3-(DIMETHYLAMINO)-1-(3-NITROPHENYL)-2-PROPEN-1-ONE
- CAS No.
- 115955-48-1
- Chemical Name:
- 3-(DIMETHYLAMINO)-1-(3-NITROPHENYL)-2-PROPEN-1-ONE
- Synonyms
- 3-(DIMETHYLAMINO)-1-(3-NITROPHENYL)-2-PROPEN-1-ONE;2-Propen-1-one, 3-(dimethylamino)-1-(3-nitrophenyl)-;(2E)-3-(Dimethylamino)-1-(3-nitrophenyl)prop-2-en-1-one
- CBNumber:
- CB4729934
- Molecular Formula:
- C11H12N2O3
- Molecular Weight:
- 220.22
- MDL Number:
- MFCD00024513
- MOL File:
- Mol file
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-(Dimethylamino)-1-(3-nitrophenyl)prop-2-en-1-one | D495110 | 100mg | $110 |
| 3-(Dimethylamino)-1-(3-nitrophenyl)prop-2-en-1-one | 130871 | 1g | $84 |
| (2E)-3-(Dimethylamino)-1-(3-nitrophenyl)prop-2-en-1-one | FD137190 | 250mg | $85 |
| 3-(Dimethylamino)-1-(3-nitrophenyl)prop-2-en-1-one | OR110306 | 1g | $108 |
| 3-(Dimethylamino)-1-(3-nitrophenyl)prop-2-en-1-one | 4956-1-25 | 1g | $128 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319 |
| Precautionary statements | P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312 |
| HazardClass | IRRITANT |
| HS Code | 2922390090 |
3-(DIMETHYLAMINO)-1-(3-NITROPHENYL)-2-PROPEN-1-ONE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | D495110 | 3-(Dimethylamino)-1-(3-nitrophenyl)prop-2-en-1-one | 115955-48-1 | 100mg | $110 | 2021-12-16 | Buy |
| Matrix Scientific | 130871 | 3-(Dimethylamino)-1-(3-nitrophenyl)prop-2-en-1-one | 115955-48-1 | 1g | $84 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD137190 | (2E)-3-(Dimethylamino)-1-(3-nitrophenyl)prop-2-en-1-one | 115955-48-1 | 250mg | $85 | 2021-12-16 | Buy |
| Apolloscientific | OR110306 | 3-(Dimethylamino)-1-(3-nitrophenyl)prop-2-en-1-one | 115955-48-1 | 1g | $108 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4956-1-25 | 3-(Dimethylamino)-1-(3-nitrophenyl)prop-2-en-1-one | 115955-48-1 | 1g | $128 | 2021-12-16 | Buy |
3-(DIMETHYLAMINO)-1-(3-NITROPHENYL)-2-PROPEN-1-ONE Chemical Properties,Uses,Production
Synthesis
4637-24-5
121-89-1
115955-48-1
To a 250 mL round bottom flask was added 16.5 g (100 mmol) of m-nitroacetophenone, 26.5 mL of N,N-dimethylformamide dimethyl acetal (200 mmol) and 100 mL of xylene. The reaction mixture was heated to 140 °C and kept for 12 hours. After completion of the reaction, the mixture was cooled to room temperature and the precipitate was collected by filtration. The precipitate was washed sequentially with petroleum ether and ethyl ether, and then purified by silica gel column chromatography (eluent: ethyl acetate/cyclohexane, 25/75, v/v) to afford 19.6 g of the yellow solid product, 3-(dimethylamino)-1-(3-nitrophenyl)prop-2-en-1-one, in 89% yield. The structure of the product was determined by 1H NMR (200 MHz, DMSO-d6) δ 8.59 (t, 1H), 8.42-8.23 (m, 1H), 7.81 (d, J = 12.1 Hz, 1H), 7.70 (t, J = 7.9 Hz, 1H), 5.89 (d, J = 12.1 Hz, 1H), 3.17 (s, 1H), 2.95 (s , 1H) and confirmed by 13C NMR (50 MHz, DMSO-d6) δ 182.8, 155.2, 147.9, 141.6, 133.4, 129.8, 125.1, 121.5, 90.3, 44.7, 37.3.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 8, p. 1780 - 1783
[2] Patent: US2007/219183, 2007, A1. Location in patent: Page/Page column 11
[3] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 10, p. 2735 - 2738
[4] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 24, p. 6890 - 6892
[5] Patent: US2006/63784, 2006, A1. Location in patent: Page/Page column 43
3-(DIMETHYLAMINO)-1-(3-NITROPHENYL)-2-PROPEN-1-ONE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Aromsyn Co., Ltd. | +86-0571-85585865 +8613336024896 | CB@aromsyn.com | China | 19183 | 58 |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8618662433356 | 3899766280@qq.com | China | 26362 | 58 |
| Aceschem Inc. | +1-817863-6948 +1-（817）863-6948 | sales@aceschem.com | United States | 19632 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Xinyanhe Pharmatech Co.,Ltd | 0519-85252752 15366845260 | taihuaren@vip.163.com | China | 1056 | 58 |
| Nanjing Chalf-Pharm Technology Co., Ltd. | 025-57018978 18251899859 | sales@chalf-pharm.com | China | 5881 | 50 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 89689 | 60 |
| Shanghai Chaolan Chemical Technology Center | 021-QQ：65489617 15618227136 | Sales@ATKchemical.com | China | 9550 | 58 |
