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S-ADENOSYL-L-METHIONINE CHLORIDE SALT

S-ADENOSYL-L-METHIONINE CHLORIDE SALT structure

CAS No.: 24346-00-7

Chemical Name:: S-ADENOSYL-L-METHIONINE CHLORIDE SALT

Synonyms: SAM-Cl;SAM CHLORIDE;Einecs 246-184-8;ACTIVE METHIONINE;SAM-E CHLORIDE SALT;ADEMETHIONINECHLORIDE;Active methionine chloride;S-ADENOSYL-L-METHIONINE CHLORIDE;ADENOSYL-L-METHIONINE CHLORIDE, S-;S-ADENOSYL METHIONINE CHLORIDE SALT

CBNumber:: CB4723189

Molecular Formula:: C15H23ClN6O5S

Molecular Weight:: 434.9

MDL Number:: MFCD00036337

MOL File:: 24346-00-7.mol

MSDS File:: SDS

Last updated:2023-05-15 10:43:59

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S-ADENOSYL-L-METHIONINE CHLORIDE SALT Properties

storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	H₂O: 100 mg/mL
form	Solid
color	Off-White to Dark Yellow
Stability	Hygroscopic
FDA UNII	B02SK72839

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes	Xn
Risk Statements	20/21/22-68/20/21/22
Safety Statements	36-45
WGK Germany	1
F	10-21

S-ADENOSYL-L-METHIONINE CHLORIDE SALT price More Price(8)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	AAA0004890	S-(5'-ADENOSYL)-L-METHIONINE CHLORIDE 95.00%	24346-00-7	5MG	$501.88	2021-12-16	Buy
Matrix Scientific	097918	5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-adenosine chloride 95+%	24346-00-7	250mg	$515	2021-12-16	Buy
AK Scientific	1800AB	5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-adenosinechloride	24346-00-7	250mg	$745	2021-12-16	Buy
American Custom Chemicals Corporation	AAA0004890	S-(5'-ADENOSYL)-L-METHIONINE CHLORIDE 95.00%	24346-00-7	250MG	$877.8	2021-12-16	Buy
Medical Isotopes, Inc.	19369	S-(5?-Adenosyl)-L-methionineChloride	24346-00-7	1g	$990	2021-12-16	Buy

Product number	Packaging	Price	Buy
AAA0004890	5MG	$501.88	Buy
097918	250mg	$515	Buy
1800AB	250mg	$745	Buy
AAA0004890	250MG	$877.8	Buy
19369	1g	$990	Buy

S-ADENOSYL-L-METHIONINE CHLORIDE SALT Chemical Properties,Uses,Production

Purification Methods

Purify it by ion exchange on Amberlite IRC-150 and eluting with 0.1-4M HCl. [Stolowitz & Minch J Am Chem Soc 103 6015 1981.] It has been isolated as the tri-reineckate salt by adding 2volumes of 1% solution of ammonium reineckate in 2% perchloric acid. The reineckate salt separates at once but is kept at 2o overnight. The salt is collected on a sintered glass funnel, washed with 0.5% of ammonium reineckate, dried (all operations at 2o) and stored at 2o. To obtain adenosylmethionine, the reineckate is dissolved in a small volume of methyl ethyl ketone (MEK) and centrifuged at room temperature to remove a small amount of solid. The clear dark red supernatant is extracted (in a separating funnel) with a slight excess of 0.1N H2SO4. The aqueous phase is re-extracted with fresh MEK until it is colourless. [Note that reineckates have UV absorption at 305nm ( 15,000), and the optical density at 305nm is used to detect and estimate reineckate ions.] MEK is removed from the aqueous layer containing adenosylmethionine sulfate; the pH is adjusted to 5.6-6.0 and extracted with two volumes of Et2O. The sulfate is obtained by evaporating the aqueous layer in vacuo. The hydrochloride can be obtained in the same way but using HCl instead of H2SO4. SAM-HCl has a solubility of 10% in H2O. The salts are stable in the cold at pH 4-6 but decompose in alkaline media. [Cantoni Biochemical Preparations 5 58 1957.] The purity of SAM can be determined by paper chromatography [Cantoni J Biol Chem 204 403 1953, Methods Enzymol 3 601 1957], electrophoretic methods or enzymic analysis [Cantoni & Vignos J Biol Chem 209 647 1954]. [Beilstein 26 III/IV 3676.]

S-ADENOSYL-L-METHIONINE CHLORIDE SALT Preparation Products And Raw materials

Raw materials

Preparation Products

S-ADENOSYL-L-METHIONINE CHLORIDE SALT Suppliers

Global( 58)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29271	58
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	sales@newcanbio.com	China	10027	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19915	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Young Lively PharminBlock Co.,Ltd	+undefined18600731423	jason_gao@yl-pharminblock.com	China	1944	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Hongene Biotech Corporation	021-64757213	info@hongene.com	China	672	61
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696;	info@hanhongsci.com	China	42982	64

Supplier	Advantage
career henan chemical co	58
Dideu Industries Group Limited	58
NewCan Biotech Limited	58
Nextpeptide Inc	58
TargetMol Chemicals Inc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Young Lively PharminBlock Co.,Ltd	58
J & K SCIENTIFIC LTD.	76
Hongene Biotech Corporation	61
Shanghai Hanhong Scientific Co.,Ltd.	64

View Lastest Price from S-ADENOSYL-L-METHIONINE CHLORIDE SALT manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-15	S-ADENOSYL-L-METHIONINE CHLORIDE SALT 24346-00-7	US $1.00 / g	100g	>98%	g/kg/Ton	Career Henan Chemical Co

S-ADENOSYL-L-METHIONINE CHLORIDE SALT
24346-00-7
US $1.00 / g
>98%
Career Henan Chemical Co

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SAM CHLORIDE ACTIVE METHIONINE ADENOSYL-L-METHIONINE, S-CHLORIDE SALT S-ADENOSYL-L-METHIONINE CHLORIDE S-ADENOSYL-L-METHIONINE CHLORIDE SALT S-ADENOSYL METHIONINE CHLORIDE SALT S-(5'-ADENOSYL)-L-METHIONINE CHLORIDE (3S)-5'-[(3-amino-3-carboxypropyl)methylsulphonio]-5'-deoxyadenosine chloride S-Adenosyl-5'-L-MethionineChlorideEx ADEMETHIONINECHLORIDE Active methionine, AdoMet, SAM chloride Active methionine chloride S-Adenosyl-5'-L-methionine chloride Einecs 246-184-8 ADENOSYL-L-METHIONINE CHLORIDE, S-(RG) S-(5′-Adenosyl)-L-methionine chloride,Active methionine, AdoMet, SAM chloride 5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-adenosine chloride SAM-E CHLORIDE SALT (2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(methyl)sulfaniumyl)butanoate hydrochloride SAM-Cl S-ADENOSYL-L-METHIONINE CHLORIDE SALT USP/EP/BP ((S)-3-Amino-3-carboxypropyl)(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonium chloride (2S)-2-amino-4-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonio)butanoate hydrochloride ADENOSYL-L-METHIONINE CHLORIDE, S- 24346-00-7 C15H23ClN6O5S C15H23N6O5SCl Enzyme Cofactor BioChemical Cancer Research Chemopreventive Agents Amino Acids & Derivatives Bases & Related Reagents Carbohydrates & Derivatives Nucleotides Sulfur & Selenium Compounds