ChemicalBook >> CAS DataBase List >>COLIVELIN

COLIVELIN

COLIVELIN structure

CAS No.: 867021-83-8

Chemical Name:: COLIVELIN

Synonyms: COLIVELIN;Colivelin (human);SALLRSIPAPAGASRLLLLTGEIDLP;SER-ALA-LEU-LEU-ARG-SER-ILE-PRO-ALA-PRO-ALA-GLY-ALA-SER-ARG-LEU-LEU-LEU-LEU-THR-GLY-GLU-ILE-ASP-LEU-PRO;H-SER-ALA-LEU-LEU-ARG-SER-ILE-PRO-ALA-PRO-ALA-GLY-ALA-SER-ARG-LEU-LEU-LEU-LEU-THR-GLY-GLU-ILE-ASP-LEU-PRO-OH;Amyloid-β,β-amyloid peptide,STAT,Colivelin,Inhibitor,inhibit,disease,Neuroprotectant,Abeta,ischemic,brain,neurological,alzheimer,injury;Colivelin trifluoroacetate salt H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH trifluoroacetate salt;L-Proline, L-seryl-L-alanyl-L-leucyl-L-leucyl-L-arginyl-L-seryl-L-isoleucyl-L-prolyl-L-alanyl-L-prolyl-L-alanylglycyl-L-alanyl-L-seryl-L-arginyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-threonylglycyl-L-α-glutamyl-L-isoleucyl-L-α-aspartyl-L-leucyl-

CBNumber:: CB4795124

Molecular Formula:: C119H206N32O35

Molecular Weight:: 2645.15

MDL Number:: MFCD08704663

MOL File:: 867021-83-8.mol

Last updated:2024-04-17 18:50:11

Request For Quotation

COLIVELIN Properties

Density	1.42±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	insoluble in DMSO; insoluble in EtOH; ≥15 mg/mL in H2O
form	solid
color	White
Water Solubility	Soluble to 1 mg/ml in 20% ethanol / water

COLIVELIN price More Price(15)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	24239	Colivelin ≥95%	867021-83-8	500μg	$242	2024-03-01	Buy
Cayman Chemical	24239	Colivelin ≥95%	867021-83-8	1mg	$364	2024-03-01	Buy
Tocris	3945	Colivelin	867021-83-8	500U	$314	2021-12-16	Buy
TRC	C641530	Colivelin	867021-83-8	5mg	$2475	2021-12-16	Buy
Usbiological	255021	Colivelin	867021-83-8	500ug	$573	2021-12-16	Buy

Product number	Packaging	Price	Buy
24239	500μg	$242	Buy
24239	1mg	$364	Buy
3945	500U	$314	Buy
C641530	5mg	$2475	Buy
255021	500ug	$573	Buy

COLIVELIN Chemical Properties,Uses,Production

Description

Colivelin is a potent synthetic peptide activator of STAT3 that has neuroprotective activity. It protects approximately 50 and 100% of mouse primary cortical neurons from cell death induced by amyloid β (1-43) (Aβ43) when used at concentrations of 10 and 100 fM, respectively. Colivelin protects against cell death induced by V642I-APP in a CaM kinase IV (CaMKIV) and STAT3-dependent manner. It increases STAT3 phosphorylation in vitro and in vivo, an effect that correlates with improvements in working memory. Colivelin (10 pmol every six days) rescues deficits in spatial working memory in a mouse model of Alzheimer’s disease induced by intracerebroventricular injection of Aβ25-35. It also improves motor performance and prolongs survival in a mouse model of amyotrophic lateral sclerosis (ALS).

Uses

Colivelin is a peptide that offers neuroprotective effects against Alzheimer''s Disease (AD). It is also an activator of STAT3, a transcription factor involved with the JAK2/STAT3 pathway. Aberration in this pathway is linked to the pathogenesis of AD. Neuroprotective product.

storage

Store at -20°C

COLIVELIN Preparation Products And Raw materials

Raw materials

Preparation Products

COLIVELIN Suppliers

Global( 93)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Kangcang new material Technology Co., LTD	+8619133911216	Jany1001@kangcang.com.cn	China	338	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19743	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
Hebei Miaoyin Technology Co.,Ltd	+86-17367732028 +86-17367732028	kathy@hbyinsheng.com	China	3582	58
Nanjing TGpeptide	+86-13347807150 +86-13347807150	support@tgpeptide.com	China	3279	58
Zhejiang Hangyu API Co., Ltd	+8617531972939	anna@api-made.com	China	2944	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58

Supplier	Advantage
Hebei Kangcang new material Technology Co., LTD	58
Shenzhen Nexconn Pharmatechs Ltd	58
career henan chemical co	58
BOC Sciences	58
Zhejiang J&C Biological Technology Co.,Limited	58
Chengdu Youngshe Chemical Co., Ltd.	58
Hebei Miaoyin Technology Co.,Ltd	58
Nanjing TGpeptide	58
Zhejiang Hangyu API Co., Ltd	58
LEAPCHEM CO., LTD.	58

View Lastest Price from COLIVELIN manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-04-24	Colivelin trifluoroacetate salt 867021-83-8	US $20.00-10.00 / kg	1kg	98%	20	Hebei Kangcang new material Technology Co., LTD
	2020-03-06	COLIVELIN 867021-83-8	US $1.00 / g	1g	≥98%	g/kg/Ton	Career Henan Chemical Co

Colivelin trifluoroacetate salt
867021-83-8
US $20.00-10.00 / kg
98%
Hebei Kangcang new material Technology Co., LTD

COLIVELIN
867021-83-8
US $1.00 / g
≥98%
Career Henan Chemical Co

COLIVELIN Spectrum

COLIVELIN(867021-83-8)MS

867021-83-8(COLIVELIN)Related Search:

Tetanus toxin (830-843) PYR-LEU-THR-PHE-THR-SER-SER-TRP-GLY-NH2 PACAP38 NEUROKININ A L-Leu-Leu-Leu

COLIVELIN

1of2

COLIVELIN H-SER-ALA-LEU-LEU-ARG-SER-ILE-PRO-ALA-PRO-ALA-GLY-ALA-SER-ARG-LEU-LEU-LEU-LEU-THR-GLY-GLU-ILE-ASP-LEU-PRO-OH Colivelin (human) SER-ALA-LEU-LEU-ARG-SER-ILE-PRO-ALA-PRO-ALA-GLY-ALA-SER-ARG-LEU-LEU-LEU-LEU-THR-GLY-GLU-ILE-ASP-LEU-PRO L-Proline, L-seryl-L-alanyl-L-leucyl-L-leucyl-L-arginyl-L-seryl-L-isoleucyl-L-prolyl-L-alanyl-L-prolyl-L-alanylglycyl-L-alanyl-L-seryl-L-arginyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-threonylglycyl-L-α-glutamyl-L-isoleucyl-L-α-aspartyl-L-leucyl- Colivelin trifluoroacetate salt H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH trifluoroacetate salt Amyloid-β,β-amyloid peptide,STAT,Colivelin,Inhibitor,inhibit,disease,Neuroprotectant,Abeta,ischemic,brain,neurological,alzheimer,injury SALLRSIPAPAGASRLLLLTGEIDLP 867021-83-8 C119H206N32O35 Amyloid beta-peptide and related