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Nalpha-FMOC-L-Glutamine

Nalpha-FMOC-L-Glutamine structure

CAS No.: 71989-20-3

Chemical Name:: Nalpha-FMOC-L-Glutamine

Synonyms: FMOC-GLN;NSC334303;FMOC-L-GLN;FMOC-GLN-OH;Fmoc-GIn-OH;Fmoc-Gln-0H;FMOC-L-GLN-OH;FMOC-GLUTAMINE;FMOC-L-GLUTAMINE;Fmoc-Glutamine-OH

CBNumber:: CB4714259

Molecular Formula:: C20H20N2O5

Molecular Weight:: 368.38

MDL Number:: MFCD00037137

MOL File:: 71989-20-3.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:54

Product description	Number	Pack Size	Price
Fmoc-Gln-OH Novabiochem?	8.52205	5G	$27.2
Fmoc-Gln-OH Novabiochem?	8.52205	25g	$72.6
Fmoc-Gln-OH Novabiochem?	8.52205	100g	$224
Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamine >98.0%(HPLC)	F0308	1g	$19
Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamine >98.0%(HPLC)	F0308	5g	$46
More product size

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Nalpha-FMOC-L-Glutamine Properties

Melting point	220 °C (dec.)(lit.)
alpha	-18 º (c=1,DMF)
Boiling point	498.73°C (rough estimate)
Density	1.3116 (rough estimate)
refractive index	-18 ° (C=1, DMF)
storage temp.	2-8°C
solubility	almost transparency in N,N-DMF
form	powder to crystal
pka	3.73±0.10(Predicted)
color	White to Almost white
optical activity	[α]20/D 18.5±1.5°, c = 1% in DMF
BRN	4722773
CAS DataBase Reference	71989-20-3(CAS DataBase Reference)
UNSPSC Code	12352209
NACRES	NA.26

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Hazard Codes

Risk Statements

36/37/38

Safety Statements

24/25-36/37/39-27-26

WGK Germany

HazardClass

IRRITANT

HS Code

29242990

NFPA 704

	0
1		0

Nalpha-FMOC-L-Glutamine price More Price(51)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	8.52205	Fmoc-Gln-OH Novabiochem?	71989-20-3	5G	$27.2	2025-07-31	Buy
Sigma-Aldrich	8.52205	Fmoc-Gln-OH Novabiochem?	71989-20-3	25g	$72.6	2025-07-31	Buy
Sigma-Aldrich	8.52205	Fmoc-Gln-OH Novabiochem?	71989-20-3	100g	$224	2025-07-31	Buy
TCI Chemical	F0308	Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamine >98.0%(HPLC)	71989-20-3	1g	$19	2025-07-31	Buy
TCI Chemical	F0308	Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamine >98.0%(HPLC)	71989-20-3	5g	$46	2025-07-31	Buy

Product number	Packaging	Price	Buy
8.52205	5G	$27.2	Buy
8.52205	25g	$72.6	Buy
8.52205	100g	$224	Buy
F0308	1g	$19	Buy
F0308	5g	$46	Buy

Nalpha-FMOC-L-Glutamine Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

N2-Fmoc-L-glutamine is an N-Fmoc-protected form of L-Glutamine (G597000). L-Glutamine is a non-essential amino acid that is important for cells that proliferate quickly in the body, such as those of the immune system. L-Glutamine is known to be especially important for the gut, as it helps to maintain intestinal structure and function. L-Glutamine also has protective properties against host toxicity of chemotherapy in cancer patients.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

Synthesis

56-85-9

N-(9-Fluorenylmethoxycarbonyloxy)succinimide

82911-69-1

71989-20-3

To a stirred solution of L-glutamine (1.75 g, 12 mmol) and sodium carbonate (1.27 g, 12 mmol) in 30 mL of water, a solution of 9-fluorenylmethyl-N-succinimidyl carbonate (Fmoc-OSu, 3.0 g, 8.9 mmol) dissolved in 60 mL of tetrahydrofuran (THF) was slowly added. The reaction mixture was stirred overnight at room temperature. Subsequently, THF was removed by distillation under reduced pressure. the residue was diluted with 100 mL of 1N hydrochloric acid and the precipitated white solid was collected by filtration. The solid was further recrystallized in a mixed aqueous solution of DMF with 0.1 N hydrochloric acid to afford the target product (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-amino-5-oxopentanoic acid as a white powder (2.76 g, 84% yield). The product was characterized by 1H-NMR (90 MHz, DMSO-d6) with chemical shifts of 12.47 (1H, s), 7.89-7.20 (10H, m), 6.68 (1H, s, br), 4.22-3.90 (4H, m), and 2.25-1.86 (4H, m).

