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1-Hydroxyethylidene-1,1-diphosphonic acid

1-Hydroxyethylidene-1,1-diphosphonic acid
1-Hydroxyethylidene-1,1-diphosphonic acid
CAS No.
2809-21-4
Chemical Name:
1-Hydroxyethylidene-1,1-diphosphonic acid
Synonyms
ehdp;HEDP;HEDPA;HDEPA;OEDFK;1000sl;turpinalsl;dequest2015;dequestz010;ferrofos510
CBNumber:
CB4719658
Molecular Formula:
C2H8O7P2
Formula Weight:
206.03
MOL File:
2809-21-4.mol

1-Hydroxyethylidene-1,1-diphosphonic acid Properties

Melting point:
198~199℃
Density 
1.45 (60% aq.)
pka
1.35, 2.87, 7.03, 11.3(at 25℃)
form 
Powder
color 
white
Water Solubility 
Soluble in water.
Merck 
14,3863
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
DBVJJBKOTRCVKF-UHFFFAOYSA-N
CAS DataBase Reference
2809-21-4(CAS DataBase Reference)
EPA Substance Registry System
Phosphonic acid, (1-hydroxyethylidene)bis-(2809-21-4)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi,Xn
Risk Statements  37/38-41-22
Safety Statements  26-39
RIDADR  UN 3265
WGK Germany  2
RTECS  SZ8562100
10
TSCA  Yes
HazardClass  8
PackingGroup  II
HS Code  29319090
Hazardous Substances Data 2809-21-4(Hazardous Substances Data)
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H290 May be corrosive to metals Corrosive to Metals Category 1 Warning P234, P390, P404
H303 May be harmfulif swallowed Acute toxicity,oral Category 5 P312
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
Precautionary statements:
P234 Keep only in original container.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P390 Absorb spillage to prevent material damage.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
P406 Store in corrosive resistant/… container with a resistant inner liner.
P501 Dispose of contents/container to..…

1-Hydroxyethylidene-1,1-diphosphonic acid price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H6773 Etidronic acid 60% aqueous solution 2809-21-4 100g $48.6 2018-11-13 Buy
Sigma-Aldrich H6773 Etidronic acid 60% aqueous solution 2809-21-4 500g $192 2018-11-13 Buy
TCI Chemical H0587 1-Hydroxyethane-1,1-diphosphonic Acid (ca. 60% in Water, ca. 4.2mol/L) 2809-21-4 25g $24 2018-11-22 Buy
TCI Chemical H0587 1-Hydroxyethane-1,1-diphosphonic Acid (ca. 60% in Water, ca. 4.2mol/L) 2809-21-4 500g $93 2018-11-22 Buy
Alfa Aesar 043502 1-Hydroxyethylidenebis(phosphonic acid), 96% 2809-21-4 10g $101 2018-11-16 Buy

1-Hydroxyethylidene-1,1-diphosphonic acid Chemical Properties,Uses,Production

Chemical Properties

light beige powder

Uses

Etidronate (Didronel) is a human protein tyrosine phosphatase inhibitor with IC50 of 0.2 μM.

Definition

ChEBI: A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.

brand name

Didronel (Millot Laboratories, France); Didronel (Procter & Gamble).

1-Hydroxyethylidene-1,1-diphosphonic acid Preparation Products And Raw materials

Raw materials

Preparation Products


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