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History Uses Production Reactions Toxicity
Nickel structure
Chemical Name:
Ni;NP 2;(1WT%);Nickel;Ni 270;Nichel;NI-5249P;raney ni;NI000525;NI000110
Molecular Formula:
Formula Weight:
MOL File:

Nickel Properties

Melting point:
212 °C (dec.)(lit.)
Boiling point:
2732 °C(lit.)
vapor density 
5.8 (vs air)
storage temp. 
Flammables area
White to gray-white
Specific Gravity
6.97 μΩ-cm, 20°C
Water Solubility 
It is insoluble in water.
air sensitive
Exposure limits
TLA-TWA (metal) 1 mg/m3 (ACGIH, MSHA, and OSHA); (soluble inorganic compounds) 0.1 mg(Ni)/m3 (ACGIH) 0.015 mg (Ni)/m3 (NIOSH); (insoluble inorganic compounds) 1 mg/m3 (ACGIH).
Stable in massive form. Powder is pyrophoric - can ignite spontaneously. May react violently with titanium, ammonium nitrate, potassium perchlorate, hydrazoic acid. Incompatible with acids, oxidizing agents, sulfur.
CAS DataBase Reference
7440-02-0(CAS DataBase Reference)
NIST Chemistry Reference
EPA Substance Registry System
  • Risk and Safety Statements
Signal word  Danger
Hazard statements  H301-H311-H315-H319-H332-H334-H335-H228-H350-H373-H413-H317-H351-H372-H412-H250
Precautionary statements  P273-P280-P314-P333+P313-P210-P302+P334-P422-P231-P260-P370+P378-P285-P302+P352-P305+P351+P338-P321-P405-P501a-P201-P261-P308+P313-P222-P422a
Hazard Codes  C,Xi,Xn,F,T
Risk Statements  34-50/53-43-40-10-17-52/53-48/23
Safety Statements  26-45-60-61-36-22-36/37-16-15-5-36/37/39-43-28
RIDADR  UN 1493 5.1/PG 2
WGK Germany  3
RTECS  VW4725000
HazardClass  4.1
PackingGroup  II
HS Code  38151100

NFPA 704

Diamond Hazard Value Description
2 1
Health   2 Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine)
Flammability   4 Will rapidly or completely vaporize at normal atmospheric pressure and temperature, or is readily dispersed in air and will burn readily. Includes pyrophoric substances. Flash point below room temperature at 22.8 °C (73 °F). (e.g. acetylene, propane, hydrogen gas)
Instability   1 Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene)

(NFPA, 2010)

Nickel price More Price(365)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 203904 Nickel powder, <150 μm, 99.99% trace metals basis 7440-02-0 25g $46.9 2018-11-13 Buy
Sigma-Aldrich 203904 Nickel ≥99%, FG 7440-02-0 100g $115 2018-11-13 Buy
TCI Chemical S0487 Skeletal Nickel Catalyst slurry in Water [Active catalyst for Hydrogenation] 7440-02-0 50g $33 2018-11-22 Buy
Alfa Aesar 000223 Nickel wire, 0.63mm (0.025in) dia, 99.7% (metals basis) 7440-02-0 25m $97.1 2018-11-16 Buy
Alfa Aesar 000223 Nickel wire, 0.63mm (0.025in) dia, 99.7% (metals basis) 7440-02-0 100m $252 2018-11-16 Buy

Nickel Chemical Properties,Uses,Production


Nickel was isolated first and recognized as an element by Cronstedt in 1751. The metal was derived in pure form by Richter in 1804. The metal takes its name from two German words ‘Nickel’ and ‘kupfernickel’, which mean Old Nick’s (or Satan) and Old Nick’s copper, respectively.
The abundance of nickel in the earth’s crust is only 84 mg/kg, the 24th most abundant element. It is found in most meteorites, particularly in the iron meteorites or siderites, alloyed with iron. Its average concentration in seawater is 0.56 μg/mL. Nickel is one of the major components of the earth’s core, comprising about 7%.
The most common nickel ores are pentlandite, (Ni,Fe)9S16, limonite, (Fe,Ni)O(OH)•nH2O, and garnierite, (Ni,Mg)6Si4O10(OH)8. Other ores that are of rare occurrence are the sulfide ores, millerite, NiS, polydymite Ni3S4 and siegenite, (Co,Ni)3S4; the arsenide ores niccolite, NiAs, gersdorffite, NiAsS, and annabergite, Ni3As2O8•8H2O; and the antimonide ore, NiSb.


