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(R)-BAY1238097

(R)-BAY1238097 Structure
(R)-BAY1238097 structure
CAS No.
1564269-85-7
Chemical Name:
(R)-BAY1238097
Synonyms
(R)-BAY1238097;(R)BAY1238097,(R) BAY1238097,(R)-BAY-1238097;3H-2,3-Benzodiazepine-3-carboxamide, 4,5-dihydro-7,8-dimethoxy-N,4-dimethyl-1-[4-(4-methyl-1-piperazinyl)phenyl]-, (4R)-
CBNumber:
CB45419641
Molecular Formula:
C25H33N5O3
Molecular Weight:
451.56
MDL Number:
MOL File:
1564269-85-7.mol
Last updated:2023-05-21 10:59:17
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(R)-BAY1238097 Properties

Density 1.22±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 150 mg/mL (332.18 mM);Water : < 0.1 mg/mL (insoluble)
pka 15.43±0.60(Predicted)

(R)-BAY1238097 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0089882 (R)-BAY1238097 99.61% 1564269-85-7 5mg $250 2021-12-16 Buy
ChemScene CS-0089882 (R)-BAY1238097 99.61% 1564269-85-7 10mg $390 2021-12-16 Buy
ChemScene CS-0089882 (R)-BAY1238097 99.61% 1564269-85-7 50mg $1250 2021-12-16 Buy
ChemScene CS-0089882 (R)-BAY1238097 99.61% 1564269-85-7 100mg $2100 2021-12-16 Buy
Product number Packaging Price Buy
CS-0089882 5mg $250 Buy
CS-0089882 10mg $390 Buy
CS-0089882 50mg $1250 Buy
CS-0089882 100mg $2100 Buy

(R)-BAY1238097 Chemical Properties,Uses,Production

Description

(R)-BAY1238097 is the R-isomer with lower activity of BAY1238097. BAY1238097 is a potent and selective inhibitor of BET binding to histones and has strong anti-proliferative activity in different AML (acute myeloid leukemia) and MM (multiple myeloma) models through down-regulation of c-Myc levels and its downstream transcriptome[1][2]. BET[1].

References

[1]. Lejeune, P., et al. (2015) Abstract 3524: BAY 1238097, a novel BET inhibitor with strong efficacy in hematological tumor models. Cancer Research, 75(15 Suppl), 884. [2]. Bernasconi E, et al. Preclinical evaluation of the BET bromodomain inhibitor BAY 1238097 for the treatment of lymphoma. Br J Haematol. 2017 Sep;178(6):936-948.

(R)-BAY1238097 Preparation Products And Raw materials

Raw materials

Preparation Products

(R)-BAY1238097 Suppliers

Global( 12)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088 3193328036@qq.com China 29795 68
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9730 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5132 58
InvivoChem 13549236410 sales@invivochem.cn China 6749 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9180 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
InvivoChem 		58
Aladdin Scientific 		58
Beijing Solarbio Science & Tecnology Co., Ltd. 68
Fan De(Beijing) Biotechnology Co., Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai hongqu biomedical technology co. LTD 58
InvivoChem 58
TargetMol Chemicals Inc. 58
RD International Technology Co., Limited 58
(R)-BAY1238097 3H-2,3-Benzodiazepine-3-carboxamide, 4,5-dihydro-7,8-dimethoxy-N,4-dimethyl-1-[4-(4-methyl-1-piperazinyl)phenyl]-, (4R)- (R)BAY1238097,(R) BAY1238097,(R)-BAY-1238097 1564269-85-7