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Aluminium phosphate

CAS No.
7784-30-7
Chemical Name:
Aluminium phosphate
Synonyms
ALUMINUM PHOSPHATE;Alminum phosphate;Aluminium Phosphite;ALUMINUM ORTHOPHOSPHATE;ffb32;aluphos;phosphalugel;ALUMPHOSPHATE;ALUMINOPHOSPHATE;uminum phosphate
CBNumber:
CB4741378
Molecular Formula:
AlO4P
Molecular Weight:
121.95
MDL Number:
MFCD00003430
MOL File:
7784-30-7.mol
MSDS File:
SDS
Last updated:2023-12-27 16:49:21

Aluminium phosphate Properties

Melting point 1500 °C
Density 2.56 g/mL at 25 °C (lit.)
storage temp. Inert atmosphere,Room Temperature
solubility Very slightly soluble in water, practically insoluble in alcohol. It dissolves in dilute solutions of mineral acids and alkali hydroxides.
form Powder
Specific Gravity 2.566
color White
Water Solubility Insoluble
Merck 14,358
Solubility Product Constant (Ksp) pKsp: 20.01
Dielectric constant 6.0(Ambient)
Exposure limits ACGIH: TWA 1 mg/m3
InChI InChI=1S/Al.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3
InChIKey ILRRQNADMUWWFW-UHFFFAOYSA-K
SMILES [Al+3].P([O-])([O-])([O-])=O
CAS DataBase Reference 7784-30-7(CAS DataBase Reference)
FDA UNII F92V3S521O
ATC code A02AB03
EPA Substance Registry System Monoaluminum phosphate (7784-30-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H318-H314
Precautionary statements  P280-P305+P351+P338-P310-P260h-P301+P330+P331-P303+P361+P353-P405-P501a
Hazard Codes  C
Risk Statements  34
Safety Statements  26-36/37/39-45
RIDADR  UN 3260 8/PG 2
WGK Germany  1
RTECS  TB6450000
TSCA  Yes
HazardClass  8
HS Code  28352990
Toxicity LD50 oral in mouse: > 5gm/kg
NFPA 704
1
2 0

Aluminium phosphate price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 341452 Aluminum phosphate reagent grade 7784-30-7 100g $37.2 2024-03-01 Buy
Sigma-Aldrich 255963 Aluminum phosphate 99.99% trace metals basis 7784-30-7 10g $230 2024-03-01 Buy
Alfa Aesar 010628 Aluminum phosphate, Puratronic?, 99.99% (metals basis) 7784-30-7 5g $80.65 2024-03-01 Buy
Alfa Aesar 010628 Aluminum phosphate, Puratronic?, 99.99% (metals basis) 7784-30-7 25g $346 2023-06-20 Buy
Sigma-Aldrich 341452 Aluminum phosphate reagent grade 7784-30-7 500g $133 2024-03-01 Buy
Product number Packaging Price Buy
341452 100g $37.2 Buy
255963 10g $230 Buy
010628 5g $80.65 Buy
010628 25g $346 Buy
341452 500g $133 Buy

Aluminium phosphate Chemical Properties,Uses,Production

Description

Aluminium phosphate occurs in nature as the mineral, berlinite. Also, it occurs in nature in minerals, amblygonite, [NaAl(PO4)(OH)]; augelite, [Al2(PO4)(OH)3]; lazulite, [(Mg,Fe)Al2(PO4)2(OH)2]; variscite [(Al,Fe3+)(PO4)•2H2O]; and wavellite, [Al3(OH)3•(PO4)2•5H2O]. It is used as flux for ceramics; as cement in combination with calcium sulfate and sodium silicate; and in the manufacture of special glasses. It is also used in dried gel and therapeutically as an antacid.

Chemical Properties

Aluminum phosphate adjuvant is a white hydrogel that sediments slowly and forms a clear supernatant.

Chemical Properties

Aluminum orthophosphate is a white crystalline solid which is often used in liquid or gel form

Physical properties

White powdery solid (rhombic plate); the mineral berlinite (AlPO4) has hexagonal quartz-like structure; refractive index 1.546; mp > 1,500°C; density 2.566 g/cu3; insoluble in water and alcohol; Ksp 9.83x10-10 very slightly soluble in HCl or HNO3.