The most important applications of nickel metal involve its use in numerous alloys. Such alloys are used to construct various equipment, reaction vessels, plumbing parts, missile, and aerospace components. Such nickel-based alloys include Monel, Inconel, Hastelloy, Nichrome, Duranickel, Udinet, Incoloy and many other alloys under various other trade names. The metal itself has some major uses. Nickel anodes are used for nickel plating of many base metals to enhance their resistance to corrosion. Nickel-plated metals are used in various equipment, machine parts, printing plates, and many household items such as scissors, keys, clips, pins, and decorative pieces. Nickel powder is used as porous electrodes in storage batteries and fuel cells.
Another major industrial use of nickel is in catalysis. Nickel and raney nickel are used in catalytic hydrogenation or dehydrogenation of organic compounds including olefins, fats, and oils.


Nickel usually is recovered from its sulfide ore, pentlandite (Ni,Fe)9S16. Although laterite type oxide ores sometimes are used as starting materials, pentlandite is used in many commercial operations. Pentlandite often is found in nature associated with other sulfide minerals, such as pyrrhotite, Fe7S8,and chalcopyrite, CuFeS2.
The ores are crushed and powdered. Sulfides are separated from gangue by froth flotation or magnetic separation processes. After this, the ore is subjected to roasting and smelting. These steps are carried out initially in rotary kilns or multihearth furnaces and then smelting is done in either blast furnaces or reverberatory, or arc furnaces. Most sulfur is removed as sulfur dioxide. Iron and other oxides produced in roasting are also removed along with siliceous slag during smelting. A matte obtained after smelting usually contains impure nickel-iron-copper sulfides and sulfur. The molten matte is treated with silica and an air blower in a converter in the Bessemerizing stage to remove all remaining iron and sulfur.
Copper-nickel matte obtained in this stage is allowed to cool slowly over a few days to separate mineral crystals of copper sulfide, nickel sulfide and nickel-copper alloy. The cool matte is pulverized to isolate sulfides of nickel and copper by froth flotation. Nickel-copper alloy is extracted by magnetic separation. Nickel metal is obtained from the nickel sulfide by electrolysis using crude nickel sulfide cast into anodes and nickel-plated stainless steel cathodes.
Alternatively, nickel sulfide is roasted to nickel oxide, which then is reduced to crude nickel and is electrorefined as above.
Two other refining processes are also frequently employed. One involves hydrometallurgical refining in which sulfide concentrates are leached with ammonia solution to convert the copper, nickel, and cobalt sulfides into their complex amines. Copper is precipitated from this solution upon heating. Under such conditions, the sulfide-amine mixture of nickel and cobalt are oxidized to their sulfates. The sulfates then are reduced to metallic nickel and cobalt by heating with hydrogen at elevated temperatures under pressure. The metals are obtained in their powder form.
The more common carbonyl refining process involves reaction of crude nickel with carbon monoxide under pressure at 100°C to form nickel tetracarbonyl, Ni(CO)4. The liquid tetracarbonyl upon heating at 300°C decomposes to nickel metal and carbon monoxide. Very pure nickel can be obtained by the carbonyl refining processes, as no other metal forms a similar carbonyl under these conditions.


