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Aluminium phosphate

Aluminium phosphate
Aluminium phosphate structure
CAS No.
7784-30-7
Chemical Name:
Aluminium phosphate
Synonyms
ffb32;aluphos;phosphalugel;ALUMPHOSPHATE;ALUMINOPHOSPHATE;uminum phosphate;Alminum phosphate;aluminiumphosphat;ALUMINUM PHOSPHATE;ALUMINIUM PHOSPHATE
CBNumber:
CB4741378
Molecular Formula:
AlO4P
Formula Weight:
121.95
MOL File:
7784-30-7.mol

Aluminium phosphate Properties

Melting point:
1500 °C
Density 
2.56 g/mL at 25 °C (lit.)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Very slightly soluble in water, practically insoluble in alcohol. It dissolves in dilute solutions of mineral acids and alkali hydroxides.
form 
Powder
color 
White
Specific Gravity
2.566
Water Solubility 
Insoluble
Merck 
14,358
Solubility Product Constant (Ksp)
pKsp: 20.01
CAS DataBase Reference
7784-30-7(CAS DataBase Reference)
FDA UNII
F92V3S521O
ATC code
A02AB03
EPA Substance Registry System
Monoaluminum phosphate (7784-30-7)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H318-H314
Precautionary statements  P280-P305+P351+P338-P310-P260h-P301+P330+P331-P303+P361+P353-P405-P501a
Hazard Codes  C
Risk Statements  34
Safety Statements  26-36/37/39-45
RIDADR  UN 3260 8/PG 2
WGK Germany  1
RTECS  TB6450000
TSCA  Yes
HazardClass  8
HS Code  28352990
Toxicity LD50 oral in mouse: > 5gm/kg

Aluminium phosphate price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 341452 Aluminum phosphate reagent grade 7784-30-7 100g $31.5 2021-03-22 Buy
Sigma-Aldrich 255963 Aluminum phosphate 99.99% trace metals basis 7784-30-7 10g $194 2021-03-22 Buy
Alfa Aesar 010628 Aluminum phosphate, Puratronic?, 99.99% (metals basis) 7784-30-7 25g $306 2021-03-22 Buy
Alfa Aesar 010628 Aluminum phosphate, Puratronic?, 99.99% (metals basis) 7784-30-7 5g $78.5 2021-03-22 Buy
Sigma-Aldrich 341452 Aluminum phosphate reagent grade 7784-30-7 500g $113 2021-03-22 Buy

Aluminium phosphate Chemical Properties,Uses,Production

Description

Aluminium phosphate occurs in nature as the mineral, berlinite. Also, it occurs in nature in minerals, amblygonite, [NaAl(PO4)(OH)]; augelite, [Al2(PO4)(OH)3]; lazulite, [(Mg,Fe)Al2(PO4)2(OH)2]; variscite [(Al,Fe3+)(PO4)•2H2O]; and wavellite, [Al3(OH)3•(PO4)2•5H2O]. It is used as flux for ceramics; as cement in combination with calcium sulfate and sodium silicate; and in the manufacture of special glasses. It is also used in dried gel and therapeutically as an antacid.

Chemical Properties

White or almost white powder.

Chemical Properties

Aluminum orthophosphate is a white crystalline solid which is often used in liquid or gel form

Chemical Properties

Aluminum phosphate adjuvant is a white hydrogel that sediments slowly and forms a clear supernatant.

Physical properties

White powdery solid (rhombic plate); the mineral berlinite (AlPO4) has hexagonal quartz-like structure; refractive index 1.546; mp > 1,500°C; density 2.566 g/cu3; insoluble in water and alcohol; Ksp 9.83x10-10 very slightly soluble in HCl or HNO3.

Occurrence

The compound occurs in nature as the mineral, berlinite. Also, it occurs in nature in minerals, amblygonite, [NaAl(PO4)(OH)]; augelite, [Al2(PO4)(OH)3]; lazulite, [(Mg,Fe)Al2(PO4)2(OH)2]; variscite [(Al,Fe3+)(PO4)?2H2O]; and wavellite, [Al3(OH)3?(PO4)2?5H2O]. It is used as flux for ceramics; as cement in combination with calcium sulfate and sodium silicate; and in the manufacture of special glasses. It is also used in dried gel and therapeutically as an antacid.

