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SECO RAPAMYCIN SODIUM SALT

CAS No.
148554-65-8
Chemical Name:
SECO RAPAMYCIN SODIUM SALT
Synonyms
Secosirolimus;Secorapamycin Na salt;SECORAPAMYCIN A MONOSODIUM;SECO RAPAMYCIN SODIUM SALT;seco Rapamycin Sodium Salt, >85% By HPLC;(19E/Z)-seco Rapamycin Sodium Salt, (>80% HPLC);(19E/Z)-seco Rapamycin Sodium Salt (~80% by HPLC)
CBNumber:
CB4501000
Molecular Formula:
C51H80NNaO13
Molecular Weight:
938.18
MDL Number:
MOL File:
148554-65-8.mol
Last updated:2023-05-18 11:31:00

SECO RAPAMYCIN SODIUM SALT Properties

Melting point 120-122°C
storage temp. Amber Vial, -20°C Freezer, Under Inert Atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color Pale Yellow to Yellow
Stability Light Sensitive

SECO RAPAMYCIN SODIUM SALT price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 16158 Seco Rapamycin (sodium salt) ≥85% 148554-65-8 1mg $118 2024-03-01 Buy
Cayman Chemical 16158 Seco Rapamycin (sodium salt) ≥85% 148554-65-8 10mg $701 2024-03-01 Buy
Cayman Chemical 16158 Seco Rapamycin (sodium salt) ≥85% 148554-65-8 500μg $65 2021-12-16 Buy
Cayman Chemical 16158 Seco Rapamycin (sodium salt) ≥85% 148554-65-8 5mg $468 2024-03-01 Buy
TRC R124010 (19E/Z)-secoRapamycinSodiumSalt(~80%byHPLC) 148554-65-8 10mg $205 2021-12-16 Buy
Product number Packaging Price Buy
16158 1mg $118 Buy
16158 10mg $701 Buy
16158 500μg $65 Buy
16158 5mg $468 Buy
R124010 10mg $205 Buy

SECO RAPAMYCIN SODIUM SALT Chemical Properties,Uses,Production

Description

Rapamycin is a natural macrolide immunosuppressant that activates mTORC1. Seco Rapamycin (sodium salt) is a nonenzyme-dependent degradation product of rapamycin resulting from ester hydration followed by dehydration. It has less than 4% of the potency of rapamycin in a thymocyte proliferation assay. Rapamycin quickly degrades to two ring-opened products, including seco rapamycin, in the cytoplasm or in homogenates of Caco-2 cells. Like rapamycin, seco rapamycin is secreted from cells by P-glycoprotein and metabolized to a common dihydro species. While seco rapamycin poorly activates mTOR, it mimics rapamycin in its ability to inhibit the proteasome.

Chemical Properties

Yellow Solid

Uses

A metabolite of Sirolimus

Uses

A decomposition product of Rapamycin (R124000).

SECO RAPAMYCIN SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

SECO RAPAMYCIN SODIUM SALT Suppliers

Global( 46)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5700 66
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4863 58
Shenzhen SUNGENING Bio-Medical Co., Ltd. 0755-28967200 13631290199 wxf@sungening.com China 9506 60
Musechem +1-800-259-7612 info@musechem.com United States 4662 60
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9414 58
Hefei fuya biotechnology co. LTD 18096409024 sales02@foreversyn.com China 1935 58

148554-65-8(SECO RAPAMYCIN SODIUM SALT)Related Search:

seco Rapamycin Sodium Salt, >85% By HPLC SECO RAPAMYCIN SODIUM SALT SECORAPAMYCIN A MONOSODIUM (19E/Z)-seco Rapamycin Sodium Salt (~80% by HPLC) (19E/Z)-seco Rapamycin Sodium Salt, (>80% HPLC) Secorapamycin Na salt Secosirolimus 148554-65-8 C51H78NNaO13 Metabolites & Impurities Various Metabolites and Impurities Chiral Reagents Heterocycles Impurities Intermediates & Fine Chemicals Pharmaceuticals