At ordinary temperatures, bulk nickel in compact form has no perceptible reactivity with air or water. However, in finely-divided state, the metal reacts readily and can be pyrophoric under certain conditions. When heated in air at 400°C or with steam, nickel converts to its oxide, NiO.
When heated with bromine vapors or chlorine gas, nickel catches fire forming nickel bromide, NiBr2, and yellow nickel chloride, NiCl2, respectively. Finely divided nickel combines with carbon monoxide to form zero valent nickel tetracarbonyl, Ni(CO)4. The reaction occurs at 50°C and one atmosphere, although it is usually carried out at 200°C under high CO pressure between 100 to 400 atm for high yield of carbonyl, and to prevent product decomposition. Carbon monoxide at ordinary pressure may be passed over freshly reduced metal to form the tetracarbonyl.
Finely divided nickel absorbs a large volume of hydrogen at high temperatures. Even at ordinary temperatures, considerable occlusion of hydrogen occurs on to the metal surface and no definite composition of any hydride formed is known. The metal activates molecular hydrogen to its atomic state, contributing to its catalytic action in hydrogenation of unsaturated compounds.
Dilute mineral acids attack nickel to a varying extent. The metal dissolves readily in dilute nitric acid. Evaporation of the solution forms emerald green crystals of nickel nitrate hexahydrate, Ni(NO3)2•6H2O.
Actions of dilute hydrochloric and sulfuric acid on nickel are relatively slow: slower than on iron. Concentrated nitric acid passivates the metal, oxidizing it and forming a protective film on its surface which prevents any further reaction.
Nickel is stable in caustic alkalies. At moderate temperatures, it decomposes gaseous ammonia into hydrogen and nitrogen. Nickel combines with sulfur, phosphorus, carbon, arsenic, antimony, and aluminum at elevated temperatures. Fusion of nickel powder with molten sulfur yields nickel sulfide, NiS. Reaction with aluminum can be explosive at 1,300°C, forming nickelaluminum intermetallic products of varying compositions.
Nickel powder combines with carbon dioxide in ammonia solution forming nickel carbonate. Boiling the solution to expel ammonia precipitates pure carbonate, NiCO3.
Fine nickel powder reacts with sulfamic acid in hot aqueous solution under controlled conditions, forming nickel sulfamate tetrahydrate, Ni(SO3NH2)2•4H2O, used in electroplating baths.


Skin contact can cause dermatitis and a type of chronic eczema, known as “nickel itch”, caused by hypersensitivity reactions of nickel on the skin (Patnaik, P. 1999. A Comprehensive Guide to the Hazardous Properties of Chemical Substances, 2nd ed. pp. 621-622, New York: John Wiley & Sons.) Although oral toxicity of the metal is very low, ingestion may cause hyperglycemia and depression of the central nervous system. Chronic inhalation of nickel dust can cause lung and sinus cancers in humans. Nickel and certain of its compounds are listed by IARC under Group 2B carcinogens as “possibly carcinogenic to humans” (International Agency for Research on Cancer. 1990. IARC Monograph, Vol. 49: Geneva.)


Nickel is a hard, silvery white, malleable metal chunk or grey powder. Nickel powder is pyrophoric – can ignite spontaneously. It may react violently with titanium, ammonium nitrate, potassium perchlorate, and hydrazoic acid. It is incompatible with acids, oxidising agents, and sulphur. The industrially important nickel compounds are nickel oxide (NiO), nickel acetate (Ni(C2H3O2), nickel carbonate (NiCO3), nickel carbonyl (Ni(CO)4), nickel subsulphide (NiS2), nickelocene (C5H5)2Ni, and nickel sulphate hexahydrate (NiSO4 · 6H2O). Nickel compounds have been well established as human carcinogens. Investigations into the molecular mechanisms of nickel carcinogenesis have revealed that not all nickel compounds are equally carcinogenic: certain water-insoluble nickel compounds exhibit potent carcinogenic activity, whereas highly water-soluble nickel compounds exhibit less potency. The reason for the high carcinogenic activity of certain water-insoluble nickel compounds relates to their bioavailability and the ability of the nickel ions to enter cells and reach chromatin. The water-insoluble nickel compounds enter cells quite efficiently via phagocytic processes and subsequent intracellular dissolution. Nickel is classified as a borderline metal ion because it has both soft and hard metal properties and it can bind to sulphur, nitrogen, and oxygen groups. Nickel ions are very similar in structure and coordination properties to magnesium.

