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Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)-

Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)- structure

CAS No.: 2416910-69-3

Chemical Name:: Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)-

Synonyms: SENP1-IN-1;Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)-

CBNumber:: CB48379610

Molecular Formula:: C35H58N2O4

Molecular Weight:: 570.86

MDL Number:

MOL File:: 2416910-69-3.mol

Last updated:2023-05-21 10:59:17

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Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)- Properties

Boiling point	705.8±60.0 °C(Predicted)
Density	1.12±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
pka	14.41±0.10(Predicted)

Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)- Chemical Properties,Uses,Production

Biological Activity

SENP1-IN-1 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 29. SENP1-IN-1 is developed for tumor radiosensitivity enhancement[1]. SENP1-IN-1 may improve the sensitivity of tumor cells to irradiation[1].SENP1-IN-1 (0.7-20 μM; 72 hours)has cytotoxic for Hella cells with an IC50 of >20μM[1].

References

[1]. Li, Yiliang, et al. Preparation of ursolic acid derivatives useful as SENP1 inhibitors and tumor radiosensitizer. CN110627860A.

Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)- Preparation Products And Raw materials

Raw materials

Preparation Products

Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)- Suppliers

Global( 1)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd	021-59167510 18117107507	vip@med-life.cn	China	5019	58

Supplier	Advantage
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd	58

Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)- SENP1-IN-1 2416910-69-3 C35H58N2O4