ChemicalBook
Chinese Japanese Germany Korea

Silver sulfadiazine

Silver sulfadiazine
Silver sulfadiazine structure
CAS No.
22199-08-2
Chemical Name:
Silver sulfadiazine
Synonyms
SD-Ag;geben;Dermazin;Nsc625324;dermazine;flamazine;silvadene;Flammazine;SULPHADIAZINE-AG;Silver Sulfdiazine
CBNumber:
CB4744940
Molecular Formula:
C10H9AgN4O2S
Formula Weight:
357.14
MOL File:
22199-08-2.mol

Silver sulfadiazine Properties

Melting point:
285 °C (dec.)(lit.)
storage temp. 
Hygroscopic, Refrigerator, Under Inert Atmosphere
form 
powder
Merck 
14,8903
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
UEJSSZHHYBHCEL-UHFFFAOYSA-N
CAS DataBase Reference
22199-08-2(CAS DataBase Reference)

SAFETY

Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  2
RTECS  WP1950000
HazardClass  IRRITANT

Silver sulfadiazine price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 481181 Silver(I) sulfadiazine 98% 22199-08-2 5g $50.2 2018-11-13 Buy
Sigma-Aldrich 1612608 Silver sulfadiazine United States Pharmacopeia (USP) Reference Standard 22199-08-2 200mg $348 2018-11-13 Buy
TCI Chemical S0595 Silver Sulfadiazine >98.0%(HPLC)(T) 22199-08-2 5g $56 2018-11-22 Buy
TCI Chemical S0595 Silver Sulfadiazine >98.0%(HPLC)(T) 22199-08-2 25g $167 2018-11-22 Buy
Sigma-Aldrich 481181 Silver(I) sulfadiazine 98% 22199-08-2 25g $177 2018-11-13 Buy

Silver sulfadiazine Chemical Properties,Uses,Production

Chemical Properties

solid

Uses

Indicated as an adjunct for the prevention and treatment of wound sepsis in patients with second- and third-degree burns.

Uses

Coordination compound. Antibacterial

Pharmaceutical Applications

Silver sulfadiazine is indicated for the prophylaxis and treatment of infections in burn wounds. Silver sulfadiazine is highly insoluble in water, and as a result, it does not cause hypochloraemia in burns in contrast to silver nitrate.
The active ingredient silver sulfadiazine is a sulfur-derived topical antibacterial used primarily on secondand third-degree burns. It is known to be active against many Gram-negative and Gram-positive bacteria as well as against yeast. The cream is kept applied to the burned skin at all times for the duration of the healing period or until a graft is applied. It prevents the growth of a wide array of bacteria, as well as yeast, on the damaged skin. Caution has to be given to large-area application as sulfadiazine levels in the plasma may well reach therapeutic levels that can cause side effects.

Pharmaceutical Applications

Silver sulfadiazine is extremely insoluble. In addition to the usual activity of sulfonamides it exhibits activity – almost certainly attributable to the silver component – against Ps. aeruginosa and some fungi.
It is variably absorbed after topical application depending on the integrity of the skin. Toxic concentrations may be achieved in patients with extensive burns. It is used topically, mainly for burns, pressure sores and leg ulcers. Central venous catheters impregnated with chlorhexidine and silver sulfadiazine have been developed to reduce bacterial colonization. Other suggested uses include the prevention of infection in skin graft donor sites and cord care in newborn infants.

Clinical Use

The silver salt of sulfadiazine applied in a water-misciblecream base has proved to be an effective topical antimicrobialagent, especially against Pseudomonas spp. This is particularlysignificant in burn therapy because pseudomonadsare often responsible for failures in therapy. The salt is onlyslightly soluble and does not penetrate the cell wall butacts on the external cell structure. Studies using radioactivesilver have shown essentially no absorption into body fluids.Sulfadiazine levels in the serum were about 0.5 to2 mg/100 mL.
This preparation is reported to be easier to use thanother standard burn treatments, such as application offreshly prepared dilute silver nitrate solutions or mafenideointment.