Chemical Properties

silver white, hard, malleable metal chunks or grey powder

Chemical Properties

RANEY NICKEL is a hard, ductile, magnetic metal with a silver-white color.

Physical properties

Nickel metal does not exist freely in nature. Rather, it is located as compounds in ores ofvarying colors, ranging from reddish-brown rocks to greenish and yellowish deposits, andin copper ores. Once refined from its ore, the metallic nickel is a silver-white and hard butmalleable and ductile metal that can be worked hot or cold to fabricate many items. Nickel,located in group 10, and its close neighbor, copper, just to its right in group 11 of the periodictable, have two major differences. Nickel is a poor conductor of electricity, and copper is anexcellent conductor, and although copper is not magnetic, nickel is. Nickel’s melting point is1,455°C, its boiling point is 2,913°C, and its density is 8.912 g/cm3.


There are 31 isotopes of nickel, ranging from Ni-48 to Ni-78. Five of these arestable, and the percentage of their contribution to the element’s natural existence onEarth are as follows: Ni-58 = 68.077%, Ni-60 = 26.223%, Ni-61 = 1.140%, Ni-62 =3.634%, and Ni 64 = 0.926%. All of the other 26 isotopes of nickel are artificially madeand radioactive with half-lives ranging from a few nanoseconds to 7.6×104 years.

Origin of Name

The name is derived from the ore niccolite, meaning “Old Nick,” referred to as the devil by German miners. The niccolite mineral ore was also called “kupfernickel,” which in German stands for two things; first, it is the name of a gnome (similar to Cobalt), and second, it refers to “Old Nick’s false copper.”


Nickel is the 23rd most abundant element found in the Earth’s crust. It is somewhat plentiful but scattered and makes up one-hundredth of 1% of igneous rocks. Nickel metal is foundin meteorites (as are some other elements). It is believed that molten nickel, along with iron,makes up the central sphere that forms the core of the Earth.There are several types of nickel ores. One is the major ore for nickel called pentlandite(NiS ? 2FeS), which is iron/nickel sulfide. Another is a mineral called niccolite (NiAs), discovered in 1751 and first found in a mining area of Sweden. By far, the largest mining area fornickel is located in Ontario, Canada, where it is recovered from what is thought to be a verylarge meteorite that crashed into the Earth eons ago. This large nickel deposit is one reasonfor the theory of the Earth’s core being molten nickel and iron, given that both the Earth andmeteorites were formed during the early stages of the solar system. Some nickel ores are alsofound in Cuba, the Dominican Republic, and Scandinavia. Traces of nickel exist in soils, coal,plants, and animals.


As mentioned, nickel is located in group 10 (VIII) and is the third element in the specialtriad (Fe, Co, Ni) of the first series of the transition elements. Nickel’s chemical and physicalproperties, particularly its magnetic peculiarity, are similar to iron and cobalt.Some acids will attack nickel, but it offers excellent protection from corrosion from air andseawater. This quality makes it excellent for electroplating other metals to form a protectivecoating. Nickel is also an excellent alloy metal, particularly with iron, for making stainless steelas well as a protective armor for military vehicles. It is malleable and can be drawn throughdies to form wires. About one pound of nickel metal can be drawn to about 200 miles of thinwire.