References

[1] Journal of Peptide Science, 2017, vol. 23, # 3, p. 202 - 214
[2] Patent: US2006/161007, 2006, A1. Location in patent: Page/Page column 12
[3] Synthetic Communications, 2009, vol. 39, # 11, p. 2022 - 2031

Nalpha-FMOC-L-Glutamine synthesis

Synthesis of Nalpha-FMOC-L-Glutamine from L-Glutamine and Fmoc-OSu

Nalpha-FMOC-L-Glutamine Preparation Products And Raw materials

Raw materials

L-Glutamine Fmoc-OSu Sodium carbonate Tetrahydrofuran Water

Preparation Products

MELITTIN

Nalpha-FMOC-L-Glutamine Suppliers

Global( 406)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd	+8617390183901	cynthia@enlaibio.com	China	1100	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21616	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29850	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2954	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6369	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Sichuan Jiaying Lai Technology Co.,LTD	18716376478	ycling@enlaibio.com	CHINA	302	58

Supplier	Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Jinan Finer Chemical Co., Ltd	58
Accela ChemBio Inc.	58
Xiamen AmoyChem Co., Ltd	58
Hubei xin bonus chemical co. LTD	58
Sichuan Jiaying Lai Technology Co.,LTD	58

View Lastest Price from Nalpha-FMOC-L-Glutamine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-07	Fmoc-L-Gln-OH 71989-20-3	US $0.00-0.00 / kg	1kg	98%	1T	Sichuan HongRi Pharma-Tech Co.,Ltd
2025-11-07	N-Fmoc-L-Glutamine 71989-20-3	US $5.00 / kg	1kg	≥99%	100mt/year	Jinan Finer Chemical Co., Ltd
2025-11-06	Nalpha-FMOC-L-Glutamine 71989-20-3	US $0.00 / kg	1kg	98%min	500kg	WUHAN FORTUNA CHEMICAL CO., LTD

Fmoc-L-Gln-OH
71989-20-3
US $0.00-0.00 / kg
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

N-Fmoc-L-Glutamine
71989-20-3
US $5.00 / kg
≥99%
Jinan Finer Chemical Co., Ltd

Nalpha-FMOC-L-Glutamine
71989-20-3
US $0.00 / kg
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

Nalpha-FMOC-L-Glutamine Spectrum

Nalpha-FMOC-L-Glutamine(71989-20-3)MS Nalpha-FMOC-L-Glutamine(71989-20-3)¹HNMR Nalpha-FMOC-L-Glutamine(71989-20-3)¹³CNMR Nalpha-FMOC-L-Glutamine(71989-20-3)IR1 Nalpha-FMOC-L-Glutamine(71989-20-3)IR2

71989-20-3(Nalpha-FMOC-L-Glutamine)Related Search:

Transglutaminase 9-Fluorenylmethyl chloroformate Boc-D-Glutamine L-Alanyl-L-Glutamine L-Glutamine

Glycyl-L-glutamine monohydrate Fmoc-Aib-OH Fmoc-OSu Fmoc-L-aspartic acid Fmoc-D-Asn(Trt)-OH

FMOC-5-AMINOPENTANOIC ACID Fmoc-Gly-OH Fmoc-D-phenylalanine Fmoc-Met-OH FMOC-L-Methionine

Fmoc-D-leucine Fmoc-D-tryptophan Fmoc-D-Tyr(tBu)-OH

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N-(9-FLUORENYLMETHOXYCARBONYL)-L-GLUTAMINE N-ALPHA-FMOC-L-GLUTAMINE N-ALPHA-FMOC-L-GLN 9-FLUORENYLMETHOXYCARBONYL-L-GLUTAMINE n(alpha)-fluorenylmethoxycarbonylglutamine NSC334303 L-GLUTAMINE-N-FMOC (13C5,15N2) Fmoc-L-glutamine≥ 99% (HPLC, Chiral purity) N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-glutamine N-α-Fmoc-L-glutamine NA-FMOC-L-GLUTAMINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-& L-Glutamine-UL-13C5,UL-15N2-N-FMOC FMOC-L-GLUTAMINE extrapure 5-Amino-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxopentanoic acid N2-(9H-Fluorene-9-ylmethoxycarbonyl)-L-glutamine Nα-(9H-Fluorene-9-ylmethoxycarbonyl)-L-glutamine Nalpha-FMOC-L-Glutamine,98% N-(9-Fluorenylmethyloxycarbonyl)-L-glutamine ,98% Nalpha-FMOC-L-Glutam Fmoc-Glutamine-OH L-GLUTAMINE-N-FMOC (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-5-amino-5-oxopentanoic acid Nalpha-Fmoc-L-glutamine Fmoc-Gln-OH 4-Carbamoyl-2-([(9H-fluoren-9-ylmethoxy)carbonyl]amino)butanoic acid 5-amino-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-keto-valeric acid 5-amino-2-[(9H-fluoren-9-ylmethoxy-oxomethyl)amino]-5-oxopentanoic acid FMOC-L-GLUTAMINE FMOC-L-GLN-OH FMOC-L-GLN FMOC-GLN-OH FMOC-GLN FMOC-GLUTAMINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-GLUTAMINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-GLUTAMINE NALPHA-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-GLUTAMINE N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-GLUTAMINE N-9-FLUORENYLMETHYLOXYCARBONYL-L-GLUTAMINE (9H-Fluoren-9-yl)MethOxy]Carbonyl Gln-OH (2S)-4-carbamoyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamine> L-Glutamine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]- Nalpha-FMOC-L-Glutamine USP/EP/BP Fmoc-L-glutamine, puriss, 99% TIANFU-CHEM Nalpha-FMOC-L-Glutamine Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamine (2S)-5-amino-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxopentanoic acid Fmoc-GIn-OH Fmoc-Gln-0H Na-(9-Fluorenylmethoxycarbonyl)-L-glutamine Nα-Fmoc-L-glutamine 71989-20-3 7198-20-3 71686-20-3 C20H20N2O5 H2NCOCH22CHNHFMOCCOOH C20H19N2O5 Glutamine