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SGK1 Inhibitor

CAS No.
1426214-51-8
Chemical Name:
SGK1 Inhibitor
Synonyms
N-[4-(3-amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,3-dichloro-benzenesulfonamide;Benzenesulfonamide, N-[4-(3-amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,3-dichloro-
CBNumber:
CB45540787
Molecular Formula:
C17H12Cl2N6O2S
Molecular Weight:
435.29
MDL Number:
MOL File:
1426214-51-8.mol
Last updated:2023-04-23 13:52:06

SGK1 Inhibitor Properties

Boiling point 730.5±70.0 °C(Predicted)
Density 1.660±0.06 g/cm3(Predicted)
solubility DMSO: soluble
form A solid
pka 5.86±0.10(Predicted)

SGK1 Inhibitor price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 25652 SGK1 Inhibitor 1426214-51-8 1mg $37 2024-03-01 Buy
Cayman Chemical 25652 SGK1 Inhibitor 1426214-51-8 25mg $704 2024-03-01 Buy
Cayman Chemical 25652 SGK1 Inhibitor 1426214-51-8 5mg $169 2024-03-01 Buy
Cayman Chemical 25652 SGK1 Inhibitor 1426214-51-8 10mg $319 2024-03-01 Buy
AK Scientific 9244DU N-[4-(3-Amino-2H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,3-dichlorobenzenesulfonamide 1426214-51-8 10mg $452 2021-12-16 Buy
Product number Packaging Price Buy
25652 1mg $37 Buy
25652 25mg $704 Buy
25652 5mg $169 Buy
25652 10mg $319 Buy
9244DU 10mg $452 Buy

SGK1 Inhibitor Chemical Properties,Uses,Production

Description

SGK1 inhibitor is an inhibitor of serum- and glucocorticoid-regulated kinase 1 (SGK1) and SGK2. It is selective for SGK1 and SGK2 over SGK3 in the presence of a high concentration of ATP. SGK1 inhibitor prevents phosphorylation of GSK3β in U2OS cells and decreases cell viability in BYL719-insensitive HCC1954 cells when used in combination with the PI3Kα inhibitor BYL719. SGK1 inhibitor reduces tumor growth in an HCC1954 mouse xenograft model when administered in combination with BYL719.

SGK1 Inhibitor Preparation Products And Raw materials

Raw materials

Preparation Products

SGK1 Inhibitor Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1249 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Benzenesulfonamide, N-[4-(3-amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,3-dichloro- N-[4-(3-amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,3-dichloro-benzenesulfonamide 1426214-51-8