Uses

Antacid; vaccine adjuvant

Production Methods

Aluminum phosphate adjuvant is formed by the reaction of a solution of aluminum chloride and phosphoric acid with alkali hydroxide.

Preparation

It is prepared by treating sodium aluminate with phosphoric acid.

brand name

Phosphaljel (Wyeth-Ayerst).

General Description

A colorless liquid. Insoluble in water. Corrosive to metals and tissue.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

An acid. The resulting aqueous solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.

Hazard

Solutions are corrosive to tissue.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.

Pharmaceutical Applications

Aluminum phosphate adjuvant is used in parenteral human and veterinary vaccines.It activates Th2 immune responses, including IgG and IgE antibody responses.

Safety Profile

Corrosive to the eyes, skin, and mucous membranes. When heated to decomposition it emits toxic fumes of POx. Used as an antacid and as a cement component, flux for ceramics, dental cement, glass, and gels. See also ALUMINUM COMPOUNDS and PHOSPHATES

Safety

Aluminum phosphate adjuvant is intended for use in parenteral vaccines and is generally regarded as safe. It may cause mild irritation, dryness, and dermatitis on skin contact. It may also cause redness, conjunctivitis, and short-term mild irritation on eye contact. Ingestion of large amounts of aluminum phosphate adjuvant may cause respiratory irritation with nausea, vomiting, and constipation. Inhalation is unlikely, although the dried product may cause respiratory irritation and cough. Type I hypersensitivity reactions following parenteral administration have also been reported.

Potential Exposure

Used as a flux in ceramics; in dental cements; in the manufacture of special glasses, paints and varnishes, cosmetics; making pulp and paper; as an antacid.

storage

Aluminum phosphate adjuvant is stable for at least 2 years when stored at 4–308℃ in well-sealed inert containers. It must not be allowed to freeze as the hydrated colloid structure will be irreversibly damaged.

Shipping

UN1760 Corrosive liquids, n.o.s., Hazard class: 8; Labels: 8-Corrosive material, Technical Name Required. UN3260 Corrosive solid, acidic, inorganic, n.o.s., Hazard class: 8; Labels: 8-Corrosive material, Technical Name Required.

Incompatibilities

The point of zero charge is related directly to the Al : P atomic ratio. Therefore, the substitution of additional phosphate groups for hydroxyl groups will lower the point of zero charge. Substitution of carbonate, sulfate, or borate ions for hydroxyl groups will also lower the point of zero charge.

Incompatibilities

A strong oxidizer; keep away from combustible materials. Violent reaction with reducing agents; strong bases. Material is an inorganic acid and will react, possibly violently, with bases; corrosive to metals, some plastics and body tissues

Regulatory Status

GRAS listed. Accepted for use in human and veterinary vaccines in Europe and the USA. The limits for use in human vaccines are 0.85 mg aluminum/dose (FDA) and 1.25 mg aluminum/dose (WHO). There are no established limits for use in veterinary vaccines. Reported in the EPA TSCA Inventory.

Aluminium phosphate Preparation Products And Raw materials

Raw materials

Preparation Products


Aluminium phosphate Suppliers

Global( 161)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 26762 60
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6369 58
Shandong chuangyingchemical Co., Ltd.
18853181302
sale@chuangyingchem.com CHINA 5917 58
Shaanxi Dideu Medichem Co. Ltd
13772537765
029-88380327 1010@dideu.com CHINA 3993 58
Zhuozhou Wenxi import and Export Co., Ltd
+8613111626072 (WhatsApp)
Wechat: +8613111626072 Wickr me: waynehu zzwenxi@126.com CHINA 13187 58
Antai Fine Chemical Technology Co.,Limited
18503026267
info@antaichem.com CHINA 9664 58
SIMAGCHEM CORP
13806087780 +86 13806087780
shaobowang@simagchem.com CHINA 17505 58

View Lastest Price from Aluminium phosphate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-08-03 Aluminium phosphate USP/EP/BP
7784-30-7
US $1.10 / g 1g 0.999 100 Tons min Dideu Industries Group Limited
2021-07-20 Aluminium phosphate
7784-30-7
US $1.00-1.00 / Kg/Bag 1g 99% 50tons Shaanxi Dideu Medichem Co. Ltd
2021-07-13 Aluminium phosphate
7784-30-7
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

Aluminium phosphate Spectrum


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