Crisaborole intermediate

CAS No.
1187230-70-1
Chemical Name:
Crisaborole intermediate
Synonyms
Crisaborole Impurity 34;5-(4-(aminomethyl)phenoxy)benzo[c][1,2]oxaborol-1(3H)-ol;Benzenemethanamine, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-;4-?[(1,?3-?Dihydro-?1-?hydroxy-?2,?1-?benzoxaborol-?5-?yl)?oxy]?-benzenemethanamine
CBNumber:
CB48131270
Molecular Formula:
C14H14BNO3
Molecular Weight:
255.08
MDL Number:
MOL File:
1187230-70-1.mol
Last updated:2022-12-21 16:56:50

Crisaborole intermediate Properties

Boiling point 417.2±55.0 °C(Predicted)
Density 1.28±0.1 g/cm3(Predicted)
pka 7.04±0.20(Predicted)
FDA UNII LLM3AN3HDP

Crisaborole intermediate Chemical Properties,Uses,Production

Uses

4-?[(1,?3-?Dihydro-?1-?hydroxy-?2,?1-?benzoxaborol-?5-?yl)?oxy]?-benzenemethanamine is used as a research tool in the assessment of its benzoxaborole moiety to serve as a hinge-binding scaffold for ROCK inhibition; playing a role in SMC relaxation in rat aorta and guinea pig trachea.

Crisaborole intermediate Preparation Products And Raw materials

Raw materials

Preparation Products

Crisaborole intermediate Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
Beijing Comparison Pharmaceutical Technology Co., Ltd 010-52878169 15701683040 sales@bjcomparison.com China 4673 58
ChemStrong Scientific Co.,Ltd 0755-66853366 13670046396 sales@chem-strong.com China 17982 56
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9911 50
Wuxi Helen Biotechnology Co., Ltd., 0510-85629785 18013409632 sales@reading-chemicals.com China 14092 58
BEIJING INNO-TECH PHARMIC TECHNOLOGY CO.,LTD 15011485209 China 145 58
Changzhou Xianglong Pharmaceutical Technology Co., LTD 18661161657 yaoxiangqiu2021@163.com China 10066 58
Shenzhen Qingtian Biotechnology Co, Ltd. 18823167005 18162969855 744288988@qq.com China 2645 58
Nantong Hanfang Biotechnology Co. , Ltd. 3674309880 hanfangpharma@126.com China 30968 58
5-(4-(aminomethyl)phenoxy)benzo[c][1,2]oxaborol-1(3H)-ol 4-?[(1,?3-?Dihydro-?1-?hydroxy-?2,?1-?benzoxaborol-?5-?yl)?oxy]?-benzenemethanamine Crisaborole Impurity 34 Benzenemethanamine, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]- 1187230-70-1