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S-1 METHANANDAMIDE

CAS No.
157182-50-8
Chemical Name:
S-1 METHANANDAMIDE
Synonyms
S-1 METHANANDAMIDE;S(-)-METHANANDAMIDE;S-1 Methanandamide Exclusive;S(-)-ARACHIDONYL-1'-HYDROXY-2'-PROPYLAMIDE;(S)-(-)-ARACHIDONOYL-1'-HYDROXY-2'-PROPYLAMIDE;N-(2-HYDROXY-1S-METHYLETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE;(5Z,8Z,11Z,14Z)-N-[(2S)-1-hydroxypropan-2-yl]icosa-5,8,11,14-tetraenamide;5,8,11,14-Eicosatetraenamide, N-[(1S)-2-hydroxy-1-methylethyl]-, (5Z,8Z,11Z,14Z)-
CBNumber:
CB4740139
Molecular Formula:
C23H39NO2
Molecular Weight:
361.56
MDL Number:
MFCD00674437
MOL File:
Mol file
Last updated:2023-06-08 09:03:09

S-1 METHANANDAMIDE Properties

Boiling point 529.0±50.0 °C(Predicted)
Density 0.935±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO;dimethyl formamide;acetonitril
form solution in ethanol.
pka 14.51±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

S-1 METHANANDAMIDE price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 90072 S-1 Methanandamide ≥98% 157182-50-8 5mg $53 2024-03-01 Buy
Cayman Chemical 90072 S-1 Methanandamide ≥98% 157182-50-8 10mg $96 2024-03-01 Buy
Cayman Chemical 90072 S-1 Methanandamide ≥98% 157182-50-8 25mg $214 2024-03-01 Buy
American Custom Chemicals Corporation CHM1015119 N-(2-HYDROXY-1S-METHYLETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE 95.00% 157182-50-8 5MG $501.92 2021-12-16 Buy
ApexBio Technology C5509 S-1Methanandamide 157182-50-8 10mg(solution) $108 2021-12-16 Buy
Product number Packaging Price Buy
90072 5mg $53 Buy
90072 10mg $96 Buy
90072 25mg $214 Buy
CHM1015119 5MG $501.92 Buy
C5509 10mg(solution) $108 Buy

S-1 METHANANDAMIDE Chemical Properties,Uses,Production

Definition

ChEBI: S-1 methanandamide is a carboximidic acid.

Biological Activity

s-1 methanandamide is a cb1 receptor ligand.the cannabinoid receptor type 1 (cb1), is a g protein-coupled cannabinoid receptor located mainly in the central and peripheral nervous system. cb1 is also expressed in several cells relating to metabolism, such as muscle cells, fat cells, liver cells, and the digestive tract. the cb1 receptor has been involved in the maintenance of homeostasis in health and disease, preventing the development of excessive neuronal activity, reducing pain and other inflammatory symptoms. enhanced receptor expression has been identified in human hepatocellular carcinoma tumor samples and human prostate cancer cells [2].s-1 methanandamide was a less potent than the c-1 (r) methyl isomer when binding with cb1 receptor. s-1 methanandamide inhibited electrically evoked contractions in isolated mouse vasa deferentia with an ic50 value of 230 nm. the binding affinity of s-1 methanandamide for cb1 receptors was less than that of aea, with a ki of 175 nm for the displacement of radiolabeled cp 55,940 [1].

References

[1] abadji v, lin s, taha g, et al. (r)-methanandamide: a chiral novel anandamide possessing higher potency and metabolic stability[j]. journal of medicinal chemistry, 1994, 37(12): 1889-1893.
[2] howlett a c. cannabinoid receptor signaling[m]//cannabinoids. springer berlin heidelberg, 2005: 53-79.

S-1 METHANANDAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

S-1 METHANANDAMIDE Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
ApexBio Technology -- sales@apexbt.com United States 6254 58
Supplier Advantage
TargetMol Chemicals Inc. 58
ApexBio Technology 58

157182-50-8(S-1 METHANANDAMIDE)Related Search:

N-(2-HYDROXY-1S-METHYLETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE S-1 METHANANDAMIDE S(-)-METHANANDAMIDE (S)-(-)-ARACHIDONOYL-1'-HYDROXY-2'-PROPYLAMIDE S(-)-ARACHIDONYL-1'-HYDROXY-2'-PROPYLAMIDE S-1 Methanandamide Exclusive 5,8,11,14-Eicosatetraenamide, N-[(1S)-2-hydroxy-1-methylethyl]-, (5Z,8Z,11Z,14Z)- (5Z,8Z,11Z,14Z)-N-[(2S)-1-hydroxypropan-2-yl]icosa-5,8,11,14-tetraenamide 157182-50-8