Silver sulfadiazine Preparation Products And Raw materials

Raw materials

Preparation Products


Silver sulfadiazine Suppliers

Global( 228)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21990 58
Shanghai Bojing Chemical Co.,Ltd.
+86-21-37122233
+86-21-37127788 Candy@bj-chem.com CHINA 495 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32457 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 bruce@xrdchem.cn CHINA 541 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 24196 60
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24001 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20095 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 4669 58

View Lastest Price from Silver sulfadiazine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-20 Silver sulfadiazine
22199-08-2
US $1.00 / KG 1G 98% 100KG career henan chemical co
2018-08-08 Silver sulfadiazine
22199-08-2
US $1.00 / KG 1KG 98% 1tons career henan chemical co

22199-08-2(Silver sulfadiazine)Related Search:


  • SILVER(I) SULFADIAZINE
  • silver (4-aminophenyl)sulfonyl-pyrimidin-2-yl-azanide
  • SILVER SULPHADIAZINE
  • SILVER SULFADIAZINE
  • SULPHADIAZINE-AG
  • SULFADIAZINE SILVER
  • 4-amino-n-(2-pyrimidinyl)benzenesulfonamidesilversalt
  • 4-amino-n-2-pyrimidinylbenzenesulfonamide monosilver salt
  • (4-amino-N-pyrimidin-2-ylbenzenesulphonamidato-NN,O1)silver
  • SILVER(I) SULFADIAZINE 98%
  • Silver, 4-amino-N-(2-pyrimidinyl-.kappa.N1)benzenesulfonamidato-.kappa.O-
  • SILVERSULFADIAZINE,MICRONIZED
  • SILVERSULFADIAZINE,MICRONIZED,USP
  • sulfadiazine silver,SD-Ag
  • Sulfadiazine,Siliver salt
  • [4-Amino-N-(2-pyrimidinyl-kN1)benzenesulfonamidato-kO]silver
  • 4-Amino-N-2-pyrimidinylbenzenesulfonamide Silver Complex
  • Dermazin
  • Flammazine
  • 4-Amino-N-2-pyrimidinylbenzenesulfonamide monosilver(1+) salt
  • Sulfadiazine sailver salt
  • Benzenesulfonamide,4-amino-N-2-pyrimidinyl-, silver complex
  • Nsc625324
  • Silver,(4-amino-N-2-pyrimidinylbenzenesulfonamidato-nn,o1)-
  • Sulfadiazine silversilvadene
  • Silver Sulfdiazine
  • SD-Ag
  • Silver Sulfadiazine (200 mg)
  • -
  • 4-amino-n-2-pyrimidinyl-benzenesulfonamidmonosilver(1+)salt
  • dermazine
  • flamazine
  • geben
  • n(sup1)-2-pyrimidinyl-sulfanilamidmonosilver(1+)salt
  • silvadene
  • sulfadiazinesilversalt
  • Silver,[4-aMino-N-(2-pyriMidinyl-kN1)benzenesulfonaMidato-kO]-
  • Silver suifadiazine
  • (4-aminophenyl)sulfonyl-pyrimidin-2-ylazanide
  • Sulfadiazine silver Sulfadiazine Silver Salt SD-Ag
  • silver(1+) sulfadiazinate
  • 722199-08-2
  • C10H9AgN4O2S
  • Ag (Silver) Compounds
  • Antibiotics for Research and Experimental Use
  • Biochemistry
  • Classes of Metal Compounds
  • Sulfonamides (Antibiotics for Research and Experimental Use)
  • Transition Metal Compounds
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
  • API
  • 22199-08-2
  • 1715998-31-4
  • 3-(4-aMinophenyl)-3-oxo-1H,4H-2$l^{3},3$l^{6},4,5,9000000$l^{5},1-pyriMido[2,1-d]1$l^{3}-oxa-2$l^{6}-thia-3,5$l^{5}-diaza-6-argentacyclohexan-1-yliuM-4-id-9-yl
Copyright 2017 © ChemicalBook. All rights reserved