ChemicalBook >> CAS DataBase List >>Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)-
Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)-
- CAS No.
- 2416910-69-3
- Chemical Name:
- Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)-
- Synonyms
- SENP1-IN-1;Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)-
- CBNumber:
- CB48379610
- Molecular Formula:
- C35H58N2O4
- Molecular Weight:
- 570.86
- MDL Number:
- MOL File:
- 2416910-69-3.mol
Last updated:2024-07-02 08:55:09
Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)- Chemical Properties,Uses,Production
Biological Activity
SENP1-IN-1 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 29. SENP1-IN-1 is developed for tumor radiosensitivity enhancement[1]. SENP1-IN-1 may improve the sensitivity of tumor cells to irradiation[1].SENP1-IN-1 (0.7-20 μM; 72 hours)has cytotoxic for Hella cells with an IC50 of >20μM[1].
References
[1]. Li, Yiliang, et al. Preparation of ursolic acid derivatives useful as SENP1 inhibitors and tumor radiosensitizer. CN110627860A.
Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)- Preparation Products And Raw materials
Raw materials
Preparation Products
Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)- Suppliers
Global( 1)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd | 021-59167510 18117107507 | vip@med-life.cn | China | 4997 | 58 |
Supplier | Advantage |
---|---|
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd | 58 |
Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)-
SENP1-IN-1
2416910-69-3
C35H58N2O4