHTHALATE
- Synonyms
- Einecs 245-023-9;DIMETHYL 4-HYDROXYPHTHALATE;4-hydroxybenzene-1,2-dicarboxylate;dimethyl 4-hydroxybenzene-1,2-dioate;4-HYDROXYPHTHALIC ACID DIMETHYL ESTER;dimethyl 4-hydroxybenzene-1,2-dicarboxylate;Dimethyl 4-hydroxy-1,2-benzenedicarboxylate;1,2-diMethyl 4-hydroxybenzene-1,2-dicarboxylate;4-hydroxybenzene-1,2-dicarboxylic acid dimethyl ester;1,2-Benzenedicarboxylic acid, 4-hydroxy-, 1,2-dimethyl ester
- CBNumber:
- CB4489263
- Molecular Formula:
- C10H10O5
- Molecular Weight:
- 210.18
- MDL Number:
- MFCD00060092
- MOL File:
- 22479-95-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Dimethyl4-Hydroxyphthalate | D368105 | 100mg | $65 |
| Dimethyl 4-hydroxyphthalate | FD144427 | 250mg | $100 |
| Dimethyl4-hydroxyphthalate | 1346AB | 5g | $150 |
| Dimethyl 4-hydroxyphthalate | FD144427 | 500mg | $150 |
| Dimethyl 4-hydroxyphthalate | FD144427 | 1g | $250 |
| More product size | |||
| Melting point | 110-111℃ |
|---|---|
| Boiling point | 330.6±22.0℃ (760 Torr) |
| Density | 1.284±0.06 g/cm3 (20 ºC 760 Torr) |
| Flash point | 129.3±15.8℃ |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 7.54±0.18(Predicted) |
| Appearance | Off-white to light yellow Solid |
| FDA UNII | R8KP9I1QJ9 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
DIMETHYL 4-HYDROXYPHTHALATE price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | D368105 | Dimethyl4-Hydroxyphthalate | 22479-95-4 | 100mg | $65 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD144427 | Dimethyl 4-hydroxyphthalate | 22479-95-4 | 250mg | $100 | 2021-12-16 | Buy |
| AK Scientific | 1346AB | Dimethyl4-hydroxyphthalate | 22479-95-4 | 5g | $150 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD144427 | Dimethyl 4-hydroxyphthalate | 22479-95-4 | 500mg | $150 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD144427 | Dimethyl 4-hydroxyphthalate | 22479-95-4 | 1g | $250 | 2021-12-16 | Buy |
DIMETHYL 4-HYDROXYPHTHALATE Chemical Properties,Uses,Production
Chemical Properties
white solid
Synthesis Reference(s)
Tetrahedron Letters, 18, p. 611, 1977 DOI: 10.1016/S0040-4039(01)92706-6
Synthesis
67-56-1
610-35-5
22479-95-4
General procedure for the synthesis of dimethyl 4-hydroxyphthalate from methanol and 4-hydroxyphthalic acid: 1. thionyl chloride (20 mL) was slowly added to a methanol (100 mL) solution of 4-hydroxyphthalic acid (20 g, 110 mmol). 2. The reaction mixture was stirred at 0 °C, then warmed to 80 °C and held for 4 hours. 3. Upon completion of the reaction, the volatiles were removed by distillation under reduced pressure to give dimethyl 4-hydroxyphthalate (C1-2) as a white solid (23 g, yield: 99%), which could be used in the next step without further purification. 4. 4. The structure of the product was confirmed by 1H NMR (CDCl3, 400 MHz) and mass spectrometry (ESI): 1H NMR δ 7.77 (d, J = 8.8 Hz, 1H), 7.03 (d, J = 2 Hz, 1H), 6.95 (dd, J = 8.4 and 2.0 Hz, 1H), 3.93 (s, 3H), 3.88 (s, 3H); MS ( ESI) m/z 211 ([M+H]+).
References
[1] Patent: WO2014/18866, 2014, A1. Location in patent: Paragraph 00175; 00176
[2] ChemMedChem, 2010, vol. 5, # 2, p. 213 - 231
[3] Chemistry of Materials, 2014, vol. 26, # 14, p. 4151 - 4162
[4] Patent: US2015/56305, 2015, A1. Location in patent: Paragraph 0270; 0271; 0387; 0388
[5] Chemical Science, 2018, vol. 9, # 24, p. 5312 - 5321
DIMETHYL 4-HYDROXYPHTHALATE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21592 | 55 |
| Chembon Pharmaceutical Co., Ltd. | +86-28-8425-2981 | CHINA | 722 | 55 | |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Jinan Shengqi pharmaceutical Co,Ltd | 86+18663751872 | christine@shengqipharm.com | CHINA | 491 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2949 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from DIMETHYL 4-HYDROXYPHTHALATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-03 | DIMETHYL 4-HYDROXYPHTHALATE
22479-95-4
|
US $1.00 / KG | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- DIMETHYL 4-HYDROXYPHTHALATE
22479-95-4
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
