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L-Lysine

L-Lysine
L-Lysine structure
CAS No.
56-87-1
Chemical Name:
L-Lysine
Synonyms
Lys;LYSINE;L-Lys-OH;L-LYSINE;H-LYS-OH;FEMA 3847;Aminutrin;lysineacid;L-LysineUSP;Lysine acid
CBNumber:
CB4492106
Molecular Formula:
C6H14N2O2
Formula Weight:
146.19
MOL File:
56-87-1.mol

L-Lysine Properties

Melting point:
215 °C (dec.)(lit.)
alpha 
D20 +14.6° (c = 6.5); D23 +25.9° (c = 2 in 6.0N HCl)
Boiling point:
265.81°C (rough estimate)
Density 
1.1360 (rough estimate)
refractive index 
26 ° (C=2, 5mol/L HCl)
FEMA 
3847 | L-LYSINE
storage temp. 
Store at RT.
solubility 
H2O: 0.1 g/mL, clear, colorless
pka
2.16(at 25℃)
form 
Powder or Crystals
color 
White to light yellow
optical activity
[α]20/D +26.0±1.0°, c = 2% in 6 M HCl
Water Solubility 
Soluble in water. Insoluble in ethanol, ethyl ether, acetone, benzene and common neutral solvent.
Merck 
14,5636
JECFA Number
1439
BRN 
1722531
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
KDXKERNSBIXSRK-YFKPBYRVSA-N
CAS DataBase Reference
56-87-1(CAS DataBase Reference)
NIST Chemistry Reference
Lysine(56-87-1)
EPA Substance Registry System
L-Lysine(56-87-1)

SAFETY

Hazard Codes  Xi
Safety Statements  24/25
WGK Germany  3
RTECS  OL5540000
TSCA  Yes
HS Code  29224110
Hazardous Substances Data 56-87-1(Hazardous Substances Data)

L-Lysine price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 23128 L-Lysine analytical standard 56-87-1 100mg $50.7 2018-11-13 Buy
Sigma-Aldrich 62840 L-Lysine crystallized, ≥98.0% (NT) 56-87-1 25g-f $99.9 2018-11-13 Buy
TCI Chemical L0129 L-(+)-Lysine >97.0%(T) 56-87-1 5g $28 2018-11-22 Buy
TCI Chemical L0129 L-(+)-Lysine >97.0%(T) 56-87-1 25g $74 2018-11-22 Buy
Alfa Aesar J62225 L-Lysine, 98% 56-87-1 25g $67.1 2018-11-13 Buy

L-Lysine Chemical Properties,Uses,Production

Chemical Properties

White to pale yellow crystalline powder

Uses

Essential amino acid for human development. Lysine residues are useful in many cellular processes, due to their ability to accept a wide variety of post-translational modifications.

Uses

A moderate serotonin antagonist and essential amino acid.

Uses

lysine is a skin-conditioning amino acid.

Definition

ChEBI: An L-alpha-amino acid; the L-isomer of lysine.

Biotechnological Production

C. glutamicum and, to a lesser extent, E. coli are the main organisms used today for industrial L-lysine production. The first L-producing strains based on C. glutamicum were reported in 1961, and those based on E. coli in 1995. The advantages of using E. coli versus C. glutamicum include the achievement of higher growth rates at higher fermentation temperatures. The formation of lysine is highly influenced by two enzymes, aspartate kinase (AK) and homoserine dehydrogenase (HDH). AK converts aspartate into aspartate semialdehyde, and is highly feedback-inhibited by lysine and threonine. HDH converts aspartate semialdehyde into homoserine, which is an intermediate for the biosynthesis of threonine, methionine, and isoleucine. L-Lysine–producing strains therefore often contain a deregulated AK and/or a reduced activity HDH. Despite the improvement of the flux from aspartate towards lysine, the availability of key metabolites from the central metabolic pathways is also essential. Here the formation of oxaloacetate directly from phosphoenol pyruvate or via pyruvate is essential for the carbon yield as some unnecessary cycles are included. For example, inactivation of the enzyme phosphoenol pyruvate carboxykinase, which catalyzes the reverse reaction from oxaloacetate to phosphoenol pyruvate gave an improvement in lysine formation. By overexpression of pyruvate carboxylase, the conversion yield of glucose to lysine could be increased by 50 %. With a synthetic lysine hyperproducing strain, containing 12 defined modifications from the wild type, a carbon yield of 0.55 g/g and a product titer of 120 g/L over 30 h fermentation could be obtained.
Today, however, the main commercial process for L-lysine remains the fermentation of C. glutamicum. This is performed in fed-batch mode in large-scale fermenters of up to 500 m3 volume, with production capacities in excess of 100,000 tonnes. The commercial manufacturing process has been comprehensively described by Pfefferle.