Discovered by Cronstedt in 1751 in kupfernickel (niccolite). Nickel is found as a constituent in most meteorites and often serves as one of the criteria for distinguishing a meteorite from other minerals. Iron meteorites, or siderites, may contain iron alloyed with from 5 to nearly 20% nickel. Nickel is obtained commercially from pentlandite and pyrrhotite of the Sudbury region of Ontario, a district that produces much of the world’s nickel. It is now thought that the Sudbury deposit is the result of an ancient meteorite impact. Large deposits of nickel, cobalt, and copper have recently been developed at Voisey’s Bay, Labrador. Other deposits of nickel are found in Russia, New Caledonia, Australia, Cuba, Indonesia, and elsewhere. Nickel is silvery white and takes on a high polish. It is hard, malleable, ductile, somewhat ferromagnetic, and a fair conductor of heat and electricity. It belongs to the iron-cobalt group of metals and is chiefly valuable for the alloys it forms. It is extensively used for making stainless steel and other corrosion- resistant alloys such as Invar?, Monel?, Inconel?, and the Hastelloys?. Tubing made of a copper-nickel alloy is extensively used in making desalination plants for converting sea water into fresh water. Nickel is also now used extensively in coinage and in making nickel steel for armor plate and burglar-proof vaults, and is a component in Nichrome?, Permalloy?, and constantan. Nickel added to glass gives a green color. Nickel plating is often used to provide a protective coating for other metals, and finely divided nickel is a catalyst for hydrogenating vegetable oils. It is also used in ceramics, in the manufacture of Alnico magnets, and in batteries. The sulfate and the oxides are important compounds. Natural nickel is a mixture of five stable isotopes; twenty-five other unstable isotopes are known. Nickel sulfide fume and dust, as well as other nickel compounds, are carcinogens. Nickel metal (99.9%) is priced at about $2/g or less in larger quantities.


Nickel-plating; for various alloys such as new silver, Chinese silver, German silver; for coins, electrotypes, storage batteries; magnets, lightning-rod tips, electrical contacts and electrodes, spark plugs, machinery parts; catalyst for hydrogenation of oils and other organic substances. See also Raney nickel. manufacture of Monel metal, stainless steels, heat resistant steels, heat and corrosion resistant alloys, nickel-chrome resistance wire; in alloys for electronic and space applications.


The most common use of nickel is as an alloy metal with iron and steel to make stainlesssteel, which contains from 5% to 15% nickel. The higher the percentage of nickel in stainlesssteel, the greater the steel’s resistance to corrosion—particularly when exposed to seawater.Nickel is also alloyed with copper to make Monel metal, which was widely used before stainless steel became more economical and practical. It was used for many purposes as varied ashousehold appliances and general manufacturing. Nickel is also used to electroplate othermetals to provide a noncorrosive protective and attractive finish.The 5-cent coin of the United States is named after the metal nickel. It is composed of25% nickel and 75% copper (maybe it should have been named “copper,” but that name wasalready used in England for a coin). Thousands of years ago, a variety of metals, mainly goldand silver, were used to make coins. Because of the shortage and price increase of some coinagemetals such as gold, silver, and copper, the United States mint now uses less of these metalsand substitutes more iron, zinc, nickel, or steel to make the coins of today.As mentioned, nickel is one of the three unique magnetic metals (Fe, Co, Ni) and is alloyedwith iron, cobalt, and aluminum to make powerful Alnico magnets.When nickel is alloyed with chromium, it forms what is known as Ni-Chrome, which hasa rather high resistance to electrical currents, meaning that electron flow is impeded in theconductor to the point that it results in the rapid vibration of the atoms and molecules of themetal conductor, thus producing heat. This property, along with the element’s high meltingpoint and the fact that it can be drawn into different size wires, makes nickel ideal in themanufacture of heating elements in toasters and other appliances that convert electrical energyinto heat. Because of their superior heat conductivity and resistance to corrosion, nickel alloysare excellent metals for manufacturing cookware.A more recent use of nickel is in the manufacture of the rechargeable nickel-chrome electric cell. One of the electrodes in this type of cell (battery) is nickel (II) oxide (Ni2+ + O2-→ NiO). (Note: When two or more cells are combined in an electrical circuit, they form abattery, but when just one is referred to, it is called a cell.) Although the electrical output ofa Ni-Chrome cell is only 1.4 volts (as compared to 1.5 volts dry cells), Ni-Chrome has manyuses in handheld instruments such as calculators, computers, electronic toys, and other portable electronic devices.Powdered nickel metal acts as a catalyst for the hydrogenation of vegetable oils. (See theentry for hydrogen for more on hydrogenation.


