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N,N',N''-TRIACETYLCHITOTRIOSE

N,N',N''-TRIACETYLCHITOTRIOSE
N,N',N''-TRIACETYLCHITOTRIOSE structure
CAS No.
38864-21-0
Chemical Name:
N,N',N''-TRIACETYLCHITOTRIOSE
Synonyms
CHITOTRIOSE;[(GlcNAc)3];N-acetylated Chitotriose;Tri(N-acetylglucosaMine);CHITOTRIOSE, TRI-N-ACETYL;N-AcetylglucosaMine TriMer;WZZVUHWLNMNWLW-RSGPGLJDSA-N;GLCNAC1-B-4GLCNAC1-B-4GLCNAC;N,N',N'-TRIACETYLCHITOTRIOSE;N,N',N''-TRIACETYLCHITOTRIOSE
CBNumber:
CB4774136
Molecular Formula:
C24H41N3O16
Formula Weight:
627.59
MOL File:
38864-21-0.mol

N,N',N''-TRIACETYLCHITOTRIOSE Properties

Melting point:
271-272°C dec.
Boiling point:
1146.9±65.0 °C(Predicted)
Density 
1.54±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
pka
12.72±0.70(Predicted)
BRN 
75249
SAFETY
  • Risk and Safety Statements
Safety Statements  24/25
WGK Germany  3
10-21
HS Code  29329990

N,N',N''-TRIACETYLCHITOTRIOSE price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T2144 N,N′,N′′-Triacetylchitotriose ≥93% (HPLC) 38864-21-0 10mg $238 2019-12-02 Buy
Sigma-Aldrich T2144 N,N′,N′′-Triacetylchitotriose ≥93% (HPLC) 38864-21-0 50mg $947 2019-12-02 Buy
TCI Chemical T2912 N,N',N''-Triacetylchitotriose >98.0%(HPLC) 38864-21-0 20mg $363 2019-12-02 Buy
Cayman Chemical 20759 N,N',N''-Triacetylchitotriose ≥95% 38864-21-0 1mg $40 2018-11-19 Buy
Cayman Chemical 20759 N,N',N''-Triacetylchitotriose ≥95% 38864-21-0 5mg $100 2018-11-19 Buy

N,N',N''-TRIACETYLCHITOTRIOSE Chemical Properties,Uses,Production

Chemical Properties

Off-White Crystalline Solid

Uses

N,N',N''-Triacetylchitotriose is a triose oligosaccharide derived from chitin, consisting of three N-acetylglucosamine units. It has been shown to scavenge reactive oxygen species and to protect DNA from oxidative damage.

Reactions

The hydrolytic activity of lysozyme towards 4-methylumbelliferyl tetra-N-acetyl-β-chitotetraoside (4-MU-(GlcNAc)4) was little affected by ionic strength, though the activity of lysozyme towards cell suspension of Micrococcus lysodeikticus varied markedly with ionic strength. About 40-60percent of lysozyme activity with 4-MU-(GlcNAc)4 as a substrate was inhibited by 0.1 mM N,N',N''-triacetylchitotriose ((GlcNAc)3), but the lytic activity of lysozyme towards M. lysodeikticus was little affected. The kinetics of hydrolysis of 4-MU-(GlcNAc)4 by hen eggwhite (HEW) lysozyme and human placental (HP) lysozyme and the inhibition of this hydrolysis by (GlcNAc)3 were investigated. The K(s) values for 4-MU-(GlcNAc)4 of HEW- and HP-lysozymes were 19.7 and 27.9 μM, respectively, and the V(max) values were 0.124 and 0.0833 nmol/min/mg, respectively. The k values of both enzymes were very low, implying a poor orientation of the scissile bond in the substrate molecule with respect to the active site of lysozyme. (GlcNAc)3 inhibited lysozyme with hyperbolic mixed-type inhibition. The inhibition reduced V(max) values of both lysozymes. The K(s) value of HEW-lysozyme was increased by the addition of the inhibitory whereas the K(s) value of HP-lysozyme was decreased. The K(i) value was 29.6 μm for HEW-lysozyme and 106 μM for HP-lysozyme.
  1. Hydrolysis of 4-methylumbelliferyl tetra-N-acetyl-β-chitotetraoside by lysozyme and its inhibition by N,N',N''-triacetylchitotriose
  2. Tanimoto; Fukuda; Kawamura - Chemical and Pharmaceutical Bulletin, 1984, vol. 32, # 9, p. 3607 - 361

N,N',N''-TRIACETYLCHITOTRIOSE Preparation Products And Raw materials

Raw materials

Preparation Products


N,N',N''-TRIACETYLCHITOTRIOSE Suppliers

Global( 56)Suppliers
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Qingdio BZ Oligo Biotech Co., Ltd.
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