(E,E)-Farnesol
- CAS No.
- 106-28-5
- Chemical Name:
- (E,E)-Farnesol
- Synonyms
- trans-Farnesol;(2E,6E)-Farnesol;TRANS,TRANS-FARNESOL;(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol;FEMA 2478;3,7,11-TRIMETHYLDODECA-2,6,10-TRIEN-1-OL;Inhibitor A2;(E)-farnesol;(E,E)-FARNESOL;all-E-Farnesol
- CBNumber:
- CB4669245
- Molecular Formula:
- C15H26O
- Molecular Weight:
- 222.37
- MDL Number:
- MFCD00002918
- MOL File:
- 106-28-5.mol
- MSDS File:
- SDS
| Melting point | 61-63 °C |
|---|---|
| Boiling point | 149 °C4 mm Hg(lit.) |
| Density | 0.886 g/mL at 20 °C(lit.) |
| refractive index |
n |
| Flash point | 205 °F |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Sparingly), DMSO (Slightly) Ethyl Acetate (Slightly) |
| pka | 14.42±0.10(Predicted) |
| color | Colourless |
| Odor | at 100.00 %. mild muguet floral sweet lily waxy |
| Odor Type | floral |
| Water Solubility | Miscible with alcohol. Immiscible with water. |
| Sensitive | Light Sensitive |
| BRN | 1723039 |
| Stability | Light Sensitive |
| InChIKey | CRDAMVZIKSXKFV-YFVJMOTDSA-N |
| LogP | 5.31 |
| CAS DataBase Reference | 106-28-5(CAS DataBase Reference) |
| FDA UNII | X23PI60R17 |
| NIST Chemistry Reference | 2,6,10-Dodecatrien-1-ol, 3,7,11-trimethyl-, (E,E)-(106-28-5) |
| EPA Substance Registry System | (E,E)-Farnesol (106-28-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317 | |||||||||
| Precautionary statements | P261-P272-P280-P302+P352-P333+P313-P362+P364 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 43 | |||||||||
| Safety Statements | 24/25-36/37 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | JR4979000 | |||||||||
| F | 8 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29052290 | |||||||||
| NFPA 704 |
|
(E,E)-Farnesol price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 277541 | trans,trans-Farnesol 96% | 106-28-5 | 1g | $40.6 | 2024-03-01 | Buy |
| Sigma-Aldrich | 277541 | trans,trans-Farnesol 96% | 106-28-5 | 10g | $216 | 2024-03-01 | Buy |
| Alfa Aesar | L14348 | trans,trans-Farnesol 97% | 106-28-5 | 1g | $22.65 | 2024-03-01 | Buy |
| Alfa Aesar | L14348 | trans,trans-Farnesol 97% | 106-28-5 | 5g | $103 | 2024-03-01 | Buy |
| Sigma-Aldrich | 92386 | trans,trans-Farnesol AldrichCPR | 106-28-5 | 100mg | $88.3 | 2022-05-15 | Buy |
(E,E)-Farnesol Chemical Properties,Uses,Production
Description
Farnesol is widely present in the flowers, leaves, stems and other parts of plants, especially in some Chinese herbal medicine plants and spice plants with a high content, such as Cinnamomum chinensis, Pinellia sinensis, loquat leaves, etc., which are well developed and utilized An important resource for prospects. Farnesol is one of the important active components of Chinese herbal medicine plants, and also one of the main fragrance components of some important essential oils of spice plants. Therefore, it has been widely used in medicine, pesticides, cosmetics and daily chemicals that require its biological activity.
Chemical Properties
Clear Colourless Oil
Uses
trans,trans-Farnesol is an intermediate used in the biological synthesis of cholesterol from mevalonic acid. It is used in the perfume industry. Further, it is used in the preparation of terpenes such as squalenes, cembranoids and forskolin. It is also used in the synthesis of Cecropia juvenile hormone.
Uses
Farnesol is a natural organic compound which is present in many essential oils.
Definition
ChEBI: Farnesol is a farnesane sesquiterpenoid that is dodeca-2,6,10-triene substituted by methyl groups at positions 3, 7 and 11 and a hydroxy group at position 1. It has a role as a plant metabolite, a fungal metabolite and an antimicrobial agent. It is a farnesane sesquiterpenoid, a primary alcohol and a polyprenol.
Synthesis Reference(s)
Journal of the American Chemical Society, 102, p. 3298, 1980 DOI: 10.1021/ja00529a091
The Journal of Organic Chemistry, 40, p. 3617, 1975 DOI: 10.1021/jo00912a039
General Description
trans,trans-Farnesol is sesquiterpene alcohol, which is commonly found in many essential oils, citrus fruits, propolis, and plant-derived foods and beverages. It is an effective bioactive agent that can be used in pharmaceuticals and cosmetics.
Purification Methods
The main impurity is the cis-trans isomer. Purify it by gas chromatography using a 4ft x 0.125in 3%OV-1 column at 150o. [Corey et al. J Am Chem Soc 92 6637 1970, Popjak et al. J Biol Chem 237 56 1962.] It has also been fractionated through a 14-in Podbielniak column (p 11) at 11o/0.35mm. Alternatively it has been purified by gas chromatography using SF96 silicone on Fluoropak columns or Carbowax 20M on Fluoropak or base-washed 30:60 firebrick (to avoid decomposition, prepared by treating the firebrick with 5N NaOH in MeOH and washed with MeOH to pH 8) at 210o with Helium carrier gas at 60 mL/min flow rate. The diphenylcarbamoyl derivative has m 61-63o (from MeOH) and has an IR band at 3500 cm-1. [Bates et al. J Org Chem 28 1086 1963, Beilstein 1 IV 2335.]
(E,E)-Farnesol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
| Hebei Kangcang new material Technology Co., LTD | +8619133911216 | Jany1001@kangcang.com.cn | China | 338 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15371 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9352 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
View Lastest Price from (E,E)-Farnesol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-19 | (2E,6E)-Farnesol
106-28-5
|
US $9.00-70.00 / g | 10g | 99% | 10 tons | Hebei Kangcang new material Technology Co., LTD | |
 |
2023-12-20 | (E,E)-Farnesol
106-28-5
|
US $0.00-0.00 / kg | 1kg | 0.99 | 50000kg | Hebei Yibangte Import and Export Co. , Ltd. | |
 |
2023-09-06 | (E,E)-Farnesol
106-28-5
|
US $0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. |
-
- (2E,6E)-Farnesol
106-28-5
- US $9.00-70.00 / g
- 99%
- Hebei Kangcang new material Technology Co., LTD
-
- (E,E)-Farnesol
106-28-5
- US $0.00-0.00 / kg
- 0.99
- Hebei Yibangte Import and Export Co. , Ltd.
-
- (E,E)-Farnesol
106-28-5
- US $0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.