Occurrence

The compound occurs in nature as the mineral, berlinite. Also, it occurs in nature in minerals, amblygonite, [NaAl(PO4)(OH)]; augelite, [Al2(PO4)(OH)3]; lazulite, [(Mg,Fe)Al2(PO4)2(OH)2]; variscite [(Al,Fe3+)(PO4)?2H2O]; and wavellite, [Al3(OH)3?(PO4)2?5H2O]. It is used as flux for ceramics; as cement in combination with calcium sulfate and sodium silicate; and in the manufacture of special glasses. It is also used in dried gel and therapeutically as an antacid.

Uses

As a flux for ceramics, preparation of dental cement, cement with calcium sulfate and sodium silicate, special glasses, as gel in pharmacy.Aluminum phosphate is used as catalysts, molecular sieves, flux for ceramics and as a gel in pharmacy. It is employed in the preparation of dental cement, emollients and fire-resistant coating. It plays an important role as an anti-fouling agent in textile industry.

Uses

Antacid; vaccine adjuvant

Production Methods

Aluminum phosphate adjuvant is formed by the reaction of a solution of aluminum chloride and phosphoric acid with alkali hydroxide.

Preparation

It is prepared by treating sodium aluminate with phosphoric acid.

brand name

Phosphaljel (Wyeth-Ayerst).

General Description

A colorless liquid. Insoluble in water. Corrosive to metals and tissue.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

An acid. The resulting aqueous solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.

Hazard

Solutions are corrosive to tissue.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.

Flammability and Explosibility

Non flammable

Pharmaceutical Applications

Aluminum phosphate adjuvant is used in parenteral human and veterinary vaccines.It activates Th2 immune responses, including IgG and IgE antibody responses.

Clinical Use

Phalu Gel's main active ingredient is aluminum Phosphorus. Aluminum Phosphate works to reduce excess stomach acid. This gel suspension, when taken to the stomach, will form a protective layer on the surface of the gastrointestinal mucosa, similar to the effect of mucus or mucosal protective factors to help cover the stomach from the impact of fluids. The aluminum phosphate layer in the stomach has a smooth dispersion effect, going to the ulcers in the stomach and making them heal faster, making the patient feel more comfortable and less painful. Aluminum Phosphorus, when used, does not affect the intestinal absorption of Phosphorus. Phalu-Gel will quickly reduce the pain of stomach ulcers and the discomfort of excess acid, help heal the ulcers quickly, and make the patient feel comfortable right away.Aluminum hydroxide, aluminum phosphate, and potassium aluminum sulfate (alum) are used as adjuvants in vaccines designed to stimulate systemic immunity. Aluminum salts are used in DPT, pneumocccal conjugate, hepatitis A, papilloma, anthrax, and rabies vaccines. Like other systemic adjuvants, they form an insoluble depot and slowly release the antigen, which stimulates an antibody response.

Safety Profile

Corrosive to the eyes, skin, and mucous membranes. When heated to decomposition it emits toxic fumes of POx. Used as an antacid and as a cement component, flux for ceramics, dental cement, glass, and gels. See also ALUMINUM COMPOUNDS and PHOSPHATES

Safety

Aluminum phosphate adjuvant is intended for use in parenteral vaccines and is generally regarded as safe. It may cause mild irritation, dryness, and dermatitis on skin contact. It may also cause redness, conjunctivitis, and short-term mild irritation on eye contact. Ingestion of large amounts of aluminum phosphate adjuvant may cause respiratory irritation with nausea, vomiting, and constipation. Inhalation is unlikely, although the dried product may cause respiratory irritation and cough. Type I hypersensitivity reactions following parenteral administration have also been reported.

Potential Exposure

Used as a flux in ceramics; in dental cements; in the manufacture of special glasses, paints and varnishes, cosmetics; making pulp and paper; as an antacid.

storage

Aluminum phosphate adjuvant is stable for at least 2 years when stored at 4–308℃ in well-sealed inert containers. It must not be allowed to freeze as the hydrated colloid structure will be irreversibly damaged.

Shipping

UN1760 Corrosive liquids, n.o.s., Hazard class: 8; Labels: 8-Corrosive material, Technical Name Required. UN3260 Corrosive solid, acidic, inorganic, n.o.s., Hazard class: 8; Labels: 8-Corrosive material, Technical Name Required.

