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Febuxostat

Indications and Usage Mechanisms of Action
Febuxostat
Febuxostat
CAS No.
144060-53-7
Chemical Name:
Febuxostat
Synonyms
FBX;Uloric;TMX 67;Tei-6720;Febuxosta;FEBUXOSTAT;FEBUXOSTAT API;Febuxostat IMP;Febuxostat, >=99%;Febuxostat Tablets
CBNumber:
CB4841564
Molecular Formula:
C16H16N2O3S
Formula Weight:
316.37
MOL File:
144060-53-7.mol

Febuxostat Properties

Melting point:
238-239°(dec.)
storage temp. 
Refrigerator
form 
powder
Merck 
14,3948
CAS DataBase Reference
144060-53-7(CAS DataBase Reference)

SAFETY

RTECS  XJ3675310

Febuxostat price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical F0847 Febuxostat >97.0%(HPLC)(T) 144060-53-7 1g $84 2018-11-22 Buy
TCI Chemical F0847 Febuxostat >97.0%(HPLC)(T) 144060-53-7 5g $272 2018-11-22 Buy
Cayman Chemical 14127 Febuxostat ≥98% 144060-53-7 10mg $86 2018-11-13 Buy
Cayman Chemical 14127 Febuxostat ≥98% 144060-53-7 5mg $45 2018-11-13 Buy
Cayman Chemical 14127 Febuxostat ≥98% 144060-53-7 25mg $203 2018-11-13 Buy

Febuxostat Chemical Properties,Uses,Production

Indications and Usage

Febuxostat is a new generation xanthine oxidase inhibitor developed by Tejin Co. (Japan,) used clinically for for long-term treatment of hyperuicemia (gout,) a new and highly effective non-purine selective inhibitor of xanthine oxidase. It is not recommended for gout patients without hyperuricemia.

Mechanisms of Action

The production of uric acid in the body is related to purine metabolism. In the last step of the production, hypoxanthine produces xanthine through the action of xanthine oxidoreductase (XOR), finally producing uric acid. Inhibiting the activity of this enzyme can effectively reduce the production of uric acid. Xanthine oxidase is the main enzyme promoting uric acid production. Through highly selective inhibition of oxidized and reduced xanthine oxidase, Febuxostat can reduce synthesis of uric acid, decreasing its concentration and effectively treating gout . Through liver metabolism, Xanthine oxidase does not rely on renal excretion, so patients with moderate to severe liver and kidney dysfunction do not need to reduce dosages. Febuxostat is a non-purine XOR inhibitor, so it is very safe.

Chemical Properties

Crystalline Solid

Uses

antihyperlipidemic

Uses

Xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.

Uses

Febuxostat is primarily indicated in conditions like Gout, Hyperuricemia

Febuxostat Preparation Products And Raw materials

Raw materials

Preparation Products


Febuxostat Suppliers

Global( 328)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Jinan Jianfeng Chemical Co., Ltd
15562555968
info@pharmachemm.com CHINA 617 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-0311-66562153 whatsapp +8615203118427
+86-0311-66562153 sales@crovellbio.com CHINA 416 50
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3217 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22049 58
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497 sales01@cooperate-pharm.com CHINA 1530 55
Hebei Jiangkai Trading Co., Ltd
0086-17197824289/17197824028
alice@hbjkai.com CHINA 277 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555
+86-021-57951555 jack.li@time-chemicals.com CHINA 1374 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
PI & PI BIOTECH INC.
020-81716320
020-81716319 Sales@pipitech.com CHINA 2548 55

View Lastest Price from Febuxostat manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-06-19 febuxostat
144060-53-7
US $1.00 / KG 10UG 99%+ 500kg Dalian Pinmai Biotechnology Co., Ltd
2018-08-20 Febuxostat
144060-53-7
US $1.00 / KG 1G 98% 100KG career henan chemical co
2018-07-26 Febuxostat
144060-53-7
US $100.00 / KG 1KG 98% 100KG career henan chemical co

144060-53-7(Febuxostat)Related Search:


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