Safety Profile

An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Crystallise L-lysine from aqueous EtOH. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2097-2122 1961, Kearley & Ingersoll J Am Chem Soc 73 5783 1951, Beilstein 4 IV 2717.]

L-Lysine Preparation Products And Raw materials

Raw materials

Preparation Products


L-Lysine Suppliers

Global( 383)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19918 60
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21954 58
Shanghai Bojing Chemical Co.,Ltd.
+86-21-37122233
+86-21-37127788 Candy@bj-chem.com CHINA 495 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32457 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 E-mail:sales03@shyrchem.com
+86-21-34979012 sales03@shyrchem.com CHINA 661 60
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1730 55
Chengdu Biopurify Phytochemicals Ltd.
18080483897
maggie@biopurify.com CHINA 2236 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24001 58

View Lastest Price from L-Lysine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-02 L-Lysine Base
56-87-1
US $20.00 / KG 10KG 98% 100kg career henan chemical co
2018-07-30 L-Lysine
56-87-1
US $100.00 / KG 1KG 99% Customized career henan chemical co

L-Lysine Spectrum


56-87-1(L-Lysine)Related Search:

L-Phenylalanine (2S,3S)-2-Amino-3-methylpentanoic acid L-Threonine BOC-N-EPSILON-TFA-L-LYSINE,BOC-N-EPSILON-TRIFLUOROACETYL-L-LYSINE,BOC-N-EPSILON-TFA-L-LYSINE,BOC-N-EPSILON-TRIFLUOROACETYL-L-LYSINE BOC-N-EPSILON-NICOTINOYL-L-LYSINE,BOC-N-EPSILON-NICOTINOYL-L-LYSINE BOC-N-EPSILON-FMOC-L-LYSINE METHYL ESTER,BOC-N-EPSILON-FMOC-L-LYSINE METHYL ESTER BOC-N-ALPHA-METHYL-N-EPSILON-Z-L-LYSINE,BOC-N-ALPHA-METHYL-N-EPSILON-Z-L-LYSINE BOC-N-EPSILON-(2-CHLORO-Z)-D-LYSINE,BOC-N-EPSILON-(2-CHLORO-Z)-D-LYSINE BOC-N-EPSILON-Z-D-LYSINE,BOC-N-EPSILON-Z-D-LYSINE BOC-N-EPSILON-DIMETHYL-L-LYSINE,BOC-N-EPSILON-DIMETHYL-L-LYSINE Theophylline lysine BOC-N-EPSILON-(2-CHLOROBENZYLOXYCARBONYL)-L-LYSINE-4-(OXYMETHYL)-PHENYLACETAMIDOMETHYL RESIN,BOC-N-EPSILON-(2-CHLOROBENZYLOXYCARBONYL)-L-LYSINE-P-METHYLBENZHYDRYLAMINE RESIN,BOC-N-EPSILON-2-CHLORO-Z-L-LYSINE 4-OXYMETHYLPHENYLACETAMIDOMETHYL RESIN,BOC-N-EPSILON-2-CHLORO-Z-L-LYSINE MERRIFIELD RESIN,BOC-N-EPSILON-(2-CHLOROBENZYLOXYCARBONYL)-L-LYSINE-4-(OXYMETHYL)-PHENYLACETAMIDOMETHYL RESIN,BOC-N-EPSILON-(2-CHLOROBENZYLOXYCARBONYL)-L-LYSINE-P-METHYLBENZHYDRYLAMINE RESIN,BOC-N-EPSILON-2-CHLORO-Z-L- BOC-N-EPSILON-FORMYL-L-LYSINE,BOC-N-EPSILON-FORMYL-L-LYSINE BOC-N-EPSILON-FORMYL-L-LYSINE,BOC-N-EPSILON-FORMYL-L-LYSINE BOC-N-EPSILON-2-CHLORO-Z-L-LYSINE T-BUTYLAMINE,BOC-N-EPSILON-2-CHLORO-Z-L-LYSINE T-BUTYLAMINE BOC-N-EPSILON-2-BROMO-Z-L-LYSINE,BOC-N-EPSILON-2-BROMO-Z-L-LYSINE BOC-N-EPSILON-(2-CHLOROBENZYLOXYCARBONYL)-D-LYSINE-4-(OXYMETHYL)-PHENYLACETAMIDOMETHYL RESIN,BOC-N-EPSILON-(2-CHLOROBENZYLOXYCARBONYL)-D-LYSINE-MERRIFIELD RESIN,BOC-N-EPSILON-2-CHLORO-Z-D-LYSINE MERRIFIELD RESIN,BOC-N-EPSILON-2-CHLORO-Z-D-LYSINE 4-OXYMETHYLPHENYLACETAMIDOMETHYL RESIN,BOC-N-EPSILON-2-CHLORO-Z-D-LYSINE 4-OXYMETHYLPHENYLACETAMIDOMETHYL RESIN,BOC-N-EPSILON-(2-CHLOROBENZYLOXYCARBONYL)-D-LYSINE-4-(OXYMETHYL)-PHENYLACETAMIDOMETHYL RESIN,BOC-N-EPSILON-(2-CHLOROBENZYLOXYCARBONYL)-D-LYSI BOC-N-EPSILON-CARBAMOYL-L-LYSINE,BOC-N-EPSILON-CARBAMOYL-L-LYSINE