Nickel is used in various alloys, such asGerman silver, Monel, and nickel–chrome;for coins; in storage batteries; in spark plugs;and as a hydrogenation catalyst.


ChEBI: Chemical element (nickel group element atom) with atomic number 28.


A transition metal that occurs naturally as the sulfide and silicate. It is extracted by the Mond process, which involves reduction of nickel oxide using carbon monoxide followed by the formation and subsequent decomposition of volatile nickel carbonyl. Nickel is used as a catalyst in the hydrogenation of alkenes, e.g. margarine manufacture, and in coinage alloys. Its main oxidation state is +2 and these compounds are usually green. Symbol: Ni; m.p. 1453°C; b.p. 2732°C; r.d. 8.902 (25°C); p.n. 28; r.a.m. 58.6934.


nickel: Symbol Ni. A malleable ductilesilvery metallic transition element;a.n. 28; r.a.m. 58.70; r.d. 8.9;m.p. 1450°C; b.p. 2732°C. It is foundin the minerals pentlandite (NiS),pyrrhoite ((Fe,Ni)S), and garnierite((Ni,Mg)6(OH)6Si4O11.H2O). Nickel isalso present in certain iron meteorites(up to 20%). The metal isextracted by roasting the ore to givethe oxide, followed by reductionwith carbon monoxide and purificationby the Mond process. Alternativelyelectolysis is used. Nickel metalis used in special steels, in Invar, and,being ferromagnetic, in magnetic alloys,such as Mumetal. It is also aneffective catalyst, particularly for hydrogenation reactions (see also raneynickel). The main compounds areformed with nickel in the +2 oxidationstate; the +3 state also exists (e.g.the black oxide, Ni2O3). Nickel wasdiscovered by Axel Cronstedt(1722–65) in 1751.

General Description

Nickel catalyst, is extremely fine powdered nickel. Nickel is grayish colored. Insoluble in water. Nickel catalyst is used to promote the chemical action in manufacturing synthetics and to process vegetable oil and petroleum. If exposed to air or moisture, Nickel may become hot enough to ignite. Nickel is insoluble in water and does not react with larger volumes of water.

Air & Water Reactions

Pyrophoric, Ignites spontaneously in the presence of air; during storage, H2 escapes with fire and explosion hazards; reacts violently with acids forming H2. [Handling Chemicals Safely 1980. p. 807].

Reactivity Profile

Metals, such as METAL CATALYST, are reducing agents and tend to react with oxidizing agents. Their reactivity is strongly influenced by their state of subdivision: in bulk they often resist chemical combination; in powdered form they may react very rapidly. Thus, as a bulk metal Nickel is somewhat unreactive, but finely divided material may be pyrophoric. The metal reacts exothermically with compounds having active hydrogen atoms (such as acids and water) to form flammable hydrogen gas and caustic products. The reactions are less vigorous than the similar reactions of alkali metals, but the released heat can still ignite the released hydrogen. Materials in this group may react with azo/diazo compounds to form explosive products. These metals and the products of their corrosion by air and water can catalyze polymerization reactions in several classes of organic compounds; these polymerizations sometimes proceed rapidly or even explosively. Some metals in this group form explosive products with halogenated hydrocarbons. Can react explosively with oxidizing materials.


Flammable and toxic as dust or fume. Dermatitis and pneumoconiosis. A confirmed carcinogen


Nickel dust and powder are flammable. Most nickel compounds, particularly the salts, aretoxic. NiSO4 is a known carcinogen.
Although nickel is not easily absorbed in the digestive system, it can cause toxic reactionsand is a confirmed carcinogen in high concentration in the body. Nickel workers can receivesevere skin rashes and lung cancer from exposure to nickel dust and vapors.
Nickel is stored in the brain, spinal cord, lungs, and heart. It can cause coughs, shortnessof breath, dizziness, nausea, vomiting, and general weakness.

