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GALANTHAMINONE

CAS No.
510-77-0
Chemical Name:
GALANTHAMINONE
Synonyms
Narwedine;(4aS;8aS)-;Narwedin);-Narwedine;(-)-Narwedine;Galantaminone;GALANTHAMINONE;(-)-Narwedine 99.8% min;GALANTHAMINONE Impurity
CBNumber:
CB4774651
Molecular Formula:
C17H19NO3
Molecular Weight:
285.34
MDL Number:
MFCD08063719
MOL File:
510-77-0.mol
Last updated:2024-04-19 20:05:26

GALANTHAMINONE Properties

Melting point 175-180°C (dec.)
Boiling point 397.4±42.0 °C(Predicted)
Density 1.28±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility DMSO : 10 mg/mL (35.05 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form Cryst.
pka 7.84±0.20(Predicted)
FDA UNII 38CR9WB857

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H331-H301
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501-P261-P271-P304+P340-P311-P321-P403+P233-P405-P501

GALANTHAMINONE price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC G188550 Galanthaminone 510-77-0 2mg $120 2021-12-16 Buy
TRC G188550 Galanthaminone 510-77-0 10mg $270 2021-12-16 Buy
TRC G188550 Galanthaminone 510-77-0 50mg $1100 2021-12-16 Buy
AK Scientific 9478AL Galanthaminone 510-77-0 25mg $1298 2021-12-16 Buy
Biosynth Carbosynth FG23641 Galanthaminone 510-77-0 50mg $1550 2021-12-16 Buy
Product number Packaging Price Buy
G188550 2mg $120 Buy
G188550 10mg $270 Buy
G188550 50mg $1100 Buy
9478AL 25mg $1298 Buy
FG23641 50mg $1550 Buy

GALANTHAMINONE Chemical Properties,Uses,Production

Description

This alkaloid occurs in several families of the Amaryllidaceae and is obtained as colourless prisms when crystallized from Me2CO. It is dextrorotatory with [α]25D + 100° (c 0.2, CHC13). It forms a crystalline picrate, m.p. 123°C; a methiodide, m.p. 195-6°C and a semicarbazone, indicative of a keto group, m.p. 240-1 °c (dec.).

Chemical Properties

White to Off-White

Uses

A metabolite of Galanthamine, a selective acetylcholinesterase inhibitor

Uses

Narwedine is the biogenetic precursor of galanthamine, has been studied as a respiratory stimulator. It increases the amplitude and decreases the frequency of cardiac contractions and would therefore be of value in reducing blood loss during surgery. It also inhibits the action of narcotics and hypnotics, and increases the analgesic effect of morphine as well as the pharmacological effects of caffeine, carbazole, arecoline, and nicotine.

Definition

ChEBI: Narwedine is a benzazepine.

target

AChR | IL Receptor

References

Boit, Dapke, Beitner., Chem. Ber., 90,2197 (1957)

GALANTHAMINONE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 149)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 sales@dolonchem.com CHINA 2972 58
Xi'an Kono chem co., Ltd.,
029-86107037 13289246953 info@konochemical.com China 2995 58
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14336 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Antai Fine Chemical Technology Co.,Limited
18503026267 info@antaichem.com CHINA 9641 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17367 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29474 58
Finetech Industry Limited
+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9571 58

View Lastest Price from GALANTHAMINONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
GALANTHAMINONE pictures 2024-04-19 GALANTHAMINONE
510-77-0
US $35.00-1.10 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
GALANTHAMINONE USP/EP/BP pictures 2021-07-28 GALANTHAMINONE USP/EP/BP
510-77-0
US $1.10 / g 1g 99.9% 100 Tons min Dideu Industries Group Limited
GALANTHAMINONE pictures 2020-01-08 GALANTHAMINONE
510-77-0
US $2.00 / KG 1g 98%MIN ASK Career Henan Chemical Co
  • GALANTHAMINONE pictures
  • GALANTHAMINONE
    510-77-0
  • US $35.00-1.10 / kg
  • 99%
  • Henan Fengda Chemical Co., Ltd

GALANTHAMINONE Spectrum

GALANTHAMINONE (4aS 8aS)- (4aS,8aS)-4a,5,9,10,11,12-Hexahydro-3-Methoxy-11-Methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one GalantaMine interMediate ((-)-Narwedine) GalantaMinone (GalantaMine IMpurity A) 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-one,4a,5,9,10,11,12-hexahydro-3-Methoxy-11-Methyl-, (4aS,8aS)- Galanthaminone Narwedine Galantamine Hydrobromide Lycoremine (4AS,8aS)-3-methoxy-11-methyl-9,10,11,12-tetrahydro-4aH-benzo[2,3]benzofuro[4,3-cd]azepin-6(5H Galantamine EP impurity A -F Narwedin) Galantamine EP impurity A N6-p-Methoxyphenyladenosin (-)-Narwedine 99.8% min Galantamine Impurity 1(Galantamine EP Impurity A) (-)-Narwedine Galnthaminone Narwedin Galantamine EP Impurity A (Galantaminone) (-)-Narwedine Galantaminone GALANTHAMINONE USP/EP/BP Galantamine hydrobromide EP Impurity A (4AS,8aS)-3-methoxy-11-methyl-4a,5,9,10,11,12-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepin-6-one Narwedine (4aS,8aS)-3-methoxy-11-methyl-4a,5,9,10,11,12-hexahydro-6H-[1]benzofuro[3a,3,2-ef][2]benzazepin-6-one (narwedine) Narwedine (6CI, 7CI, 8CI) -Narwedine (-)-Narwedine Galnthaminone Narwedin GALANTHAMINONE Impurity 510-77-0 19453 1953/4/4 raw materials Various Metabolites and Impurities Heterocycles Intermediates & Fine Chemicals Metabolites Pharmaceuticals