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4-BROMOPYRIDINE-2-CARBALDEHYDE

4-BROMOPYRIDINE-2-CARBALDEHYDE structure

CAS No.: 131747-63-2

Chemical Name:: 4-BROMOPYRIDINE-2-CARBALDEHYDE

Synonyms: 4-BROMOPICOLINALDEHYDE;4-Bromopyridine-2-carbaL;4-broMopyridin-2-carbaldehyde;4-BROMOPYRIDINE-2-CARBALDEHYD;4-BROMO-2-PYRIDINECARBALDEHYDE;4-BROMOPYRIDINE-2-CARBALDEHYDE;2-Pyridinecarboxaldehyde,4-broMo;4-broMo-2-pyridinecarboxaldehyde;4-Bromopyridine 2-carboxaldehyde;4-BROMOPYRIDINE-2-CARBALDEHYDE 131747-63-2

CBNumber:: CB4789684

Molecular Formula:: C6H4BrNO

Molecular Weight:: 186.01

MDL Number:: MFCD08690697

MOL File:: 131747-63-2.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:45

Product description	Number	Pack Size	Price
4-Bromopyridine-2-carboxaldehyde	B686135	1g	$140
4-Bromopyridine-2-carboxaldehyde	B686135	10g	$690
4-Bromopicolinaldehyde	FB142654	25g	$937.5
4-BROMOPICOLINALDEHYDE 95.00%	HCH0036518	1G	$985
4-BROMOPICOLINALDEHYDE 95.00%	HCH0036518	5G	$1476.09
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4-BROMOPYRIDINE-2-CARBALDEHYDE Properties

Boiling point	244.0±20.0 °C(Predicted)
Density	1.683±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	Chloroform (Slightly), DMSO (Sparingly)
form	solid
pka	1.78±0.10(Predicted)
color	Off-white to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H332-H335
Precautionary statements	P261-P280-P305+P351+P338
HS Code	2933399990

4-BROMOPYRIDINE-2-CARBALDEHYDE price More Price(39)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	B686135	4-Bromopyridine-2-carboxaldehyde	131747-63-2	1g	$140	2021-12-16	Buy
TRC	B686135	4-Bromopyridine-2-carboxaldehyde	131747-63-2	10g	$690	2021-12-16	Buy
Biosynth Carbosynth	FB142654	4-Bromopicolinaldehyde	131747-63-2	25g	$937.5	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0036518	4-BROMOPICOLINALDEHYDE 95.00%	131747-63-2	1G	$985	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0036518	4-BROMOPICOLINALDEHYDE 95.00%	131747-63-2	5G	$1476.09	2021-12-16	Buy

Product number	Packaging	Price	Buy
B686135	1g	$140	Buy
B686135	10g	$690	Buy
FB142654	25g	$937.5	Buy
HCH0036518	1G	$985	Buy
HCH0036518	5G	$1476.09	Buy

4-BROMOPYRIDINE-2-CARBALDEHYDE Chemical Properties,Uses,Production

Uses

4-Bromopyridine-2-carboxaldehyde is a reagent used to synthesize Curcumin (C838500) analogues. It can also be used to prepare 1,4-dihydropyridine calcium antagonists.

Synthesis

131747-45-0

131747-63-2

General procedure for the synthesis of 4-bromopyridine-2-carboxaldehyde from 2-hydroxymethyl-4-bromopyridine: 3L of dichloromethane (DCM) was added to a 5L three-necked flask under nitrogen protection, and cooled to -60 °C. During the cooling process, 240 g of oxalyl chloride was added slowly and dropwise. Maintaining the reaction temperature at -60 °C, 295.6 g of dimethyl sulfoxide (DMSO) was added dropwise to the reaction system and held for 30 min after the dropwise addition. Subsequently, 237.5 g of 2-hydroxymethyl-4-bromopyridine (Cpd 3) was slowly added dropwise at -60 °C and the reaction was continued at -65 °C for 1 hour. At this temperature, 3.5 equivalents of triethylamine (TEA) was added, and the reaction solution was allowed to stand before the progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the target product 4-bromopyridine-2-carboxaldehyde (Compound 4) was purified by column chromatography to give 177.2 g in 75% yield.