  • L - LYSINE FREE BASE (ANHYDROUS)
  • L-Lizine cormob crystalline
  • L-LYSINE (BASE) pure
  • L-LYSINE BASE MONOHYDRATE pure
  • L-Lysine,98+%
  • L-LYSINE CRYST.RESEARCH GRADE
  • L-Lysine,(S)-2,6-Diaminocaproic acid
  • LYSINE, L-(+)-(P)
  • (S)-2,6-diaMinohexanoic acid hydrate
  • (S)-a,e-Diaminocaproic acid
  • Aminutrin, 6-amino-
  • L-Lysine (9CI)
  • (2S)-2,6-Diaminocaproic acid, (2S)-2,6-Diaminohexanoic acid
  • L-Lysine crystallized, >=98.0% (NT)
  • L-Lysine Vetec(TM) reagent grade, >=98%
  • NEODIMIUM STAND
  • L-Lys-OH
  • L-Lysine≥ 99% (Titration)
  • (S)-2,6-DIAMINOCAPROIC ACID
  • (S)-(+)-LYSINE
  • LYSINE
  • LYSINE, L-(+)-
  • L-(+)-LYSINE
  • L-Norleucine, 6-amino-
  • Lysine, L- (8CI)
  • L-LysineUSP
  • (S)-2,6-Diaminohexanoic acid
  • L-(+)-LYSINE 50% SOLUTION
  • L-LYSINE
  • L-LYSINE BASE
  • H-LYS-OH
  • FEMA 3847
  • 2,6-DIAMINOCAPROIC ACID
  • (S)-alpha,epsilon-Diaminocaproic acid
  • 2,6-Diaminohexanoic acid
  • 2,6-diaminohexanoicacid
  • alpha,epsilon-Diaminocaproic acid
  • alpha,epsilon-diaminocaproicacid
  • alpha-Lysine
  • Aminutrin
  • Hexanoic acid, 2,6-diamino-, (S)-
  • L-,-Diaminocar-proicacid
  • L-H2N(CH2)4CH(NH2)COOH
  • L-Lysine, l.s.
  • Lys
  • lys(iupacabbreviation)
  • Lysine acid
  • lysineacid
  • L-Lysine Free Base
  • L-LYSINE NON-ANIMAL SOURCE, CELL CULTURE TESTED
  • L-LYSINE, 97% (98% EE/GLC)
  • L(+)-LYSINE-1-HYDRATE BIOSYNTH
  • L-LYSINE SOLUTION, 50% IN WATER
  • L-LYSIN, KRISTALLISIERT
  • L-LYSINE MONOHYDRATE 98%
  • L-Lysine~97%
  • L-Lysine50%SolutionInWater
  • L-Lysine (non-medicinal)
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