Diloxanide furoate
- CAS No.
- 3736-81-0
- Chemical Name:
- Diloxanide furoate
- Synonyms
- 8073cb;Furoate;furamide;amebiazol;furentomin;histomibal;diclofurazol;dichlofurazol;entamidefuroate;diloxanidfuroate
- CBNumber:
- CB4723149
- Molecular Formula:
- C14H11Cl2NO4
- Molecular Weight:
- 328.15
- MDL Number:
- MFCD00083302
- MOL File:
- 3736-81-0.mol
- MSDS File:
- SDS
| Melting point | 111-114 °C |
|---|---|
| Boiling point | 438.4±45.0 °C(Predicted) |
| Density | 1.424±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | -0?+-.0.50(Predicted) |
| color | Off-White to Light Beige |
| BCS Class | 4 |
| CAS DataBase Reference | 3736-81-0(CAS DataBase Reference) |
| FDA UNII | YP4N72IW34 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P301+P312+P330 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 36 |
| WGK Germany | 3 |
| RTECS | LV1821800 |
| HS Code | 2924296000 |
| Toxicity | mouse,LDLo,oral,710mg/kg (710mg/kg),Archives of Environmental Contamination and Toxicology. Vol. 14, Pg. 111, 1985. |
Diloxanide furoate price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1204805 | Diloxanide furoate United States Pharmacopeia (USP) Reference Standard | 3736-81-0 | 200mg | $381 | 2024-03-01 | Buy |
| TRC | F861000 | Furamide | 3736-81-0 | 500mg | $430 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD63298 | Diloxanide furoate | 3736-81-0 | 250mg | $450 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0002378 | DILOXANIDE FUROATE 95.00% | 3736-81-0 | 1G | $1428 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0002378 | DILOXANIDE FUROATE 95.00% | 3736-81-0 | 1KG | $6706.51 | 2021-12-16 | Buy |
Diloxanide furoate Chemical Properties,Uses,Production
Uses
Furamide is an ambecide, an anti-protozoal drug used in the treatment of amoebozoa infections.
Uses
Antidiarrhoeals / Antiprotozoles
Uses
selective agonist for delta-opioid receptor
Definition
ChEBI: Diloxanide furoate is a carboxylic ester resulting from the formal condensation of the carboxy group of furan-2-carboxylic acid with the hydroxy group of 2,2-dichloro-N-(4-hydroxyphenyl)-N-methylacetamide. It is a drug used for the treatment of asymptomatic amebiasis. It has a role as an antiamoebic agent and a prodrug. It is a member of furans, a carboxylic ester, a tertiary carboxamide and an organochlorine compound.
Indications
Diloxanide furoate (Furamide) is an amebicide that is effective against trophozoites in the intestinal tract. In mild or asymptomatic infections, cures of 83 to 95% have been achieved; in patients with dysentery, cure rates may be less impressive. The drug is administered only orally and is rapidly absorbed from the gastrointestinal tract following hydrolysis of the ester group. It is remarkably free of side effects, but occasionally flatulence, abdominal distention, anorexia, nausea, vomiting, diarrhea, pruritus, and urticaria occur. Diloxanide is excreted in the urine, largely as the glucuronide. It is not available in the United States.
Clinical Use
Diloxanide furoate (available from the Centers for Disease Control and Prevention [CDC]) is prescribed for the treatment of asymptomatic amebiasis but is ineffective as a single agent for the extraintestinal form of the disease. The drug is administered orally and is hydrolyzed in the gut to give diloxanide, which is considered to be the active drug. Diloxanide is the only form identified in the bloodstream. The drug is found in the urine as the glucuronide.
Diloxanide furoate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 | 1015@dideu.com | China | 2263 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | peter68@ptchemgroup.com | China | 35453 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 20000 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
View Lastest Price from Diloxanide furoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-04-28 | Diloxanide furoate
3736-81-0
|
US $0.00-0.00 / Kg | 1KG | 99.0% | 500 tons | Shaanxi Dideu Medichem Co. Ltd |
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- Diloxanide furoate
3736-81-0
- US $0.00-0.00 / Kg
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd