Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Structure
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate structure
CAS No.
1149-23-1
Chemical Name:
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
Synonyms
diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;DILUDINE;hantzschester;ethidine;1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER;1,4-dihydro-2,6-dimethyL;rr116;etidin;diethone;DIETHANE
CBNumber:
CB4757520
Molecular Formula:
C13H19NO4
Molecular Weight:
253.29
MDL Number:
MFCD00005951
MOL File:
1149-23-1.mol
MSDS File:
SDS
Last updated:2024-04-26 17:21:34
Request For Quotation

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Properties

Melting point 178-183 °C(lit.)
Boiling point 351.8±42.0 °C(Predicted)
Density 1.104±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Soluble in organic solvents.
pka 3.50±0.70(Predicted)
form Solid
color Yellow
λmax 374nm(EtOH)(lit.)
InChI InChI=1S/C13H19NO4/c1-5-17-12(15)10-7-11(13(16)18-6-2)9(4)14-8(10)3/h14H,5-7H2,1-4H3
InChIKey LJXTYJXBORAIHX-UHFFFAOYSA-N
SMILES C1(C)NC(C)=C(C(OCC)=O)CC=1C(OCC)=O
CAS DataBase Reference 1149-23-1(CAS DataBase Reference)
FDA UNII GWN6123BUG

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
WGK Germany  2
RTECS  US7970100
HS Code  29333990
Toxicity LD50 oral in dog: > 12gm/kg
NFPA 704
1
2 0

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate price More Price(50)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 120227 Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate 95% 1149-23-1 1G $73.8 2024-03-01 Buy
Sigma-Aldrich 120227 Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate 95% 1149-23-1 10G $455 2024-03-01 Buy
Sigma-Aldrich 120227 Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate 95% 1149-23-1 50G $1870 2024-03-01 Buy
TCI Chemical D3775 Diethyl 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate >98.0%(HPLC)(N) 1149-23-1 5g $24 2024-03-01 Buy
TCI Chemical D3775 Diethyl 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate >98.0%(HPLC)(N) 1149-23-1 25g $59 2024-03-01 Buy
Product number Packaging Price Buy
120227 1G $73.8 Buy
120227 10G $455 Buy
120227 50G $1870 Buy
D3775 5g $24 Buy
D3775 25g $59 Buy

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Chemical Properties,Uses,Production

Chemical Properties

Light green solid

Uses

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate is a hydrogen source in conjugate reduction and organocatalytic reductive amination. It is used as a hydrogen source in organocatalytic reductive amination and conjugate reduction.

Uses

3,5-Dicarboethoxy-2,6-dimethyl-1,4-dihydropyridine is a dihydropyridine derivative that have been tested for antimicrobial activities.

Application

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate (DTP) was used to study the mechanism of electrochemical oxidation of DTP in ethanol/water solutions on a glassy carbon electrode.

Hazard

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Toxicology

rat LD50 intraperitoneal >16 gm/kg
mouse LD50 oral >32 gm/kg
mouse LD50 intraperitoneal >30 gm/kg
dog LD50 oral >12 gm/kg

Synthesis

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate is prepared by the reaction of formaldehyd and ethyl acetoacetate in the presence of an inert gas.
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate synthesis

Purification Methods

recrystallization from EtOH or flash chromatography with petroleum/ethyl acetate (7:3)

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Preparation Products And Raw materials

Raw materials

Ethanol Hexamethylenetetramine

Preparation Products

Benidipine Nicardipine Glutaraldehyde Imazosulfuron Nilvadipine
pyridine-2,3,5,6-tetracarboxylic acid

1of2

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Suppliers

Global( 281)Suppliers
Supplier Tel Email Country ProdList Advantage
shandong perfect biotechnology co.ltd
+86-53169958659; +8618596095638 sales@sdperfect.com China 294 58
Hebei Mojin Biotechnology Co., Ltd 		+8613288715578 sales@hbmojin.com China 12456 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 11013 58
hebei hongtan Biotechnology Co., Ltd 		+86-86-1913198-3935 +8617331935328 sales03@chemcn.cn China 951 58
Ouhuang Engineering Materials (Hubei) Co., Ltd 		+8617702722807 admin@hbouhuang.com China 2259 58
Henan Suikang Pharmaceutical Co.,Ltd. 		+8618239973690 sales@suikangpharm.com China 178 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Supplier Advantage
shandong perfect biotechnology co.ltd
58
Hebei Mojin Biotechnology Co., Ltd 		58
Zibo Hangyu Biotechnology Development Co., Ltd 		58
hebei hongtan Biotechnology Co., Ltd 		58
Ouhuang Engineering Materials (Hubei) Co., Ltd 		58
Henan Suikang Pharmaceutical Co.,Ltd. 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60

