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MONOBEHENIN

CAS No.
30233-64-8
Chemical Name:
MONOBEHENIN
Synonyms
MONOBEHENIN;1-MONOBEHENIN;KeMester 6500;MONODOCOSANOIN;Glyceryl monobehenate;Docosanoin, Mono- (7CI);Monostearin Impurity 37;Behenic acid monoglyceride;n-Docosanoicacidglycerolester;NomINCI:Glyceryl(mono)behenate
CBNumber:
CB4489612
Molecular Formula:
C25H50O4
Molecular Weight:
414.66
MDL Number:
MFCD00273075
MOL File:
30233-64-8.mol
Last updated:2023-09-07 14:58:50

MONOBEHENIN Properties

Density 0.93[at 20℃]
vapor pressure 0.001Pa at 25℃
solubility Soluble, when heated, in chloroform and dichloromethane and in many organic solvents; slightly soluble in hot ethanol (96%); practically insoluble in cold ethanol (95%), hexane, mineral oil, and water.
form A solid
Water Solubility 100ng/L at 25℃
LogP 8.58 at 25℃
FDA UNII A626UU0W2A
EPA Substance Registry System Docosanoic acid, monoester with 1,2,3-propanetriol (30233-64-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

MONOBEHENIN price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-B0798 Monobehenin 30233-64-8 100mg $150 2021-12-16 Buy
ChemScene CS-B0798 Monobehenin 30233-64-8 500mg $450 2021-12-16 Buy
Product number Packaging Price Buy
CS-B0798 100mg $150 Buy
CS-B0798 500mg $450 Buy

MONOBEHENIN Chemical Properties,Uses,Production

Chemical Properties

Glyceryl behenate occurs as a fine white-yellow powder, as a hard waxy mass or pellet, or as white or almost white unctuous flakes. It has a faint odor.

Definition

ChEBI: 1-behenoylglycerol is a fatty acid ester resulting from the formal condensation of the hydroxy group at position-1 of glycerol with the carboxy group of docosanoic acid. It has a role as a plant metabolite and an antineoplastic agent. It is a 1-monoglyceride and a fatty acid ester. It is functionally related to a glycerol and a docosanoic acid.

Production Methods

Glyceryl behenate is prepared by the esterification of glycerin by behenic acid (C22 fatty acid) without the use of catalysts. In the case of Compritol 888 ATO (Gattefosse′), raw materials used are of vegetable origin, and the esterified material is atomized by spraycooling.

Pharmaceutical Applications

Glyceryl behenate is used in cosmetics, foods, and oral pharmaceutical formulations.
In pharmaceutical formulations, glyceryl behenate is mainly used as a lubricant in the preparation of oral tablets and capsules. It has good binding properties, it does not affect tablet hardness and is unaffected by mixing or production parameters. Glyceryl behenate has been investigated for the encapsulation of various drugs such as retinoids. It has also been investigated for use in the preparation of sustained-release tablets; as a matrix-forming agent for the controlled release of water-soluble drugs; and it can also be used as a hot-melt coating agent sprayed onto a powder or drug-loaded sugar beads and granules. It may also be incorporated via extrusion/spheronization into pellets, which can be further compressed into tablets.
Glyceryl behenate is used in oral enteric-coated pellets, powders and suspensions. It is also used in controlled, extended-release and orally disintegrating tablets. For oral preparations, glyceryl behenate forms a lipidic matrix for sustained-release formulations. It has been used along with acid-soluble or swellable polymers to mask the bitter or unpleasant taste of the medicament with improved palatability.
Glyceryl behenate has been used for the preparation of ophthalmic inserts.
In cosmetics, glyceryl behenate is used as a skin conditioning agent, emollient and viscosity-increasing agent in emulsions. It also improves the heat stability of emulsions and is a gelifying agent for various oils. For topical formulations, it is used as a thickening agent for oily phases. It is also used as a surfactant or emulsifying agent.

Safety

Glyceryl behenate is used in cosmetics, foods and oral pharmaceutical formulations, and is generally regarded as a relatively nonirritant and nontoxic material. The US Cosmetic Ingredients Review Expert Panel evaluated glyceryl behenate and concluded that it is safe for use in cosmetic formulations in present practices of use and concentration.
LD50 (mouse, oral): 5 g/kg

storage

Glyceryl behenate should be stored in a tightly closed container, at a temperature less than 35°C.

Regulatory Status

GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral capsules, tablets, and suspensions). Included in the Canadian List of Acceptable Non-medicinal Ingredients.

MONOBEHENIN Preparation Products And Raw materials

Raw materials

Preparation Products

MONOBEHENIN Suppliers

Global( 53)Suppliers
Supplier Tel Email Country ProdList Advantage
Jiangxi Alpha Hi-tech Pharmaceutical Co., Ltd
510-85010237 overseamarketing@alphahi-tech.com CHINA 41 58
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12452 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5909 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Univar Solutions(China) Co., Ltd.
+8615902132654 ivy.zhuang@univarsolutions.com China 654 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196 sale04@alfachem.cn China 12321 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hebei Zhanyao Biotechnology Co. Ltd
15369953316 +8615369953316 admin@zhanyaobio.com China 2136 58
Wuhan Fortuna Chemical Co., Ltd
+86-27-59207850 +86-13986145403 info@fortunachem.com China 5981 58

View Lastest Price from MONOBEHENIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
MONOBEHENIN pictures 2023-09-07 MONOBEHENIN
30233-64-8
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
Monobehenin pictures 2023-08-31 Monobehenin
30233-64-8
US $100.00-100.00 / kg 1kg 99 5000 Hebei Fengqiang Trading Co., LTD
Glyceryl Behenate pictures 2023-05-11 Glyceryl Behenate
30233-64-8
US $49.00 / KG 1KG 99%,CP,USP 20MT JIANGXI ALPHA HI-TECH PHARMACEUTICAL CO., LTD
  • MONOBEHENIN pictures
  • MONOBEHENIN
    30233-64-8
  • US $0.00 / KG
  • 99%
  • Hebei Mojin Biotechnology Co., Ltd
  • Monobehenin pictures
  • Monobehenin
    30233-64-8
  • US $100.00-100.00 / kg
  • 99
  • Hebei Fengqiang Trading Co., LTD
  • Glyceryl Behenate pictures
  • Glyceryl Behenate
    30233-64-8
  • US $49.00 / KG
  • 99%,CP,USP
  • JIANGXI ALPHA HI-TECH PHARMACEUTICAL CO., LTD
docosanoic acid, monoester with glycerol n-Docosanoicacidglycerolester NomINCI:Glyceryl(mono)behenate Docosansure, Monoester mit Glycerin Glyceryl monobehenate Docosanoic acid, Monoester with glycerol (8CI) Docosanoin, Mono- (7CI) KeMester 6500 1-MONOBEHENIN MONODOCOSANOIN MONOBEHENIN docosanoicacid,monoesterwith1,2,3-propanetriol Docosanoicacidmonoesterwith1,2,3-propanetriol Behenic acid monoglyceride Glyceryl Behenate (pharmaceutical grade) Monobehenin,inhibit,Inhibitor,Bacterial Monostearin Impurity 37 30233-64-8 C25H50O4