ChemicalBook >> CAS DataBase List >>Althiazide
Althiazide
- CAS No.
- 5588-16-9
- Chemical Name:
- Althiazide
- Synonyms
- P-1779;Altizid;CB 8093;CB-8093;Althizide;ALTHIAZIDE;Altizide CRS;Altizide (Y0000606);3-[(Allylthio)methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide;3-[(allylthio)methyl]-6-chloro-1,1-diketo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide
- CBNumber:
- CB4739720
- Molecular Formula:
- C11H14ClN3O4S3
- Molecular Weight:
- 383.89
- MDL Number:
- MFCD00063558
- MOL File:
- 5588-16-9.mol
Last updated:2023-08-23 10:21:02
| Melting point | 206-207° |
|---|---|
| Boiling point | 625.8±65.0 °C(Predicted) |
| Density | 1.502±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Practically insoluble in water, soluble in methanol, practically insoluble in dichloromethane. |
| pka | 8.33±0.40(Predicted) |
| color | White to Off-White |
| FDA UNII | GI8CB72B0D |
| EPA Substance Registry System | 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-[(2-propen-1-ylthio)methyl]-, 1,1-dioxide (5588-16-9) |
Althiazide price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0000606 | Altizide European Pharmacopoeia (EP) Reference Standard | 5588-16-9 | y0000606 | $220 | 2024-03-01 | Buy |
| Usbiological | 259084 | Althiazide | 5588-16-9 | 5mg | $446 | 2021-12-16 | Buy |
| TRC | A575775 | Althiazide | 5588-16-9 | 50mg | $790 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0007933 | ALTHIAZIDE 95.00% | 5588-16-9 | 100MG | $1871.1 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA17332 | Althiazide | 5588-16-9 | 25mg | $625 | 2021-12-16 | Buy |
Althiazide Chemical Properties,Uses,Production
Description
Althiazide, also known as altizide, is an agent belonging to the class of thiazide diuretics with antihypertensive activity. This aldosterone antagonist is often combined with spironolactone.
Chemical Properties
White Solid
Originator
Althiazide,Solchem
Uses
Diuretic and antihypertensive.
Definition
ChEBI: Althiazide is a benzothiadiazine. It is the thiazide and sulfonamide derivative.
Manufacturing Process
To 6.75 g (0.0225 mole) of 4-amino-2-chloro-5-(methylsulfamyl) benzenesulfonamide in 45 ml of dimethylformamide is added 4.86 g (0.03 mole) of dimethyl allylmercaptoacetal followed by 1.5 ml ethyl acetate saturated with hydrogen chloride gas. The solution is refluxed for 1.5 hours, cooled and added dropwise with stirring to ice/water. The resulting precipitate is filtered, dried and recrystallized from isopropanol. The recrystallization gave 4.0 g of 2-methyl-3-allylthiomethyl-6-chloro-7-sulfamyl-3,4-dihydro-1,2,4- benzothiadiazine-1,1-dioxide; M.P. 168.5-170°C.
Therapeutic Function
Diuretic, Antihypertensive
Althiazide Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 39)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9901 | 58 | |
| Cato Research Chemicals Inc. | 020-81960175 | min.he@cato-chem.com | China | 1958 | 55 |
| Cochemical Ltd. | 029-86115547 17791676824 | sales@cochemical.com | China | 3049 | 58 |
| ChemStrong Scientific Co.,Ltd | 0755-66853366 13670046396 | sales@chem-strong.com | China | 17982 | 56 |
| Chengdu Dianchun Technology Co., Ltd | 400-1166-196 18502815961 | cdhxsj@163.com | China | 14623 | 60 |
5588-16-9(Althiazide)Related Search:
ALTHIAZIDE
6-CHLORO-3,4-DIHYDRO-3-[(2-PROPENYLTHIO)METHYL]-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE
3-[(Allylthio)methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
P-1779
3-[(allylthio)methyl]-6-chloro-1,1-diketo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide
6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide
6-Chloro-3,4-dihydro-3-[(2-propen-1-ylthio)Methyl]-2H-1,2,4-benzothiadiazine-7-sulfonaMide 1,1-Dioxide
Althizide
Altizid
3-((allylthio)methyl)-6-chloro-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide
6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
Altizide CRS
(3RS)-6-Chloro-3-[(prop-2-enylsulfanyl)methyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-[(2-propen-1-ylthio)methyl]-, 1,1-dioxide
Altizide (Y0000606)
CB 8093
CB-8093
Althiazide
(3R)-3-[(Allylsulfanyl)methyl]-6-chloro-3,4-dihydro-2H-1,2,4-
benzothiadiazine-7-sulfonamide 1,1-dioxide
5588-16-9
C11H14ClN3O4S3
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