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Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)-

CAS No.
2416910-69-3
Chemical Name:
Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)-
Synonyms
SENP1-IN-1;Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)-
CBNumber:
CB48379610
Molecular Formula:
C35H58N2O4
Molecular Weight:
570.86
MDL Number:
MOL File:
2416910-69-3.mol
Last updated:2024-07-02 08:55:09

Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)- Properties

Boiling point 705.8±60.0 °C(Predicted)
Density 1.12±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
form Solid
pka 14.41±0.10(Predicted)
color White to off-white

Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)- Chemical Properties,Uses,Production

Biological Activity

SENP1-IN-1 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 29. SENP1-IN-1 is developed for tumor radiosensitivity enhancement[1]. SENP1-IN-1 may improve the sensitivity of tumor cells to irradiation[1].SENP1-IN-1 (0.7-20 μM; 72 hours)has cytotoxic for Hella cells with an IC50 of >20μM[1].

References

[1]. Li, Yiliang, et al. Preparation of ursolic acid derivatives useful as SENP1 inhibitors and tumor radiosensitizer. CN110627860A.

Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)- Preparation Products And Raw materials

Raw materials

Preparation Products

Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)- Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 021-59167510 18117107507 vip@med-life.cn China 4997 58
Supplier Advantage
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 58
Urs-12-en-28-amide, 3-hydroxy-N-[2-[(2-hydroxyethyl)methylamino]-2-oxoethyl]-, (3β)- SENP1-IN-1 2416910-69-3 C35H58N2O4