Health Hazard

Fire will produce irritating, corrosive and/or toxic gases. Inhalation of decomposition products may cause severe injury or death. Contact with substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution.

Health Hazard

Ingestion of nickel can cause hyperglycemia,depression of the central nervous system,myocardial weakness, and kidney damage.A subcutaneous lethal dose in rabbits isin the range 10 mg/kg. The oral toxicityof the metal, however, is very low. Skincontact can lead to dermatitis and “nickelitch,” a chronic eczema, caused by dermalhypersensitivity reactions. Nickel itch mayresult from wearing pierced earrings. Inhalationof metal dusts can produce irritation ofthe nose and respiratory tract. Nickel andsome of its compounds have been reportedto cause lung cancer in experimental animals.It may also induce cancer in nose,stomach, and possibly the kidney. The experimentaldata on the latter, are not fully confirmative.Nickel refinery flue dust, nickelsulfide (Ni3S2) , and nickeloxide (NiO) produced localizedtumors in experimental animals wheninjected intramuscularly. IARC has classifiednickel and its compounds as carcinogenicto humans (IARC 1990). Inhalation ofmetal dusts can produce lung and sinus cancersin humans, with a latent period of about25 years.
Nickel is susceptible to cross human placentaand produce teratogenesis and embroytoxicity. In vitro study on lipid peroxidationindicated that nickel induced peroxidativedamage to placental membrane causing decreased placental viability, altered permeabilityand subsequent embroy toxicity (Chenand Lin 1998). In a latter study, Chen et al.(2003) evaluated nickel-induced oxidativestress and effects of antioxidants in humanlymphocytes. The levels of intracellular reactiveoxygen species, lipid peroxidation andhydroxyl radicals were examined for one hourfollowing acute treatment with Nicl2. Thestudy showed that glutathione, catalase andmannitol each provided protection against theoxidative stress induced by Ni.
The efficacy of organic chelating ligandsin cleaning human skin contaminated withnickel has been investigated (Healy et al.1998). Commercial liquid soap added withL-histidine was found to be more effectivethan the untreated soap. Similarly sodiumethylenediamine tetraacetic acid (EDTA)salt or L-histidine added to phosphate buffersaline solution was more effective in cleaningnickel contaminated human skin than thephosphate saline alone.

Fire Hazard

Flammable/combustible material. May ignite on contact with moist air or moisture. May burn rapidly with flare-burning effect. Some react vigorously or explosively on contact with water. Some may decompose explosively when heated or involved in a fire. May re-ignite after fire is extinguished. Runoff may create fire or explosion hazard. Containers may explode when heated.

Agricultural Uses

Nickel (Ni) is a silver-white, ductile, malleable, yet tough metallic element of Group 10 (formerly Group VIII) of the Periodic Table. Mostly, nickel goes into the making of steel and other corrosion resistant alloys. Finely divided nickel is used as a hydrogenation catalyst. Nickel is a beneficial trace element for plants.
Its presence in the urease enzyme underlines its importance as a functional element. It is essential for grain viability, in barley and at concentrations less than 100 μg/kg, the grain level and the germination frequency decrease progressively. The quantity of Ni in a few fertilizers is as given: 2 ppm in nitrochalk, 13 ppm in superphosphate and 10 ppm in FYM.
Nickel is the metal component of urease that hydrolyzes urea to give ammonia and carbon dioxide. Compounds that react with nickel in the urease molecule inhibit the hydrolysis of urea.
Nickel enhances the nodule weight and the seed yield of soybeans, chickpeas and temperate cereals. It is present in plants in the range of 0.1 to 1O ppm of the dry weight.
High levels of Ni may induce Zn or Fe deficiency because of cation competition, and may create nickel toxicity. The browning and necrosis of the leaf tips and margins are the toxicity symptoms on the plant. High Ni content also causes the distortion of young leaves and the death of the terminal shoots of the plant. The emerging leaves may fail to unroll and become necrotic, with the necrosis starting from near the base and spreading toward the leaf tip. Nickel toxicity in cereals and grasses varies in the intensity of chlorosis along the length of the leaf with a series of transverse bands.
Sewage sludge contains heavy metals like Ni, Cd, etc. that are absorbed by plants grown in soils contaminated with these heavy metals. The toxicity caused by these metals is in turn, passed on to animals that feed on such plants. Any regulation for sludge use should ensure that the soil pH is not lower than 6.5, as heavy metals are insoluble at pH greater than 6.5.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion, intratracheal, intraperitoneal, subcutaneous, and intravenous routes. An experimental teratogen. Ingestion of soluble salts causes nausea, vomiting, and diarrhea. Mutation data reported. Hypersensitivity to nickel is common and can cause allergic contact dermatitis, pulmonary asthma, conjunctivitis, and inflammatory reactions around nickel-containing medcal implants and prostheses. Powders may ignite spontaneously in air. Reacts violently with F2, NH4NO3, hydrazine, NH3, (H2 + dioxane), performic acid, P, Se, S, (Ti + KCLO3). Incompatible with oxidants (e.g., bromine pentafluoride, peroxyformic acid, potassium perchlorate, chlorine, nitryl fluoride, ammonium nitrate), Raney-nickel catalysts may initiate hazardous reactions with ethylene + aluminum chloride, pdioxane, hydrogen, hydrogen + oxygen, magnesium silicate, methanol, organic solvents + heat, sulfur compounds. Nickel catalysts have caused many industrial accidents.

