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Description References
LACCASE structure
Chemical Name:
LACC;Sp 504;LACCASE;LACCASE T;LACCASE AB;LACCASE CV;EC;Laccase 001;Laccase 002;Laccase 003
Molecular Formula:
Formula Weight:
MOL File:

LACCASE Properties

storage temp. 
slightly beige
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn
Risk Statements  42
Safety Statements  23-45-24/25
WGK Germany  1
HS Code  35079090
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger P261, P285, P304+P341, P342+P311,P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P284 Wear respiratory protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

LACCASE price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 38429 Laccase from Trametes versicolor powder, light brown, ≥0.5 U/mg 80498-15-3 1g $102 2018-11-13 Buy
Sigma-Aldrich 38429 Laccase from Trametes versicolor powder, light brown, ≥0.5 U/mg 80498-15-3 10g $646 2018-11-13 Buy
Sigma-Aldrich 40452 Laccase from Agaricus bisporus powder, deep brown, ≥4 U/mg 80498-15-3 1g $679 2018-11-23 Buy
Sigma-Aldrich SAE0050 Laccase from Trametes versicolor 80498-15-3 50ml $76.2 2018-11-13 Buy
Sigma-Aldrich L2157 Laccase from Rhus vernicifera crude acetone powder, ≥50 units/mg solid 80498-15-3 10ku $139 2018-11-13 Buy

LACCASE Chemical Properties,Uses,Production


Laccase is a kind of copper-containing oxidase existing in many kinds of plants, fungi and microbes. It mainly takes effect on phenol-like compounds including phenols, polyphenols and anilines, performing one-electron oxidation. It is capable of catalyzing the ring cleavage reaction of aromatic compounds. In industry, laccase can be paired with an electron mediator to facilitate electron transfer to a solid electrode wire. It can also be applied to textile dyeing/textile finishing, wine cork making, teeth whitening with many other industrial, environmental, diagnostic, and synthetic uses. In food industry, laccase can be used to remove the polyphenols as well as oxygen that remain in the beer to increase the storage life of beer. Laccase can also be used in fruit juices to delay the oxidation of polyphenols and stabilize the juice.



Laccases are multicopper-oxidases (benzenediol:oxygen oxidoreductase, EC that are able to oxidize phenolic substrates (e.g. 2,6-dimethoxy-phenol), aromatic amines (e.g. 1-hydroxybenzotriazole), or polycyclic aromatic hydrocarbons (e.g. anthracene) . The oxidation of the substrate occurs via a oneelectron reduction and is accompanied by a reduction of molecular oxygen to water.
Most laccases are of fungal origin, but they also occur in bacteria, insects, and plants. Due to the broad substrate range of laccases, their possible industrial usage is widespread. Nevertheless, only few applications have been commercialized up to now, mostly in the textile industry. In the food and feed sector, laccases have been evaluated for different applications, such as the stabilization of beverages, the reduction of off-flavors, the improvement of wheat dough, and the usage of laccases as biosensors in the food processing industry. Off-flavors in wine may occur due to microbial conversion of phenolic compounds present in the wine itself or in the cork stoppers. In a commercial product from Novozymes called Suberase, laccase is used for polymerization of phenolic compounds in the cork, which act as precursors for malodors, such as pentachlorophenol or 2,4,6-trichloroanisol.
In apple juice, addition of laccase reduced the amount of the phenolic offflavors 2,6-dibromophenol, guaiacol, and a-terpineol. Several studies used laccases to increase the stability of apple juices by polymerization of phenols and their subsequent removal by ultrafiltration methods. A positive side effect is the decrease of molecular oxygen in the juice due to its consumption by laccases. Nevertheless, desired phenols might also be oxidized; thus, the sensory attributes and nutritional value might be altered.
The polymerization reactions catalyzed by laccases can also be used to improve the shade of food, such as the coloration of tea-based products. In the bakery industry, laccase might be used together with proteases or xylanases to improve the dough quality. It was proposed that laccases oxidize ferulic acid attached to the arabinoxylan present in cereal flour. The obtained phenolic radicals can undergo a nonenzymatic reaction, resulting in cross-linked feruloylated arabinoxylans. In oat flour-based bread, the usage of laccase increased the loaf-specific volume and decreased the crumb hardness. Contradictory, in another study, laccase alone decreased the specific volume and increased the crumb hardness. A combined usage of laccase with xylanase improved again the oat flour bread properties.

Biotechnological Applications

Lee et al. isolated and identified an extracellular laccase-producing strain of Y. lipolytica from soil. Extracellular laccase (YlLac) was purified by anionexchange and gel filtration chromatography. YlLac is a monomeric glycoprotein with 14 % carbohydrate content and a molecular weight of 67 kDa. It showed a higher catalytic efficiency toward 2,20-Azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (kcat/Km = 19.3 s-1 lM-1) and 2,6-dimethoxyphenol (kcat/Km = 13 s-1 lM-1) than any other reported laccases. This enzyme was able to oxidize phenolic compounds of pretreated rice straw. The use of YlLac for the removal of cellulase inhibitory compounds from biomass slurries is a promising approach for improving the efficiency of biorefineries (Lee et al. 2012).

LACCASE Preparation Products And Raw materials

Raw materials

Preparation Products

LACCASE Suppliers

Global( 70)Suppliers
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Haihang Industry Co.,Ltd
+86 531 8582 1093 CHINA 8260 58
Hubei xin bonus chemical co. LTD
027-59338440 CHINA 23049 58
BOC Sciences
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J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
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XiaoGan ShenYuan ChemPharm co,ltd Tell:86-712-2580635 Mobile:15527768850 . 15527768836
86-712-2580625 QQ:1791901229 China 9078 52
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 China 14460 57
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123
86-21-63290778 86-21-63218885 China 9847 79
BOC Sciences United States 10507 65
ShangHai YuanYe Biotechnology Co., Ltd. 021-61312847 qq:2797782341
021-55068248 China 7215 60
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611
+86 21 50676805 China 9920 58

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