References

[1] Patent: US2010/125082, 2010, A1. Location in patent: Page/Page column 24
[2] Tetrahedron, 1997, vol. 53, # 24, p. 8257 - 8268
[3] Patent: CN108516953, 2018, A. Location in patent: Paragraph 0067-0068; 0074-0075; 0076-0083
[4] Chemical and Pharmaceutical Bulletin, 1990, vol. 38, # 9, p. 2446 - 2458
[5] MedChemComm, 2015, vol. 6, # 7, p. 1252 - 1259

4-BROMOPYRIDINE-2-CARBALDEHYDE synthesis

Synthesis of 4-BROMOPYRIDINE-2-CARBALDEHYDE from 4-Bromo-2-pyridinemethanol

4-BROMOPYRIDINE-2-CARBALDEHYDE Preparation Products And Raw materials

Raw materials

(4-Bromopyridin-2-yl)methyl acetate 4-Nitropicolinaldehyde CHEMPACIFIC 38139 4-Bromo-N-methoxy-N-methylpicolinamide 4-bromo-2-methylpyridine 1-oxide

4-Bromo-2-pyridinemethanol 2-Picoline-N-oxide 2-Methyl-4-nitropyridine 4-Nitro-2-picoline N-oxide Phenyl chloroformate

4-Bromopyridine-2-carboxylic acid

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Preparation Products

4-Bromo-2-methylpyridine

4-BROMOPYRIDINE-2-CARBALDEHYDE Suppliers

Global( 175)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21612	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29798	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	20284	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Hubei Jusheng Technology Co.,Ltd.	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
ANHUI WITOP BIOTECH CO., LTD	58
Dideu Industries Group Limited	58

View Lastest Price from 4-BROMOPYRIDINE-2-CARBALDEHYDE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-18	4-BROMOPYRIDINE-2-CARBALDEHYDE 131747-63-2	US $1.10 / g	1g	99.00%	100 Tons min	Dideu Industries Group Limited
2020-05-13	4-Bromopicolinaldehyde 131747-63-2	US $0.00-0.00 / Kg	1KG	99.0%	500 MT	Shaanxi Dideu Medichem Co. Ltd
2019-12-23	4-BROMOPYRIDINE-2-CARBALDEHYDE 131747-63-2	US $1.00 / KG	1KG	99%	200kg	Career Henan Chemical Co

4-BROMOPYRIDINE-2-CARBALDEHYDE
131747-63-2
US $1.10 / g
99.00%
Dideu Industries Group Limited

4-Bromopicolinaldehyde
131747-63-2
US $0.00-0.00 / Kg
99.0%
Shaanxi Dideu Medichem Co. Ltd

4-BROMOPYRIDINE-2-CARBALDEHYDE
131747-63-2
US $1.00 / KG
99%
Career Henan Chemical Co

4-BROMOPYRIDINE-2-CARBALDEHYDE Spectrum

4-BROMOPYRIDINE-2-CARBALDEHYDE(131747-63-2)¹HNMR

131747-63-2(4-BROMOPYRIDINE-2-CARBALDEHYDE)Related Search:

4-BROMOPYRIDINE-2-CARBALDEHYDE 4-BROMOPYRIDINE-2,6-DICARBOXYLIC ACID 4-BROMO-PYRIDINE-2,6-DICARBOXYLIC ACID DIAMIDE 4-BROMO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER 4-Bromo-pyridine-2-carboxylic acid ethyl ester

4-Bromopyridine-2-carboxylic acid 4-BROMOQUINOLINE-2-CARBOXYLIC ACID Dimethyl 2-bromo-2,6-pyridinedicarboxylate 4-BROMOQINOLINE-2-CARBOXALDEHYDE 4-BROMO-6-METHYL-PYRIDINE-2-CARBALDEHYDE

Diethyl 4-bromopyridine-2,6-dicarboxylate 4-Bromo-2,6-diformylpyridine 1-(4-BROMOPYRIDIN-2-YL)-2,2,2-TRIFLUOROETHANONE 2-AMINO-4-BROMO-6-CARBOXYPYRIDINE METHYL ESTER 4-BROMO-6-METHYL-PYRIDINE-2-CARBOXYLIC ACID

4-BROMO-3-METHYL-PYRIDINE-2-CARBALDEHYDE 4-BROMO-6-METHYL-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER 4-BROMO-6-METHYLPYRIDINE-2-CARBOXAMIDE

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4-Bromopyridine 2-carboxaldehyde 4-BROMOPYRIDINE-2-CARBALDEHYDE 4-broMopyridin-2-carbaldehyde 4-broMo-2-pyridinecarboxaldehyde 2-Pyridinecarboxaldehyde,4-broMo 4-Bromopyridine-2-carbaL 4-BROMO-2-PYRIDINECARBALDEHYDE 4-BROMOPYRIDINE-2-CARBALDEHYDE ISO 9001：2015 REACH 4-BROMOPYRIDINE-2-CARBALDEHYDE 131747-63-2 4-BROMOPICOLINALDEHYDE 4-BROMOPYRIDINE-2-CARBALDEHYD 131747-63-2 Pyridines Heterocycle-Pyridine series