Potential Exposure

Nickel is used as an alloy additive in steel manufacture; in the production of coins and other utensils. Nickel forms alloys with copper, manganese, zinc, chromium, iron, molybdenum, etc. Stainless steel is the most widely used nickel alloy. An important nickel copper alloy is Monel metal, which contains 66% nickel and 32% copper and has excellent corrosion resistance properties. Permanent magnets are alloys chiefly of nickel, cobalt, aluminum, and iron. Elemental nickel is used in electroplating, anodizing aluminum casting operations for machine parts; and in coinage; in the manufacture of acid-resisting and magnetic alloys; magnetic tapes; surgical and dental instruments; nickel cadmium batteries; nickel soaps in crankcase oil; in ground-coat enamels; colored ceramics; and glass. It is used as a catalyst in the hydrogenation synthesis of acrylic esters for plastics. Exposure to nickel may also occur during mining, smelting, and refining operations. The route by which most people in the general population receive the largest portion of daily nickel intake is through food. Based on the available data from composite diet analysis, between 300 and 600 μg nickel per day are ingested. Fecal nickel analysis, a more accurate measure of dietary nickel intake, suggests about 300 μg per day. The highest level of nickel observed in water was 75 μg/L. Average drinking water levels are about 5 μg/L. A typical consumption of 2 L daily would yield an additional 10 μg of nickel, of which up to 1 μg would be absorbed.


Metallic nickel is reasonably anticipated to be a human carcinogenbased on sufficient evidence of carcinogenicity from studies in experimental animals.


UN3089 Metal powders, flammable, n.o.s., Hazard Class: 4.1; Labels: 4.1-Flammable solid. UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard Class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.


Nickel dust is a spontaneously flammable solid and a dangerous fire hazard.

Waste Disposal

Nickel compoundsencapsulation followed by disposal in a chemical waste landfill. However, nickel from various industrial wastes may also be recovered and recycled as described in the literature.

Nickel Preparation Products And Raw materials

Raw materials

Preparation Products

Nickel Suppliers

Global( 245)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
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Mainchem Co., Ltd.
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Haihang Industry Co.,Ltd
+86 531 8582 1093 CHINA 8921 58
Hubei xin bonus chemical co. LTD
027-59338440 CHINA 23049 58
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123
86-21-63290778 86-21-63218885 China 9847 79
Rush Metal 021-60516075
021-60516075 CHINA 21 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
86-10-82849933; China 96815 76

View Lastest Price from Nickel manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-08-30 Nickel
US $1.00 / KG 1KG 85.0-99.8% 200kg career henan chemical co

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