Incompatibilities

A strong oxidizer; keep away from combustible materials. Violent reaction with reducing agents; strong bases. Material is an inorganic acid and will react, possibly violently, with bases; corrosive to metals, some plastics and body tissues

Incompatibilities

The point of zero charge is related directly to the Al : P atomic ratio. Therefore, the substitution of additional phosphate groups for hydroxyl groups will lower the point of zero charge. Substitution of carbonate, sulfate, or borate ions for hydroxyl groups will also lower the point of zero charge.

Regulatory Status

GRAS listed. Accepted for use in human and veterinary vaccines in Europe and the USA. The limits for use in human vaccines are 0.85 mg aluminum/dose (FDA) and 1.25 mg aluminum/dose (WHO). There are no established limits for use in veterinary vaccines. Reported in the EPA TSCA Inventory.

Aluminium phosphate Preparation Products And Raw materials

Global( 235)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5988 58
Hebei Jingbo New Material Technology Co., Ltd
+8619931165850 hbjbtech@163.com China 1000 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21700 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5909 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569265 +86-18612256290 1056@dideu.com China 3959 58
Antai Fine Chemical Technology Co.,Limited
18503026267 info@antaichem.com CHINA 9641 58

View Lastest Price from Aluminium phosphate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Aluminium phosphate pictures 2023-12-27 Aluminium phosphate
7784-30-7
US $8.00 / kg 1kg 99% 2000000 Hebei Jingbo New Material Technology Co., Ltd
Aluminium phosphate pictures 2023-09-12 Aluminium phosphate
7784-30-7
US $0.00-0.00 / kg 1kg P2O5 %:60%-70%;Al2O3 :30%-40% 100tons Hebei Yanxi Chemical Co., Ltd.
[Phosphato(3-)-κ3O,O',O'']aluminium pictures 2023-02-13 [Phosphato(3-)-κ3O,O',O'']aluminium
7784-30-7
US $90.00 / kg 1kg 99% 100MT Hebei baicao biology science and technology co., ltd
  • Aluminium phosphate pictures
  • Aluminium phosphate
    7784-30-7
  • US $0.00-0.00 / kg
  • P2O5 %:60%-70%;Al2O3 :30%-40%
  • Hebei Yanxi Chemical Co., Ltd.

Aluminium phosphate Spectrum

Aluminum monohydrogen phosphate Dialuminum phosphate Primary alminum phosphate Aluminum phosphate, Puratronic (metals basis) "Aluminium phosphate, tech." AluMiniuM phosphate Powder ALUMINIUM PHOSPHATE BASIC ALUMINIUM PHOSPHATE ALUMINUM PHOSPHATE TRIBASIC ALUMINUM O-PHOSPHATE Aluminum phosphate 99.99% trace metals basis Aluminum phosphate reagent grade aluminiumphosphat aluminiumphosphate,tribasic aluminophosphoricacid aluminumacidphosphate aluminummonophosphate aluminumphosphate(1:1) aluminumphosphate(non-specificname) aluminumphosphate,solution aluphos ffb32 monoaluminumphosphate phosphalugel Phosphoricacid,aluminumsalt(1:1) ALUMINUM PHOSPHATE, 99.99% ALUMINUM PHOSPHATE ANHYDROUS HEAVY ALUMINIUM PHOSPHATE ANHYDROUS, TECHNICAL AluminiumOrthophoshateTribasic,Gpr Aluminumphosphate,Puratronic,99.99%(metalsbasis) aluminium orthophosphate Aluminium phosphate, pure aluminum phosphate, puratronic ALUMPHOSPHATE ALUMINOPHOSPHATE Aluminiumorthophosphat ALUMINUM PHOSPHATE: TECH. Aluminum phosphate, Puratronic(R), 99.99% (metals basis) Aluminum phosphate: (Phosphoric acid, aluminum salt (1:1), solution) [Phosphato(3-)-κ3O,O',O'']aluminium uminum phosphate aluminium trippolyhosphate Aluminium phosphate USP/EP/BP Aluminium phosphate ISO 9001:2015 REACH Aluminum phosphate (AlPO4) Alminum phosphate ALUMINUM PHOSPHATE ALUMINUM ORTHOPHOSPHATE Aluminium Phosphite 7784-30-7 AlPO4 Aluminum Salts Metal and Ceramic Science Salts Inorganics Industrial/Fine Chemicals