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SB 221284

CAS No.
196965-14-7
Chemical Name:
SB 221284
Synonyms
SB 221284;5-(METHYLTHIO)-1-(3-PYRIDYLCARBAMOYL)-6-(TRIFLUOROMETHYL)INDOLINE;2,3-DIHYDRO-5-(METHYLTHIO)-N-3-PYRIDINYL-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE;1H-Indole-1-carboxamide, 2,3-dihydro-5-(methylthio)-N-3-pyridinyl-6-(trifluoromethyl)-
CBNumber:
CB4704933
Molecular Formula:
C16H14F3N3OS
Molecular Weight:
353.36
MDL Number:
MOL File:
196965-14-7.mol
Last updated:2023-07-14 17:47:10

SB 221284 Properties

Melting point 262-264 °C
Boiling point 536.2±50.0 °C(Predicted)
Density 1.43±0.1 g/cm3(Predicted)
storage temp. Store at +4°C
solubility DMSO: ~14 mg/mL, soluble
form solid
pka 13.13±0.20(Predicted)
color white

SAFETY

Risk and Safety Statements

WGK Germany  3

SB 221284 price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 1379 SB221284 ≥99%(HPLC) 196965-14-7 10 $96 2021-12-16 Buy
Tocris 1379 SB221284 ≥99%(HPLC) 196965-14-7 50 $400 2021-12-16 Buy
TRC S155028 SB221284 196965-14-7 5mg $170 2021-12-16 Buy
American Custom Chemicals Corporation BRS0000723 SB 221284 95.00% 196965-14-7 10MG $709.46 2021-12-16 Buy
ApexBio Technology B6713 SB221284 196965-14-7 50mg $786 2021-12-16 Buy
Product number Packaging Price Buy
1379 10 $96 Buy
1379 50 $400 Buy
S155028 5mg $170 Buy
BRS0000723 10MG $709.46 Buy
B6713 50mg $786 Buy

SB 221284 Chemical Properties,Uses,Production

Uses

SB 221284 is a potent, selective SR-2C/SR-2B antagonist.

Definition

ChEBI: SB 221284 is an indolyl carboxylic acid.

Biological Activity

Potent, selective 5-HT 2C/2B receptor antagonist. pK i values are 6.4, 7.9 and 8.6 for 5-HT 2A , 2B and 2C receptors respectively. Centrally active upon systemic administration in vivo .

SB 221284 Preparation Products And Raw materials

Raw materials

Preparation Products

SB 221284 Suppliers

Global( 32)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
BOC Sciences -- info@bocsci.com USA 0 65
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44894 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 4028 58
ApexBio Technology -- sales@apexbt.com United States 6254 58
5-(METHYLTHIO)-1-(3-PYRIDYLCARBAMOYL)-6-(TRIFLUOROMETHYL)INDOLINE 2,3-DIHYDRO-5-(METHYLTHIO)-N-3-PYRIDINYL-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE SB 221284 1H-Indole-1-carboxamide, 2,3-dihydro-5-(methylthio)-N-3-pyridinyl-6-(trifluoromethyl)- 196965-14-7 C16H14N3F3OS