ChemicalBook >> CAS DataBase List >>MERBARONE
MERBARONE
- CAS No.
- 97534-21-9
- Chemical Name:
- MERBARONE
- Synonyms
- RLBN1001;RLBN-1001;MERBARONE;NSC-336628;Merbarone - CAS 97534-21-9 - Calbiochem;5-(N-PHENYLCARBAMOYL)-2-THIOBARBITURIC ACID;5-(N-PHENYLCARBOXAMIDO)-2-THIOBARBITURIC ACID;5-(N-Phenylcarbamoyl)-2-thiobarbituric acid, NSC-336628;hexahydro-4,6-dioxo-n-phenyl-2-thioxo-5-pyrimidinecarboxamid;4,6-dioxo-N-phenyl-2-sulfanylidene-1,3-diazinane-5-carboxamide
- CBNumber:
- CB4494665
- Molecular Formula:
- C11H9N3O3S
- Molecular Weight:
- 263.27
- MDL Number:
- MFCD00866337
- MOL File:
- 97534-21-9.mol
Last updated:2023-05-18 11:31:16
| Density | 1.51±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | 2-8°C |
| solubility | DMSO: >5mg/mL |
| form | solid |
| pka | -2.16±0.20(Predicted) |
| FDA UNII | YWB9IF596V |
MERBARONE price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M2070 | Merbarone ≥98% (HPLC), solid | 97534-21-9 | 25mg | $161 | 2024-03-01 | Buy |
| Sigma-Aldrich | 445800 | Merbarone | 97534-21-9 | 25mg | $144 | 2024-03-01 | Buy |
| Usbiological | 454363 | Merbarone | 97534-21-9 | 25mg | $375 | 2021-12-16 | Buy |
| TRC | M800603 | Merbarone | 97534-21-9 | 25mg | $100 | 2021-12-16 | Buy |
| ChemScene | CS-0014735 | Merbarone ≥99.0% | 97534-21-9 | 5mg | $90 | 2021-12-16 | Buy |
MERBARONE Chemical Properties,Uses,Production
Uses
Merbarone has been used to study its effect on the occurrence of DNA lesions.
General Description
A cell-permeable anticancer drug that inhibits the catalytic activity of topoisomerase II (topo II) without damaging DNA or stabilizing DNA-topo II cleavable complexes (IC50 = 20 μM for purified mammalian topo II versus IC50 = ~ 200 μM for topo I). Also induces apoptosis in human leukemic CEM cells through a caspase-3-like protease-dependent mechanism.
Biochem/physiol Actions
Cell permeable: yes
MERBARONE Preparation Products And Raw materials
Raw materials
Preparation Products
MERBARONE Suppliers
Global( 36)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2127 | 70 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Chunchuang (Wuhan) Technology Co., Ltd | 15342225168 | yutianchun2007@126.com | China | 10355 | 58 |
| Shanghai Naiys Biological Technology Co., Ltd | 18321139117 | 316441092@qq.con | China | 3005 | 58 |
| Changzhou Bojia Biomedical Technology Co., Ltd. | 2122619822 | czbjpharma@126.com | China | 18488 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
| Shanghai Tachizaki Biomedical Research Center | 18014399201 | sales@chemlab-tachizaki.com | China | 2488 | 58 |
| Jinan Sanbao Biotechnology Co., Ltd. | 13854185395; 13854185395 | sanbaobiotech@126.com | China | 8261 | 58 |
97534-21-9(MERBARONE)Related Search:
5-(N-PHENYLCARBAMOYL)-2-THIOBARBITURIC ACID
5-(N-PHENYLCARBOXAMIDO)-2-THIOBARBITURIC ACID
NSC-336628
hexahydro-4,6-dioxo-n-phenyl-2-thioxo-5-pyrimidinecarboxamid
5-(N-Phenylcarbamoyl)-2-thiobarbituric acid, NSC-336628
MERBARONE
4,6-dioxo-N-phenyl-2-sulfanylidene-1,3-diazinane-5-carboxamide
Merbarone - CAS 97534-21-9 - Calbiochem
5-Pyrimidinecarboxamide, hexahydro-4,6-dioxo-N-phenyl-2-thioxo-
RLBN1001
RLBN-1001
97534-21-9
Reagents
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