2-Benzoylbenzoic acid
- CAS No.
- 85-52-9
- Chemical Name:
- 2-Benzoylbenzoic acid
- Synonyms
- OBBA;skp10a;AKOS BBS-00000803;RARECHEM AL BO 1426;o-benzoyl-benzoicaci;2-benzoyl-benzoicaci;o-Carboxybenzophenone;2-BENZOYLBENZOIC ACID;2-CARBOXYBENZOPHENONE;OTAVA-BB BB7020401721
- CBNumber:
- CB4741530
- Molecular Formula:
- C14H10O3
- Molecular Weight:
- 226.23
- MDL Number:
- MFCD00002472
- MOL File:
- 85-52-9.mol
- MSDS File:
- SDS
| Melting point | 126-129 °C (lit.) |
|---|---|
| Boiling point | 257-265 °C (lit.) |
| Density | 1.2022 (rough estimate) |
| refractive index | 1.5767 (estimate) |
| Flash point | 257°C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Crystalline Powder |
| pka | pK1: 3.54 (25°C) |
| color | Almost white to slightly beige |
| Water Solubility | 284mg/L at 20℃ |
| BRN | 1107841 |
| InChIKey | FGTYTUFKXYPTML-UHFFFAOYSA-N |
| LogP | 1.4 at 35℃ |
| CAS DataBase Reference | 85-52-9(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 1N20Y812XW |
| NIST Chemistry Reference | Benzoic acid, 2-benzoyl-(85-52-9) |
| EPA Substance Registry System | Benzoic acid, 2-benzoyl- (85-52-9) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P280g-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | DG3600000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29183000 | |||||||||
| Hazardous Substances Data | 85-52-9(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 orl-rat: 4600 mg/kg GTPZAB 15(11),52,71 | |||||||||
| NFPA 704 |
|
2-Benzoylbenzoic acid price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | B12385 | 2-Benzoylbenzoic acid 98% | 85-52-9 | 25g | $24.36 | 2024-03-01 | Buy |
| Sigma-Aldrich | B12385 | 2-Benzoylbenzoic acid 98% | 85-52-9 | 500g | $161 | 2024-03-01 | Buy |
| TCI Chemical | B0103 | 2-Benzoylbenzoic Acid >99.0%(T) | 85-52-9 | 25g | $21 | 2024-03-01 | Buy |
| Alfa Aesar | A13281 | 2-Benzoylbenzoic acid 98+% | 85-52-9 | 50g | $33.65 | 2024-03-01 | Buy |
| Alfa Aesar | A13281 | 2-Benzoylbenzoic acid, 98+% | 85-52-9 | 250g | $91.65 | 2024-03-01 | Buy |
2-Benzoylbenzoic acid Chemical Properties,Uses,Production
Synthesis
In the presence of aluminum trichloride, phthalic anhydride and benzene are condensed and obtained by hydrolysis. The hydrochloric acid gas by-product in the reaction should preferably be absorbed into dilute hydrochloric acid for subsequent use. The industrial benzoylbenzoic acid is white to beige powder, the purity is above 97%, and the initial melting point of the dry product is ≥126.0%.
Chemical Properties
ALMOST WHITE TO SLIGHTLY BEIGE CRYSTALLINE POWDER
Uses
2-Benzoylbenzoic Acid is a reagent that is used in the synthesis of BzATP Triethylammonium Salt, which is a selective P2X purinergic agonist. It is more potent than ATP at homodimeric P2X7 receptors.
Synthesis Reference(s)
Journal of the American Chemical Society, 70, p. 2758, 1948 DOI: 10.1021/ja01188a035
The Journal of Organic Chemistry, 39, p. 2051, 1974 DOI: 10.1021/jo00928a016
Flammability and Explosibility
Not classified
Safety Profile
Moderately toxic by ingestion.When heated to decomposition it emits acrid smoke andirritating vapors.
Purification Methods
Recrystallise the acid from *C6H6 or cyclohexane, but it is best recrystallised by dissolving in a small volume of hot toluene and then adding just enough pet ether to cause turbidity, and cool. Dry it in a low vacuum at 80o. It can be sublimed at 230-240o/0.3mm [Bray et al. J Chem Soc 265 1957]. The S-benzylisothiuronium salt has m 177-178o (from EtOH). [Lewenz & Serijan J Am Chem Soc 75 4087 1953, Beilstein 10 H 747, 10 IV 2977.]
2-Benzoylbenzoic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Domen International Co., Ltd | +8613636585389 | martin@domen.com.cn | China | 209 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12822 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5878 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18140 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20254 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +852-6619 3215 +86-17731935328 | sales03@chemcn.cn | China | 970 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21631 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
View Lastest Price from 2-Benzoylbenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-03-19 | 2-Benzoylbenzoic acid
85-52-9
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd | |
 |
2025-03-19 | 2-Benzoylbenzoic acid
85-52-9
|
US $180.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2025-03-04 | 2-Benzoylbenzoic acid
85-52-9
|
US $60.00 / kg | 1kg | 99% | 1000 | hebei hongtan Biotechnology Co., Ltd |
-
- 2-Benzoylbenzoic acid
85-52-9
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- 2-Benzoylbenzoic acid
85-52-9
- US $180.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- 2-Benzoylbenzoic acid
85-52-9
- US $60.00 / kg
- 99%
- hebei hongtan Biotechnology Co., Ltd