View Lastest Price from Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate pictures 2024-04-26 Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
1149-23-1
 US $0.00 / kg 25kg 99.0% 1tons Henan Suikang Pharmaceutical Co.,Ltd.
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate pictures 2024-04-26 Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
1149-23-1
 US $15.00-6.00 / kg 1kg 99% 300tons Hebei Dangtong Import and export Co LTD
Diloxanidefuroate pictures 2024-04-26 Diloxanidefuroate
1149-23-1
 US $50.00 / kg 1kg 99% 2000kg hebei hongtan Biotechnology Co., Ltd

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Spectrum

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate(1149-23-1)MSDiethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate(1149-23-1)1HNMRDiethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate(1149-23-1)IR1Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate(1149-23-1)IR2

1149-23-1(Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate)Related Search:

Dimethyl carbonate Dacthal Ethylene glycol diethyl ether Pyridine hydrobromide 2,6-Lutidine
Dimethyl phthalate Dimethyl sulfate N,N-Dimethylformamide Dimethyl fumarate Quinolinic acid
Dimethyl sulfoxide Dimethyl disulfide 2,5-PYRIDINEDICARBOXYLIC ACID Mefenpyr-diethyl Diethyl oxalate
Diethyl malonate Dimethyl ether ETHANE

1of4

DIETHYL 2,6-DIMETHYL-1,4-DIHYDRO-3,5-PYRIDINEDICARBOXYLATE DIETHYL 2,6-DIMETHYL-1,4-DIHYDROPYRIDINEDICARBOXYLATE DIETHYL 1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLATE AURORA 4780 3,5-DICARBETHOXY-2,6-DIMETHYL-1,4-DIHYDROPYRIDINE 3,5-BIS(CARBOETHOXY)-2,6-DIMETHYL-1,4-DIHYDROPYRIDINE 2,6-DIMETHYL-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID DIETHYL ESTER 2,6-dimethyl-3,5-diethoxycarbonyl-1,4-dihydropyridine RARECHEM AQ NN 0171 5-pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-diethylester diethone etidin hantzsch’sdihydropyridine rr116 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid Diethyl Ester Hantzsch Ester 1,4-diethyl-2,6-diMethyl-1,4-dihydropyridine-3,5-dicarboxylate 3,5-Dicarboethoxy-2,6-dimethyl-1,4-dihydropyridine Diethyl 1,4-dihydro-2,6-diMethyl-3,5- pyridinedicarboxylat Diethyl 1,4-dihydro-2,6-diMethyl-3,5-pyridinedicarboxylate, 98%, 98% Diethyl1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate,98% DIETHYL1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLATE(DILUDIN) diethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate Dihydropyridinum Dihydropyride 2,6-Dimethyl-3.5-Diethylester-1.4-Diludine DILOXANIDEFUROATE DIETHANE Diethyl-1,4-dihydro-2,6-diMethyl-3,5-pyridine carboxylate 1,4-Dihydro-2,6-dimethylpyridine-3,5-dicarboxylic acid diethyl ester 1.4-dihydro-2.6-dimethyl-3.5-pyridinedicarboxylate 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-, 3,5-diethyl ester Diethyl 1,4-dihydro-3,5-pyridinecarboxylate, 95% Diethyl 1,4-dihydro- Lilium pumilum DC. Two hydropyridine 3,5-diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate Dihy**yridine 1,4-diethyl-2,6-dimethyl-4H-pyridine-3,5-dicarboxylate Diethyl-1,4-dihydro-2,6-dimethylpyridin-3,5-dicarboxylat Diethyl1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate> -3,5-pyridinedicarboxyL Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate USP/EP/BP 4-dihydro-2 5-pyridinedicarboxylate 6-dimethyl-3 Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxy Feed Medication Additives Diethyl 1,4-dihydro-3,5-pyridinecarboxylate, 95%, Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarbox DILUDINE 1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER ethidine hantzschester diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 1,4-dihydro-2,6-dimethyL Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarbo Aminocaproic Acid Impurity 16 1,4 Dihydro, 3,5,di-carboethoxy 2,6